The Implementation of the Go Wish Game to Promote Advance Care Planning in Onco- Hematologic Disease

NCT06795815 | Recruiting

• 1 other identifier: OHGW-ACP
• Study Type: interventional
• Target: 75
• Locations: 1 country
• Sites: 1

Brief Summary

This is a mixed-method, device-free and drug-free multicenter interventional study. The study aims at facilitating end-of-life conversations within the doctor-patient relationship through the use of the Go Wish Game (GWG) and supporting patients, their caregivers and healthcare professionals to complete Advance Care Panning documentation. The GWG helps people clarify and identify their priorities, should they be affected by a chronic, disabling and potentially non-healing illness. In fact, the GWG consists of a small deck of cards, and on each card is a concrete action or situation that may be important to a person at the end of life. The "Onco-hema Go wish-ACP" project aims to evaluate the feasibility of a Go Wish Game-based intervention with patients with refractory lymphoma, leukemia or multiple myeloma or advanced solid tumors with prognosis \> 3 months. In terms of secondary objectives, the study aims to.

• Evaluate and compare the intervention with hematology and oncology patients in terms of: - Other feasibility indicators; Involvement in CCP pathways; Quality of communication; Meaning of life; Impact on hope; through a series of questionnaires administered to patients and caregivers involved in the intervention
• Qualitatively assess the acceptability of the intervention in terms of recruitment and delivery with patients and caregivers through semi-structured interviews and with professionals through Focus Groups (FGs).
• To analyze the clinical records of enrolled patients in terms of: values and preferences; awareness of prognosis; end-of-life choices and shared decision-making on treatment decisions.

Conditions

Leukemia; Multiple Mieloma; Advanced Solid Tumors; Lymphoma; Oncology; Hematologic Diseases

Keywords

Advance Care Planning; Go Wish Game; Medical Oncology; Hematology; Oncology; Palliative Care; Experimental Design Study; Mixed Methods

Outcome Measures

Primary Outcomes (1)

• Intervention Feasibility

  We will evaluate the feasibility of the intervention. Feasibility will be investigated by: 1. proportion of patients who will accept to participate among those screened/eligible who received the proposal to participate; 2. proportion of enrolled patients who will withdraw from the study after the first GWG discussion among the enrolled patients; 3, percentage proportion of enrolled patients who will attend all the planned GWG discussions; 4\. proportion of enrolled patients that will complete the ACP document (after participating in all the planned GWG discussions)

  1 Year

Secondary Outcomes (6)

• ACP Engagement;

  18 Months

• Quality of Communication;

  18 Months

• Meaning of Life;

  18 Months

• Impact on patients' hope

  18 Months

• Acceptability

  18 Months

Study Arms (1)

Patients affected by refractory lymphomas, or leukemia or myeloma multiple or advanced solid tumors

EXPERIMENTAL

Other: Go Wish Game

Interventions

Go Wish Game OTHER

The Go Wish Game (GWG) provides a simple tool, composed by 35 cards to identify individual priorities. GWG is welcomed as a first step in clarifying values and personal thoughts linked to the end of life. The GWG discussion will be divided into two meetings. During the first one, the physician instructs the patients and their caregivers on how the GWG works. The patient will be invited to divide the cards into three sets, labeling the content of the cards within each set as: Very important;more or less important and not important. This will be the base for the second meeting. During the second meeting - scheduled within one week - each category of card sets will be discussed with patients and their caregivers. The identification of the most relevant wishes or priorities of each patient will be incorporated into the individual therapeutic plan and the patient will be offered the option to make a formal ACP in the following 4 weeks.

Patients affected by refractory lymphomas, or leukemia or myeloma multiple or advanced solid tumors

Eligibility Criteria

• Age: 18 Years - 99 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• ≥ 18 years age; diagnosed with refractory lymphomas, or leukemia or multiple myeloma or advanced solid tumors and estimated prognosis \> 3 months;
• able to communicate in Italian and
• to give written consent to the study.

You may not qualify if:

• Patients with severe cognitive impairment or serious psychiatric condition;
• refusal to participate to the study

Sponsors & Collaborators

• Azienda USL Reggio Emilia - IRCCS: lead

Study Sites (1)

AziendaUSL IRCCS Reggio Emilia

Reggio Emilia, Italy

RECRUITING

MeSH Terms

Conditions

Leukemia; Lymphoma; Neoplasms; Hematologic Diseases

Condition Hierarchy (Ancestors)

Neoplasms by Histologic Type; Hemic and Lymphatic Diseases; Lymphoproliferative Disorders; Lymphatic Diseases; Immunoproliferative Disorders; Immune System Diseases

Central Study Contacts

Marta Perin (Dr), PhD

CONTACT

+39 3463576133; marta.perin@ausl.re.it

Andrea Fusco, MSc

CONTACT

+39 3409136595; andrea.fusco@ausl.re.it

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 8, 2025
• First Posted: January 28, 2025
• Study Start: June 30, 2025
• Primary Completion (Estimated): July 1, 2026
• Study Completion (Estimated): July 1, 2026
• Last Updated: May 7, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, CSR, ANALYTIC CODE
• Access Criteria: The access will be able only to those people in terms of clinical staff, who are involved in the study

Locations

IT (1)