NCT06230575

Brief Summary

Breast surgeries are common operative procedures that require appropriate postoperative analgesia.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
188

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Feb 2024

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 21, 2024

Completed
9 days until next milestone

First Posted

Study publicly available on registry

January 30, 2024

Completed
2 days until next milestone

Study Start

First participant enrolled

February 1, 2024

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 15, 2025

Completed
23 days until next milestone

Study Completion

Last participant's last visit for all outcomes

November 7, 2025

Completed
Last Updated

November 19, 2025

Status Verified

November 1, 2025

Enrollment Period

1.7 years

First QC Date

January 21, 2024

Last Update Submit

November 16, 2025

Conditions

Analgesia

Outcome Measures

Primary Outcomes (1)

  • time to receive first postoperative analgesic

    time to first dose of rescue opioid analgesic

    First 24 hours postoperatively

Study Arms (4)

erector spinae block

ACTIVE COMPARATOR

Erector spinae plane block on the ipsilateral operative site

Procedure: erector spinae block

retrolaminar block

EXPERIMENTAL

Retrolaminar plane block on the ipsilateral operative site

Procedure: retrolaminar block

serratus anterior block

EXPERIMENTAL

Serratus anterior plane block on the ipsilateral operative site

Procedure: serratus anterior block

pectoral nerve block II

EXPERIMENTAL

Pectoral nerve block II on the ipsilateral operative site

Procedure: pectoral nerve block

Interventions

erector spinae blockPROCEDURE

Erector spinae plane block

erector spinae block
retrolaminar blockPROCEDURE

Retrolaminar block

retrolaminar block
serratus anterior blockPROCEDURE

Serratus anterior plane block

serratus anterior block
pectoral nerve blockPROCEDURE

Pectoral nerve block

pectoral nerve block II

Eligibility Criteria

Age18 Years - 65 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility DetailsFemale patients with breast cancer
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • female cancer breast patient
  • age from 18- 65

You may not qualify if:

  • coagulation defect
  • Patient refusal
  • abnormal kidney and or liver function tests

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Walaa Y Elsabeeny

Cairo, 11796, Egypt

Location

MeSH Terms

Conditions

Agnosia

Condition Hierarchy (Ancestors)

Perceptual DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Walaa Y Elsabeeny, MD

    Assistant professor of Anesthesia, Surgical critical care and Pain Management, National Cancer Institute, Cairo University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant professor of Anesthesia, Surgical Critical care and Pain management

Study Record Dates

First Submitted

January 21, 2024

First Posted

January 30, 2024

Study Start

February 1, 2024

Primary Completion

October 15, 2025

Study Completion

November 7, 2025

Last Updated

November 19, 2025

Record last verified: 2025-11

Locations

EG(1)