Association Between Neuromuscular Parameters and Functional Assessment After ACL Reconstruction

NCT06524869 | Recruiting

• 1 other identifier: KASTLAB
• Study Type: observational
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

The anterior cruciate ligament (ACL) injury is common in athletes aged 18 to 35. ACL reconstruction (ACLR) aims to restore knee stability in the process of returning to sports. Post-surgical rehabilitation focuses on optimizing biomechanical parameters, with neuromuscular and functional tests assessing muscle strength, proprioception, and dynamic stability. Isokinetic allows the measurement of muscle strength symmetry and proprioception, while the single-leg hop and landing tasks assess functional stability and are predictive of sports resumption and injury prevention. Despite progress, concerns remain about neuromuscular factors impacting knee stability, especially during landings, which can increase the risk of secondary ACL injuries. This study proposes examining knee strength and proprioception using isokinetic dynamometry, alongside biomechanical assessments from functional tests, to explore their relationship to biomechanical features during landings, at 6-to-12 months post-ACL reconstruction. The hypothesis is that better muscle strength and proprioception correlate with improved knee control during landing tasks.

Conditions

ACL Injury

Outcome Measures

Primary Outcomes (4)

• Passive proprioceptive evaluation

  Measurement of knee proprioception by the passive repositioning technique (JPS, in degrees) on isokinetic dynamometer.

  One measurement during the visit at 6 to 12 months after surgery

• Strength

  Measurement of knee extensors and flexors peak strength (in newton.meter, Nm) on isokinetic dynamometer.

  One measurement during the visit at 6 to 12 months after surgery

• Single Hop test

  Measurement of knee position during landing from a single leg hop task

  One measurement during the visit at 6 to 12 months after surgery

• Single-leg landing task

  Measurement of knee position during landing from a 30-cm box

  One measurement during the visit at 6 to 12 months after surgery

Secondary Outcomes (3)

• Single Hop for Distance

  One measurement during the visit at 6 to 12 months after surgery

• ACL-RSI questionnaire (Anterior Cruciate Ligament-Return to Sport after Injury)

  One measurement during the visit at 6 to 12 months after surgery

• Landing Error Scoring System (LESS)

  One measurement during the visit at 6 to 12 months after surgery

Study Arms (1)

ACL reconstruction group

All sports patients who had a muscle evaluation at 6 to 12 months after ACLR since March 2024

Diagnostic Test: Isokinetic neuromuscular assessment

Interventions

Isokinetic neuromuscular assessment DIAGNOSTIC_TEST

All sports patients who had a muscle evaluation in addition to functional testing at 6-12 months after ACLR since March 2024

ACL reconstruction group

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

All sports patients included in the sport medicine follow-up protocole with isokinetic muscular assessment at 6-12 months after ACL reconstruction surgery since March 2024 in the sports medicine department (Return To Sport Process)

You may qualify if:

• Adult patients, aged 18-40, who have undergone a first ACL reconstruction more than 6 months ago and are being followed in a sports medicine care pathway
• Affiliated with a health insurance plan
• Information form: Non-objection to the use of data for research purposes

You may not qualify if:

• Previous ligament surgery of the lower limbs prior to ACL reconstruction
• Complex ligament injury (lateral ligaments, posterior cruciate ligament)
• Recent muscle injuries
• History of injury to the uninjured knee
• Pregnant woman
• Neurological history with residual effects or taking medication that affects balance/coordination
• Inability to perform a muscular assessment
• Postoperative complications (deep vein thrombosis, sepsis, stiffness/arthrofibrosis)

Sponsors & Collaborators

• University Hospital, Caen: lead

Study Sites (1)

CHU Caen Normandie

Caen, 14000, France

RECRUITING

Related Publications (1)

• Faivre O, Prum G, Hulet C, Drigny J. Improved hamstring strength and knee position sense are associated with enhanced landing mechanics after anterior cruciate ligament reconstruction. J ISAKOS. 2025 Jun;12:100858. doi: 10.1016/j.jisako.2025.100858. Epub 2025 Apr 5.

  PMID: 40194659 DERIVED

MeSH Terms

Conditions

Anterior Cruciate Ligament Injuries

Condition Hierarchy (Ancestors)

Knee Injuries; Leg Injuries; Wounds and Injuries

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: July 24, 2024
• First Posted: July 29, 2024
• Study Start: March 10, 2024
• Primary Completion: July 24, 2024
• Study Completion: August 30, 2024
• Last Updated: July 29, 2024

Record last verified: 2024-07

Locations

FR (1)