Evaluating the Impact of Quitting Using Executive Function Strategy Training (QUEST) on Smoking Cessation in Homeless Young Adult Smokers

NCT06745154 | Completed

• 2 other identifiers: OSU-23119NCI-2024-04793
• Study Type: interventional
• Target: 27
• Locations: 1 country
• Sites: 1

Brief Summary

This clinical trial evaluates the impact of Quitting Using Executive Function Strategy Training (QUEST) on quitting smoking (cessation) in homeless young adult smokers with an acquired brain injury (ABI). Over 70% of youth and young adults experiencing homelessness (YYEH) smoke tobacco. More than half of YYEH who smoke have made at least one attempt to quit smoking but few use evidence-based methods to increase success. In addition, 9 out of 10 of these have an acquired brain injury which may have a negative impact on successful smoking cessation. QUEST may help homeless young adult smokers with an ABI quit smoking.

Conditions

Cigarette Smoking-Related Carcinoma

Outcome Measures

Primary Outcomes (4)

• Rate of executive function difficulties

  The number of times participants experience executive function difficulties with adhering to the Quit Line protocol will be recorded via survey questionnaires.

  Up to 8 weeks

• Factors impacting access to evidence-based treatment

  All factors reported by participants via survey questionnaires that impacted their ability to access Quit Line treatment will be recorded.

  Up to 8 weeks

• Contact with Quitline

  The number of contacts each participant had with the Quit Line throughout the study will be recorded via survey questionnaires.

  Up to 8 weeks

• Use of nicotine replacement therapy

  The number of times participants made use of nicotine replacement therapies throughout the length of the study will be recorded via survey questionnaires.

  Up to 8 weeks

Study Arms (1)

Prevention (QUEST)

EXPERIMENTAL

Patients receive access to the Ohio Tobacco Quitline, receive nicotine patches, gum, or lozenges for up to 8 weeks. Patients also participate in tobacco cessation counseling sessions for 5 sessions over 8 weeks. Patients additionally undergo cognitive assessment and nasal swab collection on study.

Procedure: Biospecimen Collection; Procedure: Cognitive Assessment; Other: Interview; Drug: Nicotine Replacement; Behavioral: Smoking Cessation Intervention; Other: Survey Administration; Other: Tobacco Cessation Counseling

Interventions

Biospecimen Collection PROCEDURE

Undergo nasal swab collection

Also known as: Biological Sample Collection, Biospecimen Collected, Specimen Collection

Prevention (QUEST)

Cognitive Assessment PROCEDURE

Undergo cognitive assessment

Prevention (QUEST)

Interview OTHER

Ancillary studies

Prevention (QUEST)

Nicotine Replacement DRUG

Given nicotine patches, gum, or lozenges

Also known as: Nicotine Replacement Therapy, NRT

Prevention (QUEST)

Smoking Cessation Intervention BEHAVIORAL

Receive access to the Ohio Tobacco Quit Line

Also known as: Smoking and Tobacco Use Cessation Interventions

Prevention (QUEST)

Survey Administration OTHER

Ancillary studies

Prevention (QUEST)

Tobacco Cessation Counseling OTHER

Participate in counseling sessions

Prevention (QUEST)

Eligibility Criteria

• Age: 18 Years - 24 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• years old
• Utilizing STAR House ( a drop-in center for youth and young adults experiencing homelessness) services
• Use of combustible tobacco product in the last week
• Willing to quit smoking in the next 30 days
• Acquired Brain Injury (ABI) (15 youth with and 15 without)
• CHATS will be used to determine ABI. Ask "C", "H" and "A" of the CHATS tool. If yes to C OR H and yes to A, that will be considered positive for ABI
• Have access to a phone
• Willing to use phone for QuitLine (QL) services
• Willing to enroll in Ohio Tobacco Quit Line
• Willing to share Ohio Tobacco Quit Line portal data with researchers
• Willing to provide biospecimens (exhaled air and nasal samples)
• Conversational English skills

Sponsors & Collaborators

• Ohio State University Comprehensive Cancer Center: lead

Study Sites (1)

Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210, United States

Location

Related Links

• The Jamesline

MeSH Terms

Interventions

Specimen Handling; Mental Status and Dementia Tests; Interviews as Topic; Nicotine Replacement Therapy; Smoking Devices

Intervention Hierarchy (Ancestors)

Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Investigative Techniques; Neuropsychological Tests; Psychological Tests; Behavioral Disciplines and Activities; Data Collection; Epidemiologic Methods; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health; Drug Therapy; Therapeutics; Manufactured Materials; Technology, Industry, and Agriculture

Study Officials

• Julianna Nemeth, PhD

  Ohio State University Comprehensive Cancer Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 17, 2024
• First Posted: December 20, 2024
• Study Start: June 26, 2023
• Primary Completion: August 30, 2023
• Study Completion: August 30, 2023
• Last Updated: December 20, 2024

Record last verified: 2024-12

Locations

US (1)