MRI Morphology of Femoral Notch in ACL Injury

NCT06707285 | Not Yet Recruiting

• 1 other identifier: MRI in ACL injury
• Study Type: observational
• Target: 72
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to investigate the association between femoral notch morphology, as assessed by MRI, and the risk of ACL injury

Conditions

ACL Injury

Keywords

ACL ,femoral notch

Outcome Measures

Primary Outcomes (1)

• Correlation between femoral notch morphology and incidence of ACL injury

  Identify the different types of femoral notch angle , shapes and calculate the notch width index and correlate these differences with the incidence of ACL injury

  Base line

Study Arms (1)

ACL injured group , non-injured group

Device: MRI

Interventions

MRI DEVICE

1.5T siemens

ACL injured group , non-injured group

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Study population will include adult patients with ACL injury that had previous knee MRI imaging with no history of previous knee surgery or any pathological condition affecting bone health.

You may qualify if:

• patient aged 18-50 years.
• diagnosed with an ACL injury and confirmed by MRI and age-matched controls.

You may not qualify if:

• age \<18 yo and \>50 years
• patients with previous knee surgeries
• congenital knee deformities
• systemic conditions affecting bone health

Sponsors & Collaborators

• Assiut University: lead

Related Publications (6)

• Huang M, Li Y, Li H, Liao C, Xu H, Luo X. Predictive effects of the intercondylar notch morphology on anterior cruciate ligament injury in males: A magnetic resonance imaging analysis. Medicine (Baltimore). 2020 Mar;99(10):e19411. doi: 10.1097/MD.0000000000019411.

  PMID: 32150091 BACKGROUND

• Micicoi G, Jacquet C, Khakha R, LiArno S, Faizan A, Seil R, Kocaoglu B, Cerciello S, Martz P, Ollivier M. Femoral and Tibial Bony Risk Factors for Anterior Cruciate Ligament Injuries Are Present in More Than 50% of Healthy Individuals. Am J Sports Med. 2021 Dec;49(14):3816-3824. doi: 10.1177/03635465211050421. Epub 2021 Oct 28.

  PMID: 34710345 BACKGROUND

• Gultekin MZ, Dincel YM, Keskin Z, Arslan S, Yildirim A. Morphometric risk factors effects on anterior cruciate ligament injury. Jt Dis Relat Surg. 2023;34(1):130-137. doi: 10.52312/jdrs.2023.910. Epub 2022 Dec 27.

  PMID: 36700274 BACKGROUND

• Misir A, Sayer G, Uzun E, Guney B, Guney A. Individual and Combined Anatomic Risk Factors for the Development of an Anterior Cruciate Ligament Rupture in Men: A Multiple Factor Analysis Case-Control Study. Am J Sports Med. 2022 Feb;50(2):433-440. doi: 10.1177/03635465211062594. Epub 2022 Jan 12.

  PMID: 35019732 BACKGROUND

• Pradhan P, Kaushal SG, Kocher MS, Kiapour AM. Development of Anatomic Risk Factors for ACL Injuries: A Comparison Between ACL-Injured Knees and Matched Controls. Am J Sports Med. 2023 Jul;51(9):2267-2274. doi: 10.1177/03635465231177465. Epub 2023 Jun 13.

  PMID: 37310177 BACKGROUND

• Barnum MS, Boyd ED, Vacek P, Slauterbeck JR, Beynnon BD. Association of Geometric Characteristics of Knee Anatomy (Alpha Angle and Intercondylar Notch Type) With Noncontact ACL Injury. Am J Sports Med. 2021 Aug;49(10):2624-2630. doi: 10.1177/03635465211023750. Epub 2021 Jul 8.

  PMID: 34236929 BACKGROUND

MeSH Terms

Conditions

Anterior Cruciate Ligament Injuries

Condition Hierarchy (Ancestors)

Knee Injuries; Leg Injuries; Wounds and Injuries

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident doctor

Study Record Dates

• First Submitted: November 24, 2024
• First Posted: November 27, 2024
• Study Start: January 1, 2025
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): January 1, 2027
• Last Updated: November 27, 2024

Record last verified: 2024-11