NCT06780072

Brief Summary

In the quest for optimal physical and mental performance and recovery, people are constantly exploring various strategies to enhance their overall well-being. Daytime napping helps mitigate the effects of inadequate nighttime sleep, allowing people to reduce fatigue and potentially improve physical performance. Research has also shown that strategically timed naps can significantly boost athletic performance, improve cognitive function, and reduce daytime fatigue. Short naps lasting between 10 to 60 minutes are ideal for quickly boosting alertness and cognitive function. Additionally, they can facilitate a complete sleep cycle, including REM sleep, which is crucial for both physical and mental recovery. Massage therapy, recognized for its ability to alleviate muscle soreness, improve circulation, and induce relaxation and it might play a crucial role in facilitating a good night sleep. In athletes a massage therapy serves as both a proactive and reactive measure in optimizing sports and exercise performance, ensuring athletes are physically and mentally prepared for competition while also facilitating their recovery, minimizing the risk of injury and being particularly effective in alleviating pain. Massage therapy significantly contributes to improving night sleep efficiency as well as the duration of sleep onset.\[12\] From a biochemical point of view, massage promotes the release of serotonin, a hormone that enhances the sense of wellbeing. In addition, serotonin is a biosynthetic precursor of melatonin and an active neurotransmitter, whose levels affect various functions of the body including sleep promotion,\[14\] while can play a significant role in mental health as it regulates mood and emotional well-being. Nowadays, massage has evolved into various types that are specialized for the treatment of various health problems. The most well know and frequently used types of massage are the "sports massage" and the "relaxation massage". Sports massage has been proven to enhance athletic performance, as well as help athletes recover after competition while the Deep Relaxation massage is used exclusively for the relaxation and psychological discharge. More specifically, the relaxation-therapeutic massage uses pressure that is deeply relaxing, but not painful, smooth gliding strokes that are both rhythmic and flowing, which increases blood circulation and promotes a general sense of relaxation. Even thought, these 2 very common types of massage have been applied for many years in various settings, it is not clear whether massage affects brain function and state of alertness. Therefore, the primary aim of the current study is to investigate the effect of two different types of manual massage sessions on daytime napping using objective (EEG - brain activity) and subjective (questionnaires) measurements of relaxation in poor sleepers.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 3, 2023

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 13, 2024

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 29, 2024

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

January 10, 2025

Completed
7 days until next milestone

First Posted

Study publicly available on registry

January 17, 2025

Completed
Last Updated

January 20, 2025

Status Verified

January 1, 2025

Enrollment Period

1.4 years

First QC Date

January 10, 2025

Last Update Submit

January 16, 2025

Conditions

Keywords

Massageday-time nappoor sleepersPSGRelaxationpower naps

Outcome Measures

Primary Outcomes (1)

  • Sleep Latency N1

    Sleep Latency N1 is the period of time between wakefulness and when sleep begins (stage 1)

    Sleep latency N1 will be calculated after the intervention (35 minutes after the initiation of the protocol)

Secondary Outcomes (1)

  • Relaxation Score

    Relaxation score is assessed at baseline and after the intervention (35 minutes after the initiation of the protocol))

Other Outcomes (1)

  • Muscle Tone

    Muscle tone will be assessed at baseline and after the intervention (35 minutes after the initiation of the protocol)

Study Arms (3)

Control

NO INTERVENTION

For the control condition (CON) participants will not receive any intervention, while they will be rested for 35 min on a massage bed

Activation Massage

EXPERIMENTAL

For the activation condition (ACT) participants will receive an activation (Sports) massage session lasting for 30 min and rest for 5 min without any interference.

Other: Activation Massage therapy

Relaxation Massage

EXPERIMENTAL

For the relaxation condition (REL) participants will receive a relaxation massage session lasting for 30 min and rest for 5 min without any interference.

Other: Relaxation Massage Therapy

Interventions

Massage Sessions Activation (Sports) massage The activation (sports) type of massage will be used as one of the massage interventions. This technique will be performed on a full body with more attention given to specific leg muscle groups such as the feet, the gastrocnemius, the femoral biceps and quadriceps and in upper body muscle groups such as the triceps, the rhomboid, the deltoid, the trapezius and head areas. Briefly, this type of massage involves a wide range of techniques that include effleurage, palmar sliding, pounding and hacking. The total duration of the activation message will be 30 minutes.

Activation Massage

Relaxation massage The Relaxation type of massage will be used as the second type of intervention in this study. This technique is designed to promote deep relaxation, reduce stress and enhance overall well-being. It is characterized by the use of four primary techniques performed on the full body, including the palms and feet. Specifically, these techniques consist of effleurage

Relaxation Massage

Eligibility Criteria

Age18 Years - 45 Years
Sexall(Gender-based eligibility)
Gender Eligibility DetailsGender at birth
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Complains of poor sleep assessed by Pittsburgh Quality Sleep Index score \>5

You may not qualify if:

  • history of mental illness,
  • dermatological diseases,
  • allergies to massage oil,
  • history of epilepsy,
  • acute or chronic condition that would limit the ability of the patient to participate in the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

School of Physical Education, Sports and Dietetics, TEFAA

Trikala, Thessaly, GR42100, Greece

Location

Related Publications (5)

  • Dakic M, Toskic L, Ilic V, Duric S, Dopsaj M, Simenko J. The Effects of Massage Therapy on Sport and Exercise Performance: A Systematic Review. Sports (Basel). 2023 May 29;11(6):110. doi: 10.3390/sports11060110.

    PMID: 37368560BACKGROUND
  • Guo J, Li L, Gong Y, Zhu R, Xu J, Zou J, Chen X. Massage Alleviates Delayed Onset Muscle Soreness after Strenuous Exercise: A Systematic Review and Meta-Analysis. Front Physiol. 2017 Sep 27;8:747. doi: 10.3389/fphys.2017.00747. eCollection 2017.

    PMID: 29021762BACKGROUND
  • Simpson NS, Gibbs EL, Matheson GO. Optimizing sleep to maximize performance: implications and recommendations for elite athletes. Scand J Med Sci Sports. 2017 Mar;27(3):266-274. doi: 10.1111/sms.12703. Epub 2016 Jul 1.

    PMID: 27367265BACKGROUND
  • Dutheil F, Danini B, Bagheri R, Fantini ML, Pereira B, Moustafa F, Trousselard M, Navel V. Effects of a Short Daytime Nap on the Cognitive Performance: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2021 Sep 28;18(19):10212. doi: 10.3390/ijerph181910212.

    PMID: 34639511BACKGROUND
  • Ntoumas I, Karatzaferi C, Boubougiatzi F, Manakou N, Aslanidi A, Giannaki CD, Papanikolaou F, Dardiotis E, Lavdas E, Sakkas GK. Massage positively influences daytime brain activity and reduces arousal state in poor sleepers: a randomized controlled trial. BMC Complement Med Ther. 2025 Jul 28;25(1):290. doi: 10.1186/s12906-025-05022-6.

MeSH Terms

Conditions

Sleep Deprivation

Condition Hierarchy (Ancestors)

DyssomniasSleep Wake DisordersNervous System DiseasesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsMental Disorders

Study Officials

  • Giorgos Sakkas, PhD

    University of Thessaly

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
CROSSOVER
Model Details: Subjects will be randomly assigned into 3 conditions each one week apart: 1) the control condition (CON) where subjects will not receive any intervention, while they were rested for 35 min on a massage bed; 2) the activation condition (ACT) where subjects will receive an activation (Sports) massage session lasting for 30 min and rested for 5 min without any interference; and 3) the relaxation condition (REL) where subjects will receive a relaxation massage session lasting for 30 min and rested for 5 min without any interference (Figure 2). All conditions will be separated by one week apart and take place at the exact time of the day, while the order of the various conditions will be randomly assigned.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

January 10, 2025

First Posted

January 17, 2025

Study Start

April 3, 2023

Primary Completion

September 13, 2024

Study Completion

November 29, 2024

Last Updated

January 20, 2025

Record last verified: 2025-01

Data Sharing

IPD Sharing
Will share

Anonymized polysomnographic data will be shared

Shared Documents
STUDY PROTOCOL, SAP, ICF
Time Frame
June 2025 - June 2030
Access Criteria
Who: Academics or Researchers after a written request What: Raw data in SPSS format How: receive a link to download the data.
More information

Locations