A Retrospective Study of Prognostic Factors and Survival of Breast Cancer Patients with Brain Metastesis
1 other identifier
observational
60
0 countries
N/A
Brief Summary
The aim of the study is to to describe the pattern of BM in breast cancer patients, assess the prognostic significance of patient related-factors and to evaluate the efficacy of various treatment modalities. clinicopathological factors and prognostic factors that affect the occurrence of brain metastases and which factors affect the survival after the occurrence of brain metastases remain to be identified . This may help identify patients at high risk for brain metastases and patients with poor prognosis after brain metastases, thus providing them with some preventive or therapeutic measures.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Jan 2025
Typical duration for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 4, 2024
CompletedFirst Posted
Study publicly available on registry
December 9, 2024
CompletedStudy Start
First participant enrolled
January 1, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
February 1, 2027
ExpectedDecember 9, 2024
December 1, 2024
1 year
December 4, 2024
December 4, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
overall survival time
Time from brain metasets diagnosis till death.
baseline
Study Arms (1)
breast cancer
breast cancer patients with -Radiological documentation of BM by computed tomography (CT) OR magnetic resonance imaging (MRI)
Eligibility Criteria
breast cancer patients with brain metasets
You may qualify if:
- Age \>18
- Histological proven breast cancer
- Radiological documentation of BM by computed tomography (CT) OR magnetic resonance imaging (MRI)
- Patients who had been followed up for at least 6 months.
You may not qualify if:
- Not histologically proven Breast cancer
- Patient without full medical data
- Those with previous or concurrent diagnosis of second primary malignancy
- Patients with leptomeningeal or dural metastases without co-existent parenchymal metastatic lesions
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Yamamoto M, Serizawa T, Higuchi Y, Sato Y, Kawagishi J, Yamanaka K, Shuto T, Akabane A, Jokura H, Yomo S, Nagano O, Aoyama H. A Multi-institutional Prospective Observational Study of Stereotactic Radiosurgery for Patients With Multiple Brain Metastases (JLGK0901 Study Update): Irradiation-related Complications and Long-term Maintenance of Mini-Mental State Examination Scores. Int J Radiat Oncol Biol Phys. 2017 Sep 1;99(1):31-40. doi: 10.1016/j.ijrobp.2017.04.037. Epub 2017 Aug 7.
PMID: 28816158BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- resident doctor at Clinical oncology department
Study Record Dates
First Submitted
December 4, 2024
First Posted
December 9, 2024
Study Start
January 1, 2025
Primary Completion
January 1, 2026
Study Completion (Estimated)
February 1, 2027
Last Updated
December 9, 2024
Record last verified: 2024-12