Skeletal Muscle Index and a Neuromuscular Blocking Agent

NCT06740877 | Not Yet Recruiting

• 1 other identifier: B-2501-947-303
• Study Type: observational
• Target: 90
• Locations: 0 countries
• Sites: N/A

Brief Summary

With the recent development of image analysis, it has become possible to measure the skeletal muscle index representing the subject's muscle mass from preoperative computed tomography (CT) images. Therefore, in this study, the investigators quantify the skeletal muscle index from preoperative CT images and analyze the correlation with the dose of neuromuscular blocking agent, rocuronium, required for maintaining deep neuromuscular blockade.

Conditions

Neuromuscular Blockade

Outcome Measures

Primary Outcomes (1)

• Skeletal Muscle index

  Muscle amount

  preoperative period

Eligibility Criteria

• Age: 19 Years - 80 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients scheduled for elective colon surgery under general anesthesia

You may qualify if:

• Those who voluntarily agreed and signed the written consent form before participating in the study
• American Society of Anesthesiologists physical class (ASA class) 1-3
• Patients scheduled for elective colon surgery under general anesthesia
• Patients undergoing abdominal computed tomography for routine preoperative preparation

You may not qualify if:

• Pregnant women
• Decreased renal function (GFR\<60mL/min/1.73m2).
• Patients taking drugs that affect deep neuromuscular blockade
• Patients with a history of neuromuscular and muscle disorders

Sponsors & Collaborators

• Seoul National University Bundang Hospital: lead

Study Officials

• Insun Park, M.D./Ph.D.

  assistant professor

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Insun Park, M.D./Ph.D.

CONTACT

823178777499; pis121@hanmail.net

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: December 13, 2024
• First Posted: December 18, 2024
• Study Start: December 25, 2024
• Primary Completion: December 25, 2025
• Study Completion (Estimated): December 25, 2026
• Last Updated: December 18, 2024

Record last verified: 2024-12