NCT06754150

Brief Summary

The goal of this multi-center observational study is to collect long-term clinical outcome information for anatomic and reverse total shoulder arthroplasty (shoulder replacement).

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,500

participants targeted

Target at P75+ for all trials

Timeline
165mo left

Started Oct 2024

Longer than P75 for all trials

Geographic Reach
1 country

6 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress10%
Oct 2024Dec 2039

Study Start

First participant enrolled

October 23, 2024

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

December 13, 2024

Completed
18 days until next milestone

First Posted

Study publicly available on registry

December 31, 2024

Completed
14.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2039

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2039

Last Updated

January 22, 2026

Status Verified

January 1, 2026

Enrollment Period

15.1 years

First QC Date

December 13, 2024

Last Update Submit

January 21, 2026

Conditions

Keywords

Shoulder ArthroplastyShoulder ReplacementAnatomic Shoulder ArthroplastyReverse Shoulder Arthroplasty

Outcome Measures

Primary Outcomes (1)

  • Durability of the device component implant

    Assessment of the SI device component will be made at specified intervals using x-rays to check how long the device component can stay implanted with or without a revision surgery.

    From the implant procedure until 10 years post-operatively

Secondary Outcomes (6)

  • Change in range of motion (ROM) post-operatively at specified timepoints as compared to baseline

    From baseline (pre-operatively) until 10 years post-operatively

  • Change in ASES score post-operatively at specified timepoints as compared to baseline

    From baseline (pre-operatively) until 10 years post-operatively

  • Change in SANE score post-operatively at specified timepoints as compared to baseline

    From baseline (pre-operatively) until 10 years post-operatively

  • Change in PROMIS Global-10 score post-operatively at specified timepoints as compared to baseline

    From baseline (per-operatively) until 10 years post-operatively

  • Evaluation of radiographic images for radiolucent lines, implant stability and loosening

    From baseline (pre-operatively) until 10 years post-operatively

  • +1 more secondary outcomes

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult patients (at least 18 years of age) of any gender undergoing a shoulder arthroplasty for any diagnosis/condition with at least one SI Total Shoulder System component enrolled at participating sites

You may qualify if:

  • At least 18 years of age.
  • Plan to receive or has received a shoulder arthroplasty surgical procedure, with a minimum of one implanted Shoulder Innovations (SI) device component and be willing and able to complete post-operative visits as long as at least one SI device component remains implanted.
  • Able to provide informed consent prior to enrollment in the study (unless a waiver has been obtained).
  • Agree to and be able to consistently answer the specified Patient Reported Outcome Measures (PROM) pre-operatively and at each of the post-operative visits without the use of a translator.
  • Willing and able to comply with the requirements of the study protocol

You may not qualify if:

  • Participation in a clinical trial of an investigational drug or device that would confound the results of this trial. Participation in another observational registry is allowed provided there are no conflicting requirements to this trial.
  • Incarceration.
  • Any conditions, co-morbidities, restrictions, or obligations that would prohibit them from complying with the requirements of this study protocol.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

St. Vincent's Orthopedics

Birmingham, Alabama, 35205, United States

RECRUITING

California Pacific Orthopaedics

San Francisco, California, 94118, United States

RECRUITING

Western Orthopaedics

Denver, Colorado, 80222, United States

RECRUITING

Connolly Orthopedics

Bradenton, Florida, 34208, United States

RECRUITING

Georgia Bone and Joint

Newnan, Georgia, 30265, United States

RECRUITING

North Shore Physicians Group

Peabody, Massachusetts, 01960, United States

RECRUITING

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
10 Years
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 13, 2024

First Posted

December 31, 2024

Study Start

October 23, 2024

Primary Completion (Estimated)

December 1, 2039

Study Completion (Estimated)

December 1, 2039

Last Updated

January 22, 2026

Record last verified: 2026-01

Locations