The Analgesic Effect of Pericapsular Nerve Group Block With Lateral Femoral Cutaneous Nerve Block and Pericapsular Nerve Group Block With Supra-inguinal Fascia Iliaca Block in Hip Hemiarthroplasty

NCT06577103 | Completed

• 1 other identifier: FMASU MD345/2023
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to investigate the efficiency of preoperative and post-operative analgesia by pericapsular nerve group block (PENG) block with supra-inguinal fascia iliaca block (SIFIC) block compared with PENG block with lateral femoral cutaneous nerve block (LFCN) block in ease of giving a sitting position for spinal anesthesia and reducing narcotic consumption during the first 24 hour post-operatively and functional recovary by using the Visual analogue scale (VAS) of pain.

Conditions

Pericapsular Nerve Group Block; Lateral Femoral Cutaneous Nerve Block; Supra-inguinal Fascia Iliaca Block; Hip Hemiarthroplasty

Outcome Measures

Primary Outcomes (1)

• Degree of pain

  Degree of pain will be assessed by visual analogue score (VAS). VAS ranging from 0 to 10, where 0 is no pain and 10 is maximum pain. It will be assessed preoperatively first after the block application then postoperatively, at post anesthesia care unit (PACU) and then 2, 6 ,12 ,18 ,24 hours postoperatively.

  24 hours postoperatively

Secondary Outcomes (4)

• The ease of giving a sitting position for spinal anesthesia (EOSP)

  Intraoperatively

• The total dose of nalbuphine consumption

  24 hours postoperatively

• The number of patients who needed rescue analgesia

  24 hours postoperatively

• Ablility to walk with support within 24 hours

  24 hours postoperatively

Study Arms (2)

Pericapsular nerve group block (PENG) with supra-inguinal fascia iliaca block (SIFIC)

EXPERIMENTAL

Patients will receive pericapsular nerve group (PENG) block with supra-inguinal fascia iliaca (SIFIC) block.

Other: Pericapsular nerve group block (PENG) with supra-inguinal fascia iliaca block (SIFIC)

Pericapsular nerve group block (PENG) with lateral femoral cutaneous nerve block (LFCN)

EXPERIMENTAL

Patients will receive pericapsular nerve group (PENG) block with lateral femoral cutaneous nerve (LFCN) block.

Other: Pericapsular nerve group block (PENG) with lateral femoral cutaneous nerve block (LFCN)

Interventions

Pericapsular nerve group block (PENG) with supra-inguinal fascia iliaca block (SIFIC) OTHER

Patients will receive pericapsular nerve group (PENG) block with supra-inguinal fascia iliaca (SIFIC) block.

Pericapsular nerve group block (PENG) with supra-inguinal fascia iliaca block (SIFIC)

Pericapsular nerve group block (PENG) with lateral femoral cutaneous nerve block (LFCN) OTHER

Patients will receive pericapsular nerve group (PENG) block with lateral femoral cutaneous nerve (LFCN) block.

Pericapsular nerve group block (PENG) with lateral femoral cutaneous nerve block (LFCN)

Eligibility Criteria

• Age: 40 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 40-80 years.
• Sex: Both sexes.
• American Society of Anaesthesiologists (ASA) Physical Status Class I, II, and III.
• Scheduled for hip hemiarthroplasty under general anesthesia.

You may not qualify if:

• Declining to give a written informed consent.
• History of allergy to the medications used in the study.
• Contraindications to regional anesthesia (including patient refusal, coagulopathy and local infection).
• Psychiatric disorders or narcotic abusers.
• Significant cognitive dysfunction.
• American Society of Anesthesiologists (ASA) Physical Status Class IV.
• Renal insufficiency (to avoid local anesthetic or nalbuphine metabolites adverse effect)
• Opioid abuser patients
• Pregnancy.

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Ain Shams University

Cairo, Cairo Governorate, 11591, Egypt

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Ain Shams University,Egypt

Study Record Dates

• First Submitted: August 27, 2024
• First Posted: August 29, 2024
• Study Start: January 2, 2024
• Primary Completion: October 1, 2024
• Study Completion: December 1, 2024
• Last Updated: May 2, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)