NCT06769932

Brief Summary

With the recent development of image analysis and artificial intelligence, it has become possible to measure the muscle volume from preoperative computed tomography (CT) images. Therefore, in this study, the investigators quantify the muscle volume from preoperative CT images and analyze the correlation with the dose of neuromuscular blocking agent, rocuronium, required for maintaining deep neuromuscular blockade.

Trial Health

63
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
90

participants targeted

Target at P50-P75 for all trials

Timeline
7mo left

Started Jan 2025

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress72%
Jan 2025Jan 2027

First Submitted

Initial submission to the registry

January 6, 2025

Completed
1 day until next milestone

Study Start

First participant enrolled

January 7, 2025

Completed
3 days until next milestone

First Posted

Study publicly available on registry

January 10, 2025

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 7, 2026

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

January 7, 2027

Expected
Last Updated

January 10, 2025

Status Verified

January 1, 2025

Enrollment Period

1 year

First QC Date

January 6, 2025

Last Update Submit

January 6, 2025

Conditions

Neuromuscular Blockade

Outcome Measures

Primary Outcomes (1)

  • muscle volume

    subject's muscle volume from preoperative computed tomography images.

    intraoperative period

Interventions

preoperative computed tomographyDIAGNOSTIC_TEST

subject's muscle mass from preoperative computed tomography (CT) images.

Eligibility Criteria

Age19 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients scheduled for elective colon surgery under general anesthesia

You may qualify if:

  • Those who voluntarily agreed and signed the written consent form before participating in the study
  • American Society of Anesthesiologists physical class (ASA class) 1-3
  • Patients scheduled for elective colon surgery under general anesthesia
  • Patients undergoing abdominal computed tomography for routine preoperative preparation

You may not qualify if:

  • Pregnant women
  • Decreased renal function (GFR\<60mL/min/1.73m2).
  • Patients taking drugs that affect deep neuromuscular blockade
  • Patients with a history of neuromuscular and muscle disorders

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Seoul National University Bundang Hospital

Seongnam-si, Gyunggi-do, 13620, South Korea

Location

Central Study Contacts

Insun Park, M.D./Ph.D.

CONTACT

823178777499pis121@hanmail.net

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
1 Day
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

January 6, 2025

First Posted

January 10, 2025

Study Start

January 7, 2025

Primary Completion

January 7, 2026

Study Completion (Estimated)

January 7, 2027

Last Updated

January 10, 2025

Record last verified: 2025-01

Locations

KR(1)