Anterior Segment and Corneal Parameters in Keratoconus and High Myopic Astigmatism Using Schiempflug Imaging

NCT06739018 | Not Yet Recruiting

• 1 other identifier: pentacam parameters compare
• Study Type: observational
• Target: 66
• Locations: 1 country
• Sites: 2

Brief Summary

The purpose of this study was to compare Scheimpflug corneal tomography findings in keratoconus and high myopic astigmatic eyes, as well as to establish the parameters distinguishing keratoconus from high myopic astigmatism.

Conditions

Keratoconus; High Myopia

Outcome Measures

Primary Outcomes (1)

• overall corneal mean difference thickness between keratoconus and mopc astigmatism

  Scheimpflug imaging uses a revolving Scheimpflug camera to determine the front and back surfaces of the cornea, hence measuring the overall corneal mean difference thickness between keratoconus and mopc astigmatism as regarding central anterior chamber depth

  baseline

Study Arms (2)

keratoconic group

patients with keratoconus

Other: pentacam scheimpflug tomography

high myopic astigmatim group

patients with high myopic astigmatism

Other: pentacam scheimpflug tomography

Interventions

pentacam scheimpflug tomography OTHER

Pentacam tomography is not radiation-based. It uses Scheimpflug imaging, which involves a rotating camera that captures multiple images of the anterior segment of the eye. The system employs light-based technology to measure the front and back surfaces of the cornea, along with the anterior chamber and lens, creating a 3D model of the anterior eye structures. it uses light instead of ionizing radiation (like X-rays), it is considered safe and non-invasive for routine use in ophthalmology. * It was used to assess 23 parameters from topographic maps and 15 parameters from Belin-Ambrosio enhanced ectasia (BAD) display maps. * Parameters included keratometry readings, anterior and posterior sagittal curvature, corneal thickness, anterior chamber volume, and several indices from the BAD display map. * These parameters were analyzed to discriminate between keratoconus and high myopic astigmatism using Receiver Operating Characteristic (ROC) curves for diagnostic accuracy.

high myopic astigmatim group; keratoconic group

Eligibility Criteria

• Age: 15 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

The population represents individuals either have keratoconus or high mopic astigmatism and fit the inclusion and exclusion criteria to ensure proper comparison of corneal parameters .

You may qualify if:

• keratoconus patient
• virgin clear cornea with high myopic astigmatism
• normal cornea with high myopic astigmatism

You may not qualify if:

• patients had previous ocular surgery
• ocular diseases rather than keratoconus
• contact lens wearer
• corneal opacity and corneal dystrophy

Sponsors & Collaborators

• Assiut University: lead

Study Sites (2)

Assiut university

Asyut, Asyut Governorate, 71526, Egypt

Location

Assiut university

Asyut, 71515, Egypt

Location

Related Publications (1)

• Zaabaar E, Kyei S, Parkson Brew MAA, Boadi-Kusi SB, Assiamah F, Asiedu K. The utility of measures of anterior segment parameters of a Pentacam Scheimpflug tomographer in discriminating high myopic astigmatism from keratoconus. PLoS One. 2021 Dec 2;16(12):e0260648. doi: 10.1371/journal.pone.0260648. eCollection 2021.

  PMID: 34855828 BACKGROUND

MeSH Terms

Conditions

Keratoconus

Condition Hierarchy (Ancestors)

Corneal Diseases; Eye Diseases

Study Officials

• Momen Aly, lecturer

  Assiut University

  STUDY DIRECTOR

Central Study Contacts

youstena w saied, resident

CONTACT

02+01229887036; youstenasaied@gmail.com

Mohamed s abdalrahman, professor

CONTACT

+201222414233; mohamed66saad@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: DR

Study Record Dates

• First Submitted: November 27, 2024
• First Posted: December 18, 2024
• Study Start: December 1, 2024
• Primary Completion: October 1, 2025
• Study Completion: October 1, 2025
• Last Updated: December 18, 2024

Record last verified: 2024-12

Locations

EG (2)