Key Insights

Highlights

Success Rate

76% trial completion

Published Results

106 trials with published results (13%)

Research Maturity

321 completed trials (40% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 72/100

Termination Rate

12.7%

102 terminated out of 804 trials

Success Rate

75.9%

-10.6% vs benchmark

Late-Stage Pipeline

0%

3 trials in Phase 3/4

Results Transparency

33%

106 of 321 completed with results

Key Signals

106 with results76% success102 terminated

Data Visualizations

Phase Distribution

800Total
Not Applicable (8)
Early P 1 (18)
P 1 (744)
P 2 (27)
P 3 (2)
P 4 (1)

Trial Status

Completed321
Recruiting188
Terminated102
Unknown81
Not Yet Recruiting56
Active Not Recruiting43

Trial Success Rate

75.9%

Benchmark: 86.5%

Based on 321 completed trials

Clinical Trials (804)

Showing 20 of 20 trials
NCT06188208Phase 1TerminatedPrimary

A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130850 in Participants With Advanced Solid and Hematologic Tumors

NCT07360314Phase 1RecruitingPrimary

Anti-Ly6E Exatecan ADC M7437 in Advanced Solid Tumors

NCT05083481Phase 1TerminatedPrimary

A Study of ASP1570 Taken by Itself, or ASP1570 Taken Together With Either Pembrolizumab, Standard Therapies, or Both, in Adults With Solid Tumors

NCT06835569Phase 1Recruiting

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

NCT07161414Phase 1RecruitingPrimary

A Study to Investigate the Pharmacokinetics and Safety of Subcutaneous Rilvegostomig in Adult Participants With Advanced Solid Tumors Previously Treated With Standard of Care Therapy

NCT07534813Not ApplicableWithdrawnPrimary

A Single-Arm Clinical Study of Autologous Tumor-Infiltrating Lymphocyte Injection (GT307) in the Treatment of Metastatic and Recurrent Advanced Solid Tumors

NCT04222413Phase 1RecruitingPrimary

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

NCT02644369Phase 2Active Not Recruiting

Study of the Effects of Pembrolizumab in Patients With Advanced Solid Tumors

NCT06004245Phase 1RecruitingPrimary

A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors

NCT06178614Phase 1Recruiting

A Study of JNJ-87890387 for Advanced Solid Tumors

NCT07127874Phase 1Recruiting

A Study of PHN-012 in Patients With Advanced Solid Tumors

NCT06242691Phase 1CompletedPrimary

Safety and Efficacy of MK-1200 in Participants With Advanced Solid Tumors (MK-1200-002)

NCT06596473Phase 1RecruitingPrimary

A Study of BG-C477 in Participants With Advanced Solid Tumors

NCT06760819Phase 2RecruitingPrimary

A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

NCT06480552Phase 1RecruitingPrimary

An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

NCT05949632Phase 1TerminatedPrimary

A Study of INCB099280 in Combination With Axitinib in Adults With Advanced Solid Tumors

NCT06040541Phase 1Recruiting

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

NCT07624214Phase 1Not Yet Recruiting

Study of LT-010391 in Participants With KRAS G12D-Mutant Solid Tumors

NCT07042100Phase 1RecruitingPrimary

A Study to Test the Safety and Tolerability of SBO-154 in Patients With Advanced Solid Tumors.

NCT07077434Phase 1RecruitingPrimary

A Study to Assess Safety, Tolerability and Drug Levels of Navlimetostat (BMS-986504) in Participants With Advanced Solid Tumors

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