Evaluation of Retinal Vascular Density in High Myopia Without Pathological Myopic Maculopathy Using OCTA .

NCT06596408 | Recruiting

• 1 other identifier: Vascular Density in high Myope
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Study aiming to evaluate Macular Vascular Density in High Myopes without pathological myopic maculopathy in outpatient clinic in Sohag teaching hospital using OCTA .

Conditions

High Myopia

Outcome Measures

Primary Outcomes (1)

• Outcome of evaluation of vascular density in high myopes

  Correlation between macular vascular density in high myopes and their : Uncorrected visual acuity in diopters . Best corrected visual acuity in diopters . Spherical equivalent refraction that measured through this equivalent (spherical error + 1/2 cylindrical error ) . Central macular thickness in micrometers . To see how does ischemia affects vision in high myopes .

  6 month

Study Arms (1)

High Myopes of spherical error -6 and more .

EXPERIMENTAL

About 50 participants with high myopia will undergo evaluation of their macular vascular density using OCTA and also central macular thickness using OCT.

Other: optical coherence tomography angiography

Interventions

optical coherence tomography angiography OTHER

OCTA will be used to evaluate the macular vascular density and to exclude patients with pathological myopic maculopathy

High Myopes of spherical error -6 and more .

Eligibility Criteria

• Age: 15 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• All myopic patients with axial high myopia (-6 spherical refractive error or more) of different age groups .

You may not qualify if:

• History of other any ocular diseases , systemic diseases that may affect the ocular circulation .
• Previous intraocular surgery or ocular injury .
• Any patient with pathological myopic maculopathy as epiretinal membrane, foveoschisis, macular holes, lamellar holes, Lacquers cracks, choroidal neovascularization and retinal atrophy .

Sponsors & Collaborators

• Sohag University: lead

Study Sites (1)

Sohag University

Sohag, Sohag Governorate, 82524, Egypt

RECRUITING

Study Officials

• Adham Salah Mohammed, lecturer

  Sohag University

  STUDY CHAIR

Central Study Contacts

Sara Magdy Mohammed, Master degree

CONTACT

00201096507733; saramagdy@med.sohag.edu.eg

Islam Awny Ahmed, Ass. Prof

CONTACT

00201006429637

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: August 30, 2024
• First Posted: September 19, 2024
• Study Start: September 11, 2024
• Primary Completion: September 1, 2025
• Study Completion: October 1, 2025
• Last Updated: September 19, 2024

Record last verified: 2024-09

Locations

EG (1)