NCT06756360

Brief Summary

Neurovascular complications can result from this procedure usually from thromboembolism from the operated vessel, cerebral hypoperfusion causing ischaemia and, rarely, intracerebral haemorrhage. The overall incidence of perioperative strokes complicating CEA is approximately 4% ,and represents a devastating outcome that the procedure was designed to prevent. Other neurological sequelae complicating carotid revascularisation include cerebral hyperperfusion syndrome, cranial and peripheral nerve injuries, and contrast encephalopathy in patients undergoing CAS. The aim of this study is To evaluate the safety and efficacy of carotid endarterectomy for symptomatic carotid Stenosis patients

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
25

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jan 2025

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 17, 2024

Completed
15 days until next milestone

Study Start

First participant enrolled

January 1, 2025

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 3, 2025

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2026

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2026

Completed
Last Updated

January 3, 2025

Status Verified

January 1, 2025

Enrollment Period

1 year

First QC Date

December 17, 2024

Last Update Submit

January 1, 2025

Conditions

Carotid Stenosis

Keywords

carotid endarterectomy

Outcome Measures

Primary Outcomes (2)

  • rate of post operative ipsilateral stroke

    rate of post operative ipsilateral stroke

    30 day

  • mortality rate

    short term mortality rate postoperative

    30 day

Study Arms (1)

carotid artery stenosis patient

patients will subjected to Preoperative Carotid doppler - CT angiography Postoperative carotid doppler-CT angiography after 3 days

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Symptomatic carotid artery stenosis with Carotid artery stenosis more than 60 %

You may qualify if:

  • Symptomatic carotid artery stenosis
  • Carotid artery stenosis more than 60 %

You may not qualify if:

  • Patient with other etiology (vasculitis dissection)
  • Patient with mild Stenosis
  • Asymptomatic

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Saxena A, Ng EYK, Lim ST. Imaging modalities to diagnose carotid artery stenosis: progress and prospect. Biomed Eng Online. 2019 May 28;18(1):66. doi: 10.1186/s12938-019-0685-7.

    PMID: 31138235RESULT

MeSH Terms

Conditions

Carotid Stenosis

Condition Hierarchy (Ancestors)

Carotid Artery DiseasesCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesArterial Occlusive DiseasesVascular DiseasesCardiovascular Diseases

Central Study Contacts

Helal sayed Ali, resident doctor

CONTACT

01128674297symd2030@gmail.com

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
resident doctor at Assiut University hospital

Study Record Dates

First Submitted

December 17, 2024

First Posted

January 3, 2025

Study Start

January 1, 2025

Primary Completion

January 1, 2026

Study Completion

March 1, 2026

Last Updated

January 3, 2025

Record last verified: 2025-01