Comparison of Different Training Programs on Cognitive Function

NCT06682741 | Enrolling By Invitation

• 1 other identifier: 433/24
• Study Type: interventional
• Target: 500
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of the project is to identify the most effective exercise modalities in terms of neuroprotective effects and FP improvement. Hypothesis: Dancing will increase BDNF, GDNF and CLU levels to a greater extent than traditional forms of AF, resulting in significantly greater improvements in FP in subjects aged ≥ 60 years. The study will involve 60 women aged ≥ 60 years, randomly and equitably assigned to training groups (i.e., resistance training using body weight, dance) and a control group (i.e., a group of physically inactive women). Methodology: Participants: 60 women aged ≥ 60 randomly and equally assigned to training groups (Dance and Resistance training) and a control group (i.e., physically inactive women) Scientists will compare the impact of different forms of physical activity on cognitive functions

Conditions

Mild Cognitive Impairment (MCI)

Keywords

physical activity; neurotrophins; neuroprotection; cognitive function; MCI

Outcome Measures

Primary Outcomes (1)

• tle level of cognitive functions

  Cognitive functioning is assessed using the standardized MoCA test, which has a maximum score of 30 points. A score of 26 or higher is considered normal

  before and after 12 months of interventions

Secondary Outcomes (1)

• blood markers

  before and after 12 months of intervention

Study Arms (1)

excercise

EXPERIMENTAL

supervised exercise training; twice a week for 12 months

Other: Exercise

Interventions

Exercise OTHER

supervised exercise training; twice a week for 12 months

excercise

Eligibility Criteria

• Age: 50 Years+
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• women

You may not qualify if:

• previous diagnoses of cardiovascular diseases

Sponsors & Collaborators

• Poznan University of Physical Education: lead

Study Sites (1)

Poznan University of Physical Education

Poznan, Poland, 61-871, Poland

Location

MeSH Terms

Conditions

Cognitive Dysfunction; Motor Activity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders; Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Joanna Ratajczak, PhD

  Poznan University of Physical Education

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 18, 2024
• First Posted: November 12, 2024
• Study Start: September 17, 2024
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): June 30, 2027
• Last Updated: November 12, 2024

Record last verified: 2024-09

Data Sharing

• IPD Sharing: Will not share

Locations

PL (1)