Key Insights

Highlights

Success Rate

85% trial completion

Published Results

15 trials with published results (6%)

Research Maturity

115 completed trials (44% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

7.6%

20 terminated out of 263 trials

Success Rate

85.2%

-1.4% vs benchmark

Late-Stage Pipeline

12%

31 trials in Phase 3/4

Results Transparency

13%

15 of 115 completed with results

Key Signals

15 with results85% success20 terminated

Data Visualizations

Phase Distribution

179Total
Not Applicable (105)
Early P 1 (2)
P 1 (12)
P 2 (29)
P 3 (26)
P 4 (5)

Trial Status

Completed115
Unknown67
Recruiting28
Terminated20
Active Not Recruiting11
Not Yet Recruiting11

Trial Success Rate

85.2%

Benchmark: 86.6%

Based on 115 completed trials

Clinical Trials (263)

Showing 20 of 20 trials
NCT04598932Enrolling By InvitationPrimary

Corneal Biomechanical Analysis Using Brillouin Microscopy

NCT07841470Phase 2RecruitingPrimary

Corneal Crosslinking for Treatment of Progressive Keratoconus or Corneal Ectasia

NCT03922542Phase 2CompletedPrimary

Comparison of Standard vs. Accelerated Corneal Crosslinking

NCT05019768Not ApplicableCompletedPrimary

Topo-pachimetric Accelerated Epi-On Cross-linking Compared to Dresden Protocol Using Riboflavin With Vitamin E TPGS

NCT06235567Phase 1Enrolling By InvitationPrimary

Dextenza Versus Topical Steroid Eye Drops for Postoperative Management Following Corneal Crosslinking

NCT07780890Recruiting

A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases

NCT04174209Not ApplicableCompletedPrimary

CHOICE OF SUBJECTIVE OCULAR REFRACTION TECHNIQUE AND CORNEAL TOPOGRAPHY OF KERATOCONUS

NCT04594512Not ApplicableActive Not RecruitingPrimary

Fresh Corneal Lenticule Implantation and Autologous Serum - Case Report

NCT04591587Not ApplicableEnrolling By InvitationPrimary

Corneal Lenticule Implantation in Keratoconus Disease With Relex Smile Surgery

NCT07559188Not ApplicableNot Yet RecruitingPrimary

Proof-of-Concept for a Novel Optical Aperture Contact Lens in Presbyopia and Keratoconus

NCT06818461Completed

Assessment of Corneal Biomechanical Properties Using Corvis ST and ECD Following LASIK, PRK, CXL, Veriflex IOL and Implantable Collamer Lens

NCT06100939Phase 3CompletedPrimary

Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus

NCT06100952Phase 3CompletedPrimary

Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus

NCT04418999Early Phase 1CompletedPrimary

Safety and Efficacy of Intracanalicular Dexamethasone Compared to Loteprednol Etabonate in Patients With Keratoconus

NCT00560651Active Not RecruitingPrimary

German Corneal Cross Linking Register

NCT07629557Phase 4RecruitingPrimary

Evaluate the Safety and Feasibility of Same-Day Bilateral Epithelium-On Corneal Cross-Linking for Keratoconus

NCT03030755Recruiting

Corneal Elastography and Patient Specific Modeling

NCT04517903Not ApplicableCompletedPrimary

Validation Study on Eye Rubbing Questionnaire in Patients With or Suspected of Having a Keratoconus (KC)

NCT07599020Not ApplicableNot Yet RecruitingPrimary

Measuring the Changes of the Intraocular Pressure After Corneal Cross Linking Using Corvis CT

NCT01604135Phase 3Active Not RecruitingPrimary

Collagen Crosslinking for Keratoconus - a Randomized Controlled Clinical Trial

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