Effects of Core Stabilization Exercises in Children with Acute Lymphoblastic Leukemia
Examination of the Effects of Core Stabilization Exercises on Physical Function, Functional Muscle Strength, Functional Exercise Capacity, Postural Control and Fatigue in Children with Acute Lymphoblastic Leukemia Receiving Maintenance Treatment
1 other identifier
interventional
34
1 country
1
Brief Summary
The goal of this clinical trial is to investigate the effects of core stabilization exercises applied in addition to the conventional exercise program on physical function, functional muscle strength, functional exercise capacity, postural control and fatigue in children with acute lymphoblastic leukemia receiving maintenance treatment. Participants will be divided into two groups; the first group will be given a conventional exercise program, while the second group will be given core stabilization exercises in addition to the conventional exercise program.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jan 2025
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 13, 2025
CompletedStudy Start
First participant enrolled
January 14, 2025
CompletedFirst Posted
Study publicly available on registry
January 27, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
February 1, 2026
CompletedJanuary 31, 2025
January 1, 2025
1 year
January 13, 2025
January 29, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (10)
Timed Up and Go Test (TUG)
This test aims to evaluate the physical function.
Before 8 weeks of treatment
Timed Up and Go Test (TUG)
This test aims to evaluate the physical function.
After 8 weeks of treatment
Sit-up Test
This test aims to evaluate the functional muscle strength
Before 8 weeks of treatment
Sit-up Test
This aims to evaluate the functional muscle strength.
After 8 weeks of treatment
6-Minute Walk Test
This test aims to evaluate the functional exercise capacity.
Before 8 weeks of treatment
6-Minute Walk Test
This test aims to evaluate the functional exercise capacity.
After 8 weeks of treatment
Balance Error Scoring System
This test aims to evaluate the postural control.
Before 8 weeks of treatment
Balance Error Scoring System
This test aims to evaluate the postural control.
After 8 weeks of treatment
Pediatric Quality of Life Multidimensional Fatigue Scale
This scale aims to evaluate the fatigue in pediatric patients.
Before 8 weeks of treatment
Pediatric Quality of Life Multidimensional Fatigue Scale
This scale aims to evaluate the fatigue in pediatric patients.
After 8 weeks of treatment
Study Arms (2)
Control group
EXPERIMENTALExercises will be applied to the participants participating in the study 3 days a week, 8 weeks, and 24 sessions in total.
Intervention group
EXPERIMENTALExercises will be applied to the individuals participating in the study 3 days a week, 8 weeks, and 24 sessions in total. Exercises will be applied after the conventional therapy sessions.
Interventions
Aerobic exercise and stretching exercises will be applied in the conventional exercise program. A 20-30 minute walking will be done as aerobic exercise. Stretching exercises will be done for major muscle groups in 3 sets and 10 repetitions.
In addition to the conventional exercise program, core stabilization exercises will be applied. During the exercises, participants will be trained on neutralizing the spine and working the transverse abdominis and multifidus muscles, correct postural control, and performing the exercises with diaphragmatic breathing.
Eligibility Criteria
You may qualify if:
- Children aged 7-18
- Diagnosed with ALL
- In the maintenance phase of chemotherapy
- Children without acute thrombosis, active ischemia, hemodynamic instability
- Children without uncontrolled pain
- Children who can follow verbal instructions.
You may not qualify if:
- Children who have received or are receiving cranial radiotherapy
- Children with any cardiovascular disease, acute or chronic respiratory disease
- Children with acute or chronic bone, joint, muscle problems
- Children diagnosed with neuromotor deficits or genetic disorders
- Children with vision problems other than refractive errors
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Karamanoğlu Mehmetbey Universitylead
- Saglik Bilimleri Universitesicollaborator
Study Sites (1)
Necmettin Erbakan University
Konya, 42090, Turkey (Türkiye)
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Melike Müsevitoğlu
Study Record Dates
First Submitted
January 13, 2025
First Posted
January 27, 2025
Study Start
January 14, 2025
Primary Completion
February 1, 2026
Study Completion
February 1, 2026
Last Updated
January 31, 2025
Record last verified: 2025-01
Data Sharing
- IPD Sharing
- Will not share