Success Metrics

Clinical Success Rate
59.3%

Based on 89 completed trials

Completion Rate
59%(89/150)
Active Trials
970(73%)
Results Posted
145%(129 trials)
Terminated
61(5%)

Phase Distribution

Ph phase_4
8
1%
Ph early_phase_1
31
2%
Ph not_applicable
126
10%
Ph phase_1
359
27%
Ph phase_2
515
39%
Ph phase_3
121
9%

Phase Distribution

390

Early Stage

515

Mid Stage

129

Late Stage

Phase Distribution1160 total trials
Early Phase 1First-in-human
31(2.7%)
Phase 1Safety & dosage
359(30.9%)
Phase 2Efficacy & side effects
515(44.4%)
Phase 3Large-scale testing
121(10.4%)
Phase 4Post-market surveillance
8(0.7%)
N/ANon-phased studies
126(10.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

45.2%

89 of 197 finished

Non-Completion Rate

54.8%

108 ended early

Currently Active

970

trials recruiting

Total Trials

1,325

all time

Status Distribution
Active(1084)
Completed(89)
Terminated(108)
Other(44)

Detailed Status

Recruiting637
Active, not recruiting333
Not yet recruiting110
Completed89
Terminated61
Withdrawn47

Development Timeline

Analytics

Development Status

Total Trials
1325
Active
970
Success Rate
59.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 131 (2.7%)
Phase 1359 (30.9%)
Phase 2515 (44.4%)
Phase 3121 (10.4%)
Phase 48 (0.7%)
N/A126 (10.9%)

Trials by Status

unknown50%
enrolling_by_invitation40%
withdrawn474%
active_not_recruiting33325%
recruiting63748%
terminated615%
completed897%
not_yet_recruiting1108%
suspended393%

Recent Activity

Clinical Trials (1,325)

Showing 20 of 1,325 trialsScroll for more
NCT02849496Phase 2

Testing Olaparib Either Alone or in Combination With Atezolizumab in BRCA Mutant Non-HER2-positive Breast Cancer

Active Not Recruiting
NCT06287775Phase 1

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

Recruiting
NCT07195734Phase 2

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

Recruiting
NCT06577441Phase 2

Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

Recruiting
NCT04514497Phase 1

Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer

Active Not Recruiting
NCT02954874Phase 3

Testing MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer

Active Not Recruiting
NCT07281430Not Applicable

Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S04)

Recruiting
NCT03141684Phase 2

Testing Atezolizumab Alone or Atezolizumab Plus Bevacizumab in People With Advanced Alveolar Soft Part Sarcoma

Active Not Recruiting
NCT07061951Phase 2

Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia

Recruiting
NCT05600894Phase 2

Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

Active Not Recruiting
NCT05711615Phase 1

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

Recruiting
NCT02496663Phase 1

Osimertinib and Necitumumab in Treating Patients With EGFR-Mutant Stage IV or Recurrent Non-small Cell Lung Cancer Who Have Progressed on a Previous EGFR Tyrosine Kinase Inhibitor

Active Not Recruiting
NCT04034927Phase 2

Testing the Addition of an Immunotherapy Drug, Tremelimumab, to the PARP Inhibition Drug, Olaparib, for Recurrent Ovarian, Fallopian Tube or Peritoneal Cancer

Active Not Recruiting
NCT03030378Phase 1

Pembrolizumab and Recombinant Interleukin-12 in Treating Patients With Solid Tumors

Active Not Recruiting
NCT05691491Phase 1

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

Recruiting
NCT05554380Phase 2

Study of Chemotherapy Plus Ipatasertib for People With Solid Tumors With PTEN/AKT Mutations, A ComboMATCH Treatment Trial

Suspended
NCT04963153Phase 1

Testing Combination Erdafitinib and Enfortumab Vedotin in Metastatic Bladder Cancer After Treatment With Chemotherapy and Immunotherapy

Active Not Recruiting
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT04071223Phase 2

Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, RadiCaL Study

Active Not Recruiting
NCT05987241Phase 2

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Recruiting

Drug Details

Intervention Type
PROCEDURE
Total Trials
1,325