Evaluation of the Effect of Low Level Laser Therapy on Crestal Bone Changes and Secondary Stability Around Delayed Implant

NCT06666062 | Active Not Recruiting

• 1 other identifier: 1211
• Study Type: interventional
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

Although implant survival and success rates are prominent, there is still progress to be made in both survival and success rates, as well as in improving implant stability at implant placement in order to accomplish osseo-integration without significantly reducing peri-implant marginal bone. Low-level laser therapy (LLLT) has been postulated in studies looking into enhancing implant stability. Understanding the effect of LLLT on bone remodeling is crucial to knowing whether LLLT will enhance implant-bone interaction. LLLT prompts vascularization of the bone defect site and also stimulates osteoblasts, which can facilitate recovery of hard tissue. In addition, it has been recently reported that LLLT has positive effects in ossification and osseo-integration of dental implants.

Conditions

Laser Effect Around Dental Implant

Outcome Measures

Primary Outcomes (1)

• Radiographic evaluation of crestal bone changes

  3 months

Secondary Outcomes (1)

• Evaluation of the secondary implant stability using implant stability quotient ( ISQ ) in response to LLLT.

  3 months

Study Arms (2)

Study group

ACTIVE COMPARATOR

Other: implant placement and low level laser therapy

Control group

PLACEBO COMPARATOR

Procedure: implant placement

Interventions

implant placement and low level laser therapy OTHER

Laser biomodulation with low level laser therapy around delayed implant

Study group

implant placement PROCEDURE

Delayed implant placement restoring missed tooth

Control group

Eligibility Criteria

• Age: 20 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy adult patients as evidenced by Burkett's oral medicine health history questionnaire (18).
• Both genders. 3- Age from 20 -50 years old. 4- History of extraction\< 6 months. 5- Site specific upper esthetic zone from right second premolar to left second premolar.

You may not qualify if:

• Patients taking drugs affecting bone metabolism for the past six months. eg. cyclosporine, methotrexate, synthetic retinoids
• Smokers
• Pregnancy and lactation
• Patients with periodontal or periapical infections.
• Vertical and horizontal root fracture
• Mentally retarded Patients.

Sponsors & Collaborators

• Lina Amr Talaat: lead

Study Sites (1)

Ain shams university

Cairo, 4531, Egypt

Location

MeSH Terms

Interventions

Low-Level Light Therapy

Intervention Hierarchy (Ancestors)

Laser Therapy; Therapeutics; Phototherapy

Study Officials

• Lina Amr Elsayed

  Ain Shams University

  PRINCIPAL INVESTIGATOR

• Lina Amr Elsayed, Master candidate

  Ain Shams University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: BDS, periodontology and implantology, Ain shams university Clinical demonstrator oral medicine, periodontology horus university

Study Record Dates

• First Submitted: October 29, 2024
• First Posted: October 30, 2024
• Study Start: March 1, 2023
• Primary Completion: May 1, 2024
• Study Completion: December 1, 2024
• Last Updated: October 30, 2024

Record last verified: 2024-10

Locations

EG (1)