Chronic Kidney Disease in Pregnant Females

NCT06738069 | Not Yet Recruiting

• 1 other identifier: CKD in pregnancy
• Study Type: observational
• Target: 497
• Locations: 0 countries
• Sites: N/A

Brief Summary

Screening of Chronic Kidney Disease among pregnant women for early detection

Conditions

CKD

Outcome Measures

Primary Outcomes (1)

• Percentage of CKD among pregnant women attending antenatal care who came to outpatient clinic at the Women's Health Hospital and Nephrology Outpatient Clinic at Assiut University Hospitals

  Through study completion, an average of 3 years

Secondary Outcomes (1)

• Causes of CKD among pregnant women attending antenatal care who came to Outpatient clinic at the Women's Health Hospital and Nephrology Outpatient Clinic at assuit University Hospitals

  Through study completion, an average of 3 years

Study Arms (2)

Pregnant female with CKD

Pregnant female Newly discovered as chronic kidney disease by our study.inclusion criteria including age 18 or above who accept to precipitate this study.. exclusion criteria including female actually known as CKD and female refusing to precipitate in our study... this female confirmed as CKD by positive Alb/Cr ratio in 2 occasions with 3 months duration in between

Other: Participants are not assigned an intervention as a part of the study

Healthy pregnant female

Pregnant female without ckd and Alb /Cr ratio was negative

Other: Participants are not assigned an intervention as a part of the study

Interventions

Participants are not assigned an intervention as a part of the study OTHER

Participants are not assigned an intervention as a part of the study

Healthy pregnant female; Pregnant female with CKD

Eligibility Criteria

• Age: 18 Years - 50 Years
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The study population will consist of pregnant women aged 18 years and older who present to Assiut University Hospitals for routine antenatal care or are admitted for delivery. We will include women from all trimesters of pregnancy who can provide informed consent. Exclusion criteria will encompass those with a diagnosis of acute kidney injury, a history of kidney transplantation, or chronic conditions that may confound CKD assessment unless specifically included in the study. We aim to recruit a total coverage for one year from October 2024 to September 2025. This study will provide valuable insights into the frequency of chronic kidney disease among pregnant women in this setting.

You may qualify if:

• all pregnant women at antenatal care who came to Outpatient clinic at the Women's Health Hospital and Nephrology Outpatient Clinic at Assiut University Hospitals
• At age of 18 yrs old or above . -Who accept to participate with this study

You may not qualify if:

• Pregnant women who are known CKD.
• Pregnant women refuse to participate with this study .
• Pregnant women with Acute Kidney Injury .

Sponsors & Collaborators

• Assiut University: lead

Related Publications (4)

• Farrell DR, Vassalotti JA. Screening, identifying, and treating chronic kidney disease: why, who, when, how, and what? BMC Nephrol. 2024 Jan 25;25(1):34. doi: 10.1186/s12882-024-03466-5.

  PMID: 38273240 BACKGROUND

• Maule SP, Ashworth DC, Blakey H, Osafo C, Moturi M, Chappell LC, Bramham K, Milln J. CKD and Pregnancy Outcomes in Africa: A Narrative Review. Kidney Int Rep. 2020 May 26;5(8):1342-1349. doi: 10.1016/j.ekir.2020.05.016. eCollection 2020 Aug.

  PMID: 32775838 BACKGROUND

• Kovesdy CP. Epidemiology of chronic kidney disease: an update 2022. Kidney Int Suppl (2011). 2022 Apr;12(1):7-11. doi: 10.1016/j.kisu.2021.11.003. Epub 2022 Mar 18.

  PMID: 35529086 BACKGROUND

• Vinturache A, Khalil A, Glob. Libr. Women's me d., ISSN: 1756-2228; DOI 10.3843/GLOWM.411323

  BACKGROUND

Central Study Contacts

Rehab Makram Ibrahim, Doctor

CONTACT

+201014828702; roobroba@gmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctor

Study Record Dates

• First Submitted: December 13, 2024
• First Posted: December 17, 2024
• Study Start: December 1, 2024
• Primary Completion (Estimated): October 1, 2028
• Study Completion (Estimated): December 1, 2029
• Last Updated: December 17, 2024

Record last verified: 2024-09