Evaluating the New Trauma Score (NTS) for Improved Mortality Prediction

NCT06732752 | Not Yet Recruiting DMC

• 2 other identifiers: UNCOMIRB20241210A009
• Study Type: observational
• Target: 177
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this prospective cohort study is to evaluate the predictive accuracy of the New Trauma Score (NTS), a modification of the Revised Trauma Score (RTS), in determining mortality outcomes among trauma patients admitted to the emergency department at Al-Kadhimiya Teaching Hospital, Iraq. The main questions it aims to answer are: Does the NTS provide a more accurate prediction of mortality than the RTS? Are there specific subgroups of trauma patients where the NTS demonstrates superior predictive utility compared to the RTS? Participants will: Be assessed using both the NTS and RTS upon admission to the emergency department. Have their clinical outcomes, including mortality, tracked throughout their hospital stay.

Conditions

Trauma

Keywords

RTS

Outcome Measures

Primary Outcomes (3)

• In hospital mortality

  Mortality (death) during hospitalization

  In-Hospital Phase (average of 7 days through discharge); Post-Discharge Follow-Up: Day 7, Day 30

• Accuracy Assessment of the New Trauma Score (NTS)

  The New Trauma Score (NTS) ranges from 3 to 23. Higher scores indicate better physiological status and lower mortality risk.

  the first 6 hours after ER admission

• Accuracy Assessment of the Revised Trauma Score (RTS)

  The total RTS score ranges from 0 to approximately 12, with lower scores indicating more severe injuries and a higher risk of mortality.

  the first 6 hours after ER admission

Secondary Outcomes (3)

• Length of Hospitalization

  Up to discharge, an average of 7 days

• Need for ICU Admission

  Up to discharge, an average of 7 days

• Need for Surgical Intervention

  Up to discharge, an average of 7 days

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

consist of trauma patients admitted to the emergency department (ED) of Al-Kadhimiya Teaching Hospital over the study period. This will include both male and female patients of various age groups who present with trauma-related injuries.

You may qualify if:

• All trauma patients (including blunt, penetrating, and traumatic brain injury) admitted to the emergency department.
• Patients presenting with varying degrees of trauma (mild to severe).
• Patients (or their legal representatives) who provide informed consent to participate in the study.
• Trauma patients admitted to the emergency department.
• Patients who are assessed using both the Revised Trauma Score (RTS) and the New Trauma Score (NTS) upon admission to the emergency department.

You may not qualify if:

• Patients under 18 years old.
• Pregnant women, due to the potential complications and challenges in trauma assessment.
• Patients who refuse to give consent to participate in the study or whose legal guardians refuse on their behalf.
• Trauma patients transferred from other hospitals.
• Patients with incomplete medical records or missing key data required for trauma score calculation.

Sponsors & Collaborators

• Al-Nahrain University: lead

Study Sites (1)

College of Medicine - Al-Nahrain University

Baghdad, Iraq

Location

Related Publications (12)

• Manoochehry S, Vafabin M, Bitaraf S, Amiri A. A Comparison between the Ability of Revised Trauma Score and Kampala Trauma Score in Predicting Mortality; a Meta-Analysis. Arch Acad Emerg Med. 2019 Jan 15;7(1):e6. eCollection 2019 Winter.

  PMID: 30847441 BACKGROUND

• Indurkar SK Sr, Ghormade PS, Akhade S, Sarma B. Use of the Trauma and Injury Severity Score (TRISS) as a Predictor of Patient Outcome in Cases of Trauma Presenting in the Trauma and Emergency Department of a Tertiary Care Institute. Cureus. 2023 Jun 14;15(6):e40410. doi: 10.7759/cureus.40410. eCollection 2023 Jun.

  PMID: 37456404 BACKGROUND

• Mehmood A, Rowther AA, Kobusingye O, Ssenyonjo H, Zia N, Hyder AA. Delays in emergency department intervention for patients with traumatic brain injury in Uganda. Trauma Surg Acute Care Open. 2021 Aug 26;6(1):e000674. doi: 10.1136/tsaco-2021-000674. eCollection 2021.

  PMID: 34527810 BACKGROUND

• MacKenzie EJ, Rivara FP, Jurkovich GJ, Nathens AB, Frey KP, Egleston BL, Salkever DS, Scharfstein DO. A national evaluation of the effect of trauma-center care on mortality. N Engl J Med. 2006 Jan 26;354(4):366-78. doi: 10.1056/NEJMsa052049.

  PMID: 16436768 BACKGROUND

• Nirula R, Maier R, Moore E, Sperry J, Gentilello L. Scoop and run to the trauma center or stay and play at the local hospital: hospital transfer's effect on mortality. J Trauma. 2010 Sep;69(3):595-9; discussion 599-601. doi: 10.1097/TA.0b013e3181ee6e32.

  PMID: 20838131 BACKGROUND

• Bachani AM, Peden M, Gururaj G, Norton R, Hyder AA. Road Traffic Injuries. In: Mock CN, Nugent R, Kobusingye O, Smith KR, editors. Injury Prevention and Environmental Health. 3rd edition. Washington (DC): The International Bank for Reconstruction and Development / The World Bank; 2017 Oct 27. Chapter 3. Available from http://www.ncbi.nlm.nih.gov/books/NBK525212/

  PMID: 30212112 BACKGROUND

• Byass P, de Courten M, Graham WJ, Laflamme L, McCaw-Binns A, Sankoh OA, Tollman SM, Zaba B. Reflections on the global burden of disease 2010 estimates. PLoS Med. 2013;10(7):e1001477. doi: 10.1371/journal.pmed.1001477. Epub 2013 Jul 2.

  PMID: 23843748 BACKGROUND

• van Breugel JMM, Niemeyer MJS, Houwert RM, Groenwold RHH, Leenen LPH, van Wessem KJP. Global changes in mortality rates in polytrauma patients admitted to the ICU-a systematic review. World J Emerg Surg. 2020 Sep 30;15(1):55. doi: 10.1186/s13017-020-00330-3.

  PMID: 32998744 BACKGROUND

• Damulira J, Muhumuza J, Kabuye U, Ssebaggala G, Wilson ML, Barnighausen T, Lule H. New Trauma Score versus Kampala Trauma Score II in predicting mortality following road traffic crash: a prospective multi-center cohort study. BMC Emerg Med. 2024 Jul 29;24(1):130. doi: 10.1186/s12873-024-01048-0.

  PMID: 39075406 RESULT

• Farzan N, Foroghi Ghomi SY, Mohammadi AR. A retrospective study on evaluating GAP, MGAP, RTS and ISS trauma scoring system for the prediction of mortality among multiple trauma patients. Ann Med Surg (Lond). 2022 Mar 28;76:103536. doi: 10.1016/j.amsu.2022.103536. eCollection 2022 Apr.

  PMID: 35495411 RESULT

• Chawda MN, Hildebrand F, Pape HC, Giannoudis PV. Predicting outcome after multiple trauma: which scoring system? Injury. 2004 Apr;35(4):347-58. doi: 10.1016/S0020-1383(03)00140-2.

  PMID: 15037369 RESULT

• Jeong JH, Park YJ, Kim DH, Kim TY, Kang C, Lee SH, Lee SB, Kim SC, Lim D. The new trauma score (NTS): a modification of the revised trauma score for better trauma mortality prediction. BMC Surg. 2017 Jul 3;17(1):77. doi: 10.1186/s12893-017-0272-4.

  PMID: 28673278 RESULT

MeSH Terms

Conditions

Wounds and Injuries

Study Officials

• Mohammad A. Hamdawi, Lecturer of general surgery

  College Of Medicine - Nahrain University

  STUDY DIRECTOR

Central Study Contacts

Abdul-Ilah R. Khamis

CONTACT

+9647838571013; allaabed987@ced.nahrainuniv.edu.iq

Luma K Mohammed, MBChB,FIBMS/CM

CONTACT

+964770225676; lumakmohammed@nahrainuniv.edu.iq

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: December 10, 2024
• First Posted: December 13, 2024
• Study Start: April 28, 2025
• Primary Completion: June 10, 2025
• Study Completion: June 20, 2025
• Last Updated: March 18, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

IR (1)