Investigation of Validity and Reliability of the Minnesota Manual Dexterity Test in Patients With Multiple Sclerosis

NCT06704464 | Completed

• 1 other identifier: 1-MS-minnesota-reliability
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Many assessment tools have been developed and used to evaluate upper extremity functions in multiple sclerosis (MS) patients. While each test has its strengths and weaknesses, the most significant limitation of these tests is that only a limited number assess both hands simultaneously. On the other hand, most daily life activities require the coordinated use of both hands. In MS patients, bilateral impairments in hand functions can also be observed. Therefore, there is a need for bilateral assessment tools. Unlike many other assessment tools, the Minnesota Manual Dexterity Test (MMDT) allows for simultaneous evaluation of both hands. In addition to manual dexterity, it also assesses hand-eye coordination and gross motor skills. The MMDT consists of five subtests: placing, turning, displacing, single-hand turning and placing, and two-hand turning and placing. The validity of the MMDT has also been examined in MS patients. Our study aims to evaluate the reliability and validity of the MMDT in MS patients. The cutoff times that best distinguish individuals with MS from healthy individuals will also be examined. The study aims to systematically and thoroughly evaluate the MMDT, establish it as a valid and reliable method for MS patients, and provide a new perspective on assessing hand functions.

Conditions

Multiple Sclerosis

Keywords

Minnesota manual dexterity; reliability; validity; multiple sclerosis; hand function

Outcome Measures

Primary Outcomes (2)

• Minnesota Manual Dexterity Test

  The Minnesota Manual Dexterity Test (MMDT) is a performance test designed to evaluate hand functions and hand-eye coordination both unilaterally and bilaterally, higher scores mean a worse outcome.

  baseline (on the predetermined assessment day)

• Minnesota Manual Dexterity Test-second

  The Minnesota Manual Dexterity Test (MMDT) is a performance test designed to evaluate hand functions and hand-eye coordination both unilaterally and bilaterally, higher scores mean a worse outcome.

  the second assessment will be conducted after the seven days

Secondary Outcomes (4)

• 9-Hole Peg Test

  baseline (on the predetermined assessment day)

• ABILHAND

  baseline (on the predetermined assessment day)

• The Jebsen Hand Function Test

  baseline (on the predetermined assessment day)

• The Expanded Disability Status Scale

  baseline (on the predetermined assessment day)

Study Arms (2)

Test Group

Patients with Multiple Sclerosis

Other: Manual Dexterity; Other: disability level

Control Group

healthy controls

Other: Manual Dexterity (only MMDT)

Interventions

Manual Dexterity OTHER

Individuals who meet the inclusion criteria will be evaluated for manual dexterity using MMDT, 9-HPT, ABILHAND, and JTHFT.

Test Group

Manual Dexterity (only MMDT) OTHER

Individuals who meet the inclusion criteria will be evaluated for manual dexterity using MMDT on a predetermined day.

Control Group

disability level OTHER

Individuals who meet the inclusion criteria will be evaluated for disability level using EDSS

Test Group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients with Multiple Sclerosis who apply to Sivas Cumhuriyet University, Department of Physiotherapy and Rehabilitation will be invited to this study.

You may qualify if:

• Age at least 18 years,
• Neurologist-diagnosed Multiple Sclerosis,
• Expanded Disability Status Scale (EDSS) score between 0-6.5
• No MS exacerbation within the last 3 months,
• Use of stable medication in the last 3 months.

You may not qualify if:

• Having any vision, hearing or perception problems that may affect the research results,
• Having an orthopedic problem that may affect manual skills in the upper extremity,
• Having a cardiovascular, pulmonary disorder

Sponsors & Collaborators

• Gazi University: lead
• Cumhuriyet University: collaborator

Study Sites (1)

Sivas Cumhuriyet Üniversity

Sivas, Turkey (Türkiye)

Location

Related Publications (2)

• Celik RGG. Upper Extremity Capability Tests in Multiple Sclerosis. Noro Psikiyatr Ars. 2018;55(Suppl 1):S54-S57. doi: 10.29399/npa.23338.

  PMID: 30692857 RESULT

• Hervault M, Balto JM, Hubbard EA, Motl RW. Reliability, precision, and clinically important change of the Nine-Hole Peg Test in individuals with multiple sclerosis. Int J Rehabil Res. 2017 Mar;40(1):91-93. doi: 10.1097/MRR.0000000000000209.

  PMID: 28059944 RESULT

MeSH Terms

Conditions

Multiple Sclerosis

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor

Study Record Dates

• First Submitted: November 18, 2024
• First Posted: November 26, 2024
• Study Start: November 28, 2024
• Primary Completion: January 25, 2025
• Study Completion: January 25, 2025
• Last Updated: March 18, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)