Efficacy of Adding Neural Mobilization Techniques in Patients With Cervical Radiculopathy

NCT06663592 | Completed

• 1 other identifier: P.T.REC/012/005270
• Study Type: interventional
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this randomized controlled trial is to investigate the effects of adding slider neural mobilization technique compared to tensioner neural mobilization technique to conventional physical therapy treatment on pain, function, cervical range of motion, hand grip strength, and electrophysiological parameters of the median nerve in patients with cervical radiculopathy.

Conditions

Cervical Radiculopathy; Neuromobılızatıon; Median Nerve; Electromyography; Nerve Conduction

Outcome Measures

Primary Outcomes (7)

• Visual Analogue Scale

  to measure neck pain with score extended from 0 to 10, minimum score 0 (no pain), highest score 10 (worst pain).

  At baseline, to the end of treatment at 4 weeks.

• The Arabic Version Of Neck Disability Index

  to assess the level of disabilities in patients with neck pain, in % points.

  At baseline, to the end of treatment at 4 weeks.

• Cervical Range of Motion

  to measure the full cervical rotation using CROM device in degrees

  At baseline, to the end of treatment at 4 weeks.

• Hand Grip Strength

  to measure hand grip strength using hydraulic dynamometer, in kilogram.

  At baseline, to the end of treatment at 4 weeks.

• Nerve Conduction Study

  Motor conduction study for the median nerve, to measure conduction velocity (m/second), distal latency (ms), and amplitude(mV).

  At baseline, to the end of treatment at 4 weeks.

• F wave

  F wave for the median nerve to measure latency (ms).

  At baseline, to the end of treatment at 4 weeks.

• H-Reflex

  H-Reflex for the median nerve to measure latency (ms), amplitude (mV), H-R ratio (%).

  At baseline, to the end of treatment at 4 weeks.

Study Arms (3)

Control group A (conventional treatment)

ACTIVE COMPARATOR

Conventional treatment, including hot pack, stretching of the neck muscles, cervical isometrics exercise.

Other: Conventional treatment

Experimental group B (Tensioning neural mobilization with addition to conventional treatment)

EXPERIMENTAL

Median nerve neural tensioning mobilization with addition to conventional treatment

Other: Tensioner Neuro Dynamic Mobilization

Experimental group C (Sliding neural mobilization with addition to conventional treatment)

EXPERIMENTAL

Median nerve sliding neural mobilization with addition to conventional treatment

Other: Slider Neuro Dynamic Mobilization

Interventions

Conventional treatment OTHER

hot pack, stretching of the neck muscles, cervical isometrics exercise

Control group A (conventional treatment)

Tensioner Neuro Dynamic Mobilization OTHER

Median nerve tensioner neural mobilization with addition to conventional treatment

Experimental group B (Tensioning neural mobilization with addition to conventional treatment)

Slider Neuro Dynamic Mobilization OTHER

Median nerve neural sliding mobilization with addition to conventional treatment

Experimental group C (Sliding neural mobilization with addition to conventional treatment)

Eligibility Criteria

• Age: 30 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Current continuous or intermittent pain that has persisted for more than 3 months.
• Motor, reflex, and/or sensory changes in the upper limb.
• Both genders aged 30-50 years.
• Three positive special tests out of five as a predefined diagnostic criterion from the following tests: Upper Limb Neural Tension A (ULNT) test for the median nerve, Spurling's test, compression test, cervical distraction test, less than 60° cervical rotation towards the symptomatic side, and Valsalva maneuver.
• A motor nerve conduction study, F wave, and H reflex were performed in the involved limb to confirm CR.

You may not qualify if:

• History of surgical procedures for cervical or upper extremity.
• Clinical signs or symptoms of medical red flags (infection, cancer, and cardiac involvement).
• Patients with neck pain for signs and symptoms of serious pathology, upper cervical ligamentous insufficiency, unexplained cranial nerve dysfunction, and spinal fractures.
• Any systematic disease such as rheumatism and tuberculosis, cervical myelopathy, or multiple sclerosis.
• Systemic disease is known to cause generalized peripheral neuropathy, such as diabetes mellitus.
• Complete loss of sensation along the involved nerve root.
• Upper limb compression syndrome, such as thoracic outlet syndrome, carpal tunnel syndrome, and pronator syndrome.
• Pregnant woman.
• Patients who have received any physical therapy of the cervical region in the past 3 months.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Cairo university

Cairo, Cairo Governorate, Egypt

Location

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MeSH Terms

Conditions

Radiculopathy

Condition Hierarchy (Ancestors)

Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: October 21, 2024
• First Posted: October 29, 2024
• Study Start: November 15, 2024
• Primary Completion: March 15, 2025
• Study Completion: April 15, 2025
• Last Updated: April 9, 2026

Record last verified: 2026-04

Locations

EG (1)