Acceptability, Usability and Preliminary Effectiveness of ChatGPT in Increasing Seasonal Influenza Vaccination Uptake Among Older Adults in Hong Kong

NCT06679647 | Not Yet Recruiting

• 1 other identifier: SIV_ChatGPT
• Study Type: interventional
• Target: 50
• Locations: 0 countries
• Sites: N/A

Brief Summary

In this project, we will train a ChatGPT to provide real-time answers to questions related to the SIV for older adults in Hong Kong. This study aims to evaluate the usability, acceptability, and preliminary effectiveness of the ChatGPT among 50 community-living people aged 65 years and above in Hong Kong. The primary objectives are to evaluate the usability and acceptability (including the extent of usage and subjective experiences of behavioural, cognitive, and affective engagement) of the ChatGPT at the end of the 4-week intervention period (T1). The secondary objectives are to evaluate the following conditions measured at T1, as compared to those measured at baseline (T0):

1. 1.Self-reported uptake of SIV in the past month.
2. 2.Changes in behavioural intention to receive SIV for the approaching flu season.
3. 3.Changes in knowledge and attitudes related to SIV.

Conditions

Behavior Change Interventions

Outcome Measures

Primary Outcomes (3)

• Perceived usability

  Perceived usability assessed by the validated Chinese version of the 10-item Perceived Usability Scale (SUS)

  1 month

• Extent of usage documented by the ChatGPT

  Extent of usage documented by the ChatGPT

  1 month

• Subjective experiences related to behavioural, cognitive, and affective engagement

  Subjective experiences related to behavioural, cognitive, and affective engagement measured by the validated Twente Engagement with eHealth Technologies Scale (TWEETS)

  1 month

Study Arms (1)

ChatGPT group

EXPERIMENTAL

Participants will be invited to use a trained ChatGPT which answers questions related to seasonal influenza vaccination. The functions can be used repeatedly throughout the intervention period (4 weeks), and participants will be free to spend as much time as they want on such functions.

Behavioral: Access to a trained ChatGPT

Interventions

Access to a trained ChatGPT BEHAVIORAL

Participants will be invited to use a trained ChatGPT which answers questions related to seasonal influenza vaccination. The functions can be used repeatedly throughout the intervention period (4 weeks), and participants will be free to spend as much time as they want on such functions.

ChatGPT group

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• Aged ≥65 years;
• Possession of a Hong Kong ID;
• Able to speak and comprehend Cantonese;
• Have a smartphone with internet access;
• Have not taken SIV for the approaching flu season.

You may not qualify if:

• With diagnosis of cognitive impairment or dementia;
• Either blindness or deafness;
• With known contraindications to the SIV as indicated by the Hong Kong Centre for Health Protection

Sponsors & Collaborators

• Chinese University of Hong Kong: lead

Related Publications (1)

• Wang Z, Tsang TH, Yu FY, Fang Y, Chen S, Sun F, Mo PKH, Wong KC. Effectiveness, Usability, and Acceptability of ChatGPT With Retrieval-Augmented Generation (SIV-ChatGPT) in Increasing Seasonal Influenza Vaccination Uptake Among Older Adults: Quasi-Experimental Study. J Med Internet Res. 2025 Sep 8;27:e76849. doi: 10.2196/76849.

  PMID: 40921067 DERIVED

Study Officials

• Zixin Wang, PhD

  Chinese University of Hong Kong

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Zixin Wang, PhD

CONTACT

+852 22528740; wangzx@cuhk.edu.hk

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: November 6, 2024
• First Posted: November 7, 2024
• Study Start: December 1, 2024
• Primary Completion: March 31, 2025
• Study Completion: March 31, 2025
• Last Updated: November 7, 2024

Record last verified: 2024-11

Data Sharing

• IPD Sharing: Will not share