Effect of Wet Cupping Versus Moderate Intensity Aerobic Exercise on Inflammatory Markers in Diabetic Patients

NCT06667648 | Completed DMC

• 1 other identifier: Physical Therapy 2024
• Study Type: interventional
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

Among all pro-inflammatory biomarkers, TNF-α first recognized to be involved in the pathenogenesis of insulin resistance, and glucose-related abnormalities that link to T2DM. TNF-α plays a vital role in the overall pathophysiology of insulin resistance especially in males with greater body mass index as compared to that in the females This trial aims to investigate the effect of wet cupping therapy versus moderate intensity aerobic exercise on inflammatory markers in diabetic patients

Conditions

Diabetes

Keywords

diabetes, cupping, aerobic excercise

Outcome Measures

Primary Outcomes (3)

• interleukin 6 concentrations

  Kits for blood sample to detect serum interleukin 6

  6 months

• blood sugar level mg/dl

  blood sample to determine blood sugar level

  6 months

• tumor necrosis factor percent

  kits to determine tumor necrosis factor alpha

  6 months

Study Arms (2)

Group (A)

NO INTERVENTION

) attended the program of walking on a treadmill machine for eight weeks according to the following parameters: - * Mode of exercise: aerobic exercise. * Intensity: according to heart rate (60-75% of maximum heart rate) MHR=220-age. * Heart rate: determined by the sensor of a treadmill. * Duration: 40-50 min per session. Each session consisted of 5-10 minutes of warming up exercise on a treadmill without increasing speed or intensity and the same for the cooling down phase

Group (B)

OTHER

Each cupping session takes about 30-40 min and can be conducted in five steps. The first step includes primary suction. In this phase, the therapist allocates specific points or areas for cupping and disinfects the area, which located at the upper back (opposite to C7), Para spinal and below scapula. A cup with a suitable size is placed on the selected site and sucked the air inside the cup by manual suction. Then the cup was applied to the skin and left for a period of 3 to 5 min. The second step is about puncturing. Puncturing with a needle to get out of blood the third step is about suction and bloodletting. The cup is placed back on the skin using the similar procedure described above for 3 to 5 min. The fourth step includes the removal of the cup, followed by the fifth step which includes dressing the area after cleaning and disinfecting with FDA-approved skin disinfectant.

Procedure: cupping session

Interventions

cupping session PROCEDURE

Each cupping session takes about 30-40 min and can be conducted in five steps. The first step includes primary suction. In this phase, the therapist allocates specific points or areas for cupping and disinfects the area, which located at the upper back (opposite to C7), Para spinal and below scapula. A cup with a suitable size is placed on the selected site and sucked the air inside the cup by manual suction. Then the cup was applied to the skin and left for a period of 3 to 5 min. The second step is about puncturing. Puncturing with a needle to get out of blood the third step is about suction and bloodletting. The cup is placed back on the skin using the similar procedure described above for 3 to 5 min. The fourth step includes the removal of the cup, followed by the fifth step which includes dressing the area after cleaning and disinfecting with FDA-approved skin disinfectant.

Group (B)

Eligibility Criteria

• Age: 30 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• had diabetes more than 10 years ago
• body mass index of 25 to 29.9 Kg/m2

You may not qualify if:

• Hepatic diseases, Cancer patients, Renal failure patients, Orthopedic problems or fractures of extremities, hypertensive patients, and Neurological problems

Sponsors & Collaborators

• Deraya University: lead

MeSH Terms

Conditions

Diabetes Mellitus

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: associate professor of pharmaceutics and clinical pharmacy

Study Record Dates

• First Submitted: October 16, 2024
• First Posted: October 31, 2024
• Study Start: March 15, 2014
• Primary Completion: September 11, 2024
• Study Completion: October 15, 2024
• Last Updated: February 7, 2025

Record last verified: 2025-02