Success Metrics

Clinical Success Rate
61.2%

Based on 79 completed trials

Completion Rate
61%(79/129)
Active Trials
935(75%)
Results Posted
133%(105 trials)
Terminated
50(4%)

Phase Distribution

Ph not_applicable
113
9%
Ph phase_4
7
1%
Ph phase_1
333
27%
Ph phase_2
484
39%
Ph phase_3
118
9%
Ph early_phase_1
31
2%

Phase Distribution

364

Early Stage

484

Mid Stage

125

Late Stage

Phase Distribution1086 total trials
Early Phase 1First-in-human
31(2.9%)
Phase 1Safety & dosage
333(30.7%)
Phase 2Efficacy & side effects
484(44.6%)
Phase 3Large-scale testing
118(10.9%)
Phase 4Post-market surveillance
7(0.6%)
N/ANon-phased studies
113(10.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

45.4%

79 of 174 finished

Non-Completion Rate

54.6%

95 ended early

Currently Active

935

trials recruiting

Total Trials

1,249

all time

Status Distribution
Active(1030)
Completed(79)
Terminated(95)
Other(45)

Detailed Status

Recruiting619
Active, not recruiting316
Not yet recruiting92
Completed79
Terminated50
Withdrawn45

Development Timeline

Analytics

Development Status

Total Trials
1249
Active
935
Success Rate
61.2%
Most Advanced
Phase 4

Trials by Phase

Early Phase 131 (2.9%)
Phase 1333 (30.7%)
Phase 2484 (44.6%)
Phase 3118 (10.9%)
Phase 47 (0.6%)
N/A113 (10.4%)

Trials by Status

withdrawn454%
completed796%
active_not_recruiting31625%
not_yet_recruiting927%
unknown60%
recruiting61950%
suspended393%
enrolling_by_invitation30%
terminated504%

Recent Activity

Clinical Trials (1,249)

Showing 20 of 1,249 trialsScroll for more
NCT03866382Phase 2

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Recruiting
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT07532525Phase 1

Pomalidomide After CAR T-cell Therapy for the Treatment of Relapsed or Refractory CD19+ B-cell Leukemia or Lymphoma

Not Yet Recruiting
NCT06317662Phase 2

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Recruiting
NCT07349771Phase 2

Axatilimab Plus Standard of Care Therapy for the Prevention of Graft Versus Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Hematologic Cancer, ABRAXAS Trial

Not Yet Recruiting
NCT02726750

Observational Prospective Research Study In Monoclonal Gammopathies leadINg to Myeloma

Recruiting
NCT06568172Phase 3

Testing the Addition of an Immunotherapy Drug, Cemiplimab (REGN2810), Plus Surgery to the Usual Surgery Alone for Treating Advanced Skin Cancer

Recruiting
NCT06179303Phase 2

Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer

Recruiting
NCT07061977Phase 3

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Recruiting
NCT04665739Phase 2

Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors

Recruiting
NCT05642611Phase 3

Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy

Recruiting
NCT03634241Phase 2

Pembrolizumab in Preventing Lung Cancer in Patients With Stage I-II Non-Small Cell Lung Cancer or High-Risk Pulmonary Nodules, the IMPRINT-Lung Study

Completed
NCT06980038Phase 2

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

Recruiting
NCT03418038Phase 2

Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

Recruiting
NCT05828069Phase 2

A Study With Tovorafenib (DAY101) as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

Recruiting
NCT06015880Phase 1

Testing the Combination of Anti-cancer Drugs Mosunetuzumab, Polatuzumab Vedotin, and Lenalidomide for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Recruiting
NCT05256225Phase 3

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Recruiting
NCT07003295Phase 2

Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy

Recruiting
NCT05638295Phase 2

Testing the Use of AMG 510 (Sotorasib) and Panitumumab as a Targeted Treatment for KRAS G12C Mutant Solid Tumor Cancers (A ComboMATCH Treatment Trial)

Recruiting
NCT07224100Phase 2

Dose-Adjusted EPOCH With or Without Rituximab Plus Ponatinib for the Treatment of Newly-Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia/Lymphoma

Recruiting

Drug Details

Intervention Type
PROCEDURE
Total Trials
1,249