Accuracy and External Validation of mREMS in Road Traffic Injuries

NCT06740409 | Completed DMC

• 2 other identifiers: UNCOMIRB20241214A017
• Study Type: observational
• Target: 292
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this prospective observational study is to assess the accuracy and external validation of the Modified Rapid Emergency Medicine Score (mREMS) in predicting outcomes for patients with road traffic injuries (RTIs) admitted to the emergency department of a hospital in Baghdad. The main questions it aims to answer are: How accurate is the mREMS in predicting the prognosis of road traffic injury patients? Does the mREMS provide reliable predictive value in a local context, specifically in Baghdad? Participants will: Be assessed using the mREMS upon admission to the emergency department. Have their clinical outcomes, including mortality, need for surgery, and length of stay, monitored throughout their hospital stay.

Conditions

Trauma

Keywords

MREMS

Outcome Measures

Primary Outcomes (2)

• In hospital mortality

  Mortality (death) during hospitalization.

  In-Hospital Phase (average of 7 days through discharge); Post-Discharge Follow-Up: Day 7, Day 30

• Accuracy Assessment of the modified Rapid Emergency Medicine Score (mREMS)

  range from 0 to 26. A higher mREMS score indicates a greater risk of mortality.

  the first 4 hours after ER admission

Secondary Outcomes (2)

• Length of Hospitalization

  Up to discharge, an average of 7 days

• Need for ICU Admission

  Up to discharge, an average of 7 days

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population will consist of adult patients aged 18 years and older presenting with road traffic injuries (RTIs) to the emergency department of a hospital in Baghdad. These patients will include individuals involved in motor vehicle collisions, motorcycle accidents, pedestrian-related incidents, and other road traffic-related traumas. Participants will be recruited within 4 hours of their injury to ensure timely assessment using the Modified Rapid Emergency Medicine Score (mREMS). Patients with a wide range of injury severities, from minor injuries to life-threatening trauma, will be included to evaluate the score's predictive accuracy across diverse clinical scenarios. The population will be representative of the local demographic and traffic conditions in Baghdad, ensuring the external validation of the mREMS score in this specific context.

You may qualify if:

• Patients with road traffic injuries (RTIs) admitted to the emergency department.
• Written informed consent provided by the patient or a legal representative (if the patient is unconscious or unable to provide consent).
• Patients presenting to the emergency department within 4 hours of the injury.
• Availability of complete physiological data for MREMS calculation.
• Patients whose clinical outcomes (e.g., mortality, length of hospital stay, need for intensive care) are available for follow-up and analysis.

You may not qualify if:

• Patients with injuries not related to road traffic accidents (e.g., falls, burns, or violence-related injuries).
• Pregnant women, due to the potential risk involved in the study and unique considerations in trauma care.
• Patients with pre-existing severe chronic conditions (e.g., end-stage renal disease, terminal cancer) that could severely affect outcomes.
• Patients who are unable or unwilling to provide informed consent.
• Patients who were transferred from another hospital.
• Incomplete or missing data for mREMS parameters.
• Patients who leave against medical advice (LAMA) or are discharged before outcome data can be collected.

Sponsors & Collaborators

• Al-Nahrain University: lead

Study Sites (1)

College of Medicine - Al-Nahrain University

Baghdad, Iraq

Location

Related Publications (4)

• Cassignol A, Markarian T, Cotte J, Marmin J, Nguyen C, Cardinale M, Pauly V, Kerbaul F, Meaudre E, Bobbia X. Evaluation and Comparison of Different Prehospital Triage Scores of Trauma Patients on In-Hospital Mortality. Prehosp Emerg Care. 2019 Jul-Aug;23(4):543-550. doi: 10.1080/10903127.2018.1549627. Epub 2019 Jan 7.

  PMID: 30457396 BACKGROUND

• Sewalt CA, Venema E, Wiegers EJA, Lecky FE, Schuit SCE, den Hartog D, Steyerberg EW, Lingsma HF. Trauma models to identify major trauma and mortality in the prehospital setting. Br J Surg. 2020 Mar;107(4):373-380. doi: 10.1002/bjs.11304. Epub 2019 Sep 10.

  PMID: 31503341 BACKGROUND

• Miller RT, Nazir N, McDonald T, Cannon CM. The modified rapid emergency medicine score: A novel trauma triage tool to predict in-hospital mortality. Injury. 2017 Sep;48(9):1870-1877. doi: 10.1016/j.injury.2017.04.048. Epub 2017 Apr 25.

  PMID: 28465003 RESULT

• Phunghassaporn N, Sukhvibul P, Techapongsatorn S, Tansawet A. Accuracy and external validation of the modified rapid emergency medicine score in road traffic injuries in a Bangkok level I trauma center. Heliyon. 2022 Dec 10;8(12):e12225. doi: 10.1016/j.heliyon.2022.e12225. eCollection 2022 Dec.

  PMID: 36568674 RESULT

MeSH Terms

Conditions

Wounds and Injuries

Study Officials

• Bashar A Abdulhassan, Assistant professor of surgery

  College Of Medicine - Nahrain University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: December 14, 2024
• First Posted: December 18, 2024
• Study Start: December 20, 2024
• Primary Completion: January 1, 2026
• Study Completion: January 15, 2026
• Last Updated: March 4, 2026

Record last verified: 2026-03

Data Sharing

• IPD Sharing: Will not share

Locations

IR (1)