NCT06771986

Brief Summary

The aim of this study is to evaluate sRAGE levels in children with obesity and to determine the relationship between metabolic status and sRAGE levels in childhood obesity

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
88

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Feb 2023

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 2, 2023

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 12, 2023

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2024

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

January 3, 2025

Completed
10 days until next milestone

First Posted

Study publicly available on registry

January 13, 2025

Completed
Last Updated

January 13, 2025

Status Verified

January 1, 2025

Enrollment Period

6 months

First QC Date

January 3, 2025

Last Update Submit

January 10, 2025

Conditions

Obese Patients

Keywords

Children, obesity, sRAGE

Outcome Measures

Primary Outcomes (1)

  • Evaluation of sRAGE levels in obese and healthy participants

    From enrollment to the end of at 6 months

Interventions

ObservationOTHER

sRAGE levels were studied in three different groups

Eligibility Criteria

Age10 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodProbability Sample
Study Population

Obese and Healthy children who admitted to Kayseri City Hospital

You may qualify if:

  • Clinical diagnosis of Obesity BMI over 95th percentile BMI z-score over 2

You may not qualify if:

  • Primary hyperlipidemia Primary liver disease Hypothyroidism Diabetes

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kayseri City Hospital

Kayseri, 38080, Turkey (Türkiye)

Location

Related Publications (1)

  • Ustkoyuncu PS, Kocer D. Soluble receptor for advanced glycation end product (sRAGE) levels in adolescents with obesity, insulin resistance and metabolic syndrome: A case-control study and the review of the literature. BMC Endocr Disord. 2025 Sep 23;25(1):209. doi: 10.1186/s12902-025-02025-9.

    PMID: 40983915DERIVED

MeSH Terms

Conditions

Obesity

Interventions

Observation

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

MethodsInvestigative Techniques

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

January 3, 2025

First Posted

January 13, 2025

Study Start

February 2, 2023

Primary Completion

August 12, 2023

Study Completion

January 1, 2024

Last Updated

January 13, 2025

Record last verified: 2025-01

Data Sharing

IPD Sharing
Will not share

Locations

TU(1)