Reflexology and Mulligan Mobilization for Knee Osteoarthritis

NCT06815016 | Not Yet Recruiting DMC

• 1 other identifier: P.T.REC/012/005479
• Study Type: interventional
• Target: 84
• Locations: 1 country
• Sites: 1

Brief Summary

to investigate the effect of adding Reflexlogy to mulligan mobilization and the conventional treatment for patients with Osteoarthritis knees

Conditions

Knee Osteoarthritis; Knee Osteoarthritis (Knee OA)

Keywords

Knee Osteoarthristis; reflexology; Mulligan's Mobilization

Outcome Measures

Primary Outcomes (1)

• visual analogue scale

  consists of a line, usually 10 cm long, ranging from no pain or discomfort (zero), to the worst pain that could possibly feel (10)

  one month

Secondary Outcomes (1)

• The Knee Injury and Osteoarthritis Outcome Score (KOOS)

  one month

Other Outcomes (1)

• Kinovea

  one month

Study Arms (4)

Reflexology and conventional

EXPERIMENTAL

treatment all patient with knee osteoarthritis three times per week

Other: reflexology and conventional

mulligan mobilization and conventional

EXPERIMENTAL

treatment all patient with knee osteoarthritis three times per week

Other: mulligan mobilization and conventional

Reflexology ,mulligan mobilization and conventional

EXPERIMENTAL

treatment all patient with knee osteoarthritis three times per week

Other: Reflexology ,mulligan mobilization and conventional; Other: mulligan mobilization and conventional

Conventional methods

EXPERIMENTAL

treatment all patient with knee osteoarthritis three times per week

Other: Conventional treatment

Interventions

Reflexology ,mulligan mobilization and conventional OTHER

Reflexology is a systematic practice in which applying some pressure to any particular points on the feet and hands give impacts on the health of related parts of the body as (Knee reflex point, Pituitary reflex point, Entire spine, Liver reflex area, Thyroid reflex area ) Mulligan's Mobilization with Movement (MWM) apply accessory gliding force combined with active movement as (Lateral glide MWM for flexion / extension, Medial glide MWM for flexion / extension, Self-medial glide MWM for knee flexion/extension: home exercise)

Reflexology ,mulligan mobilization and conventional

reflexology and conventional OTHER

Reflexology as (Knee reflex point, Pituitary reflex point, Entire spine, Liver reflex area, Thyroid reflex area ) and conventional methods as (Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy and exercises) treatment.

Reflexology and conventional

mulligan mobilization and conventional OTHER

Mulligan mobilization as (Lateral glide MWM for flexion / extension, Medial glide MWM for flexion / extension, Self-medial glide MWM for knee flexion/extension: home exercise) and conventional methods as (Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy and exercises) treatment.

Reflexology ,mulligan mobilization and conventional; mulligan mobilization and conventional

Conventional treatment OTHER

Conventional methods as (Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy and exercises) treatment.

Conventional methods

Eligibility Criteria

• Age: 40 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Age greater than or equal to 40 years.
• Body Mass Index ≤30 kg/m².
• All participants have Calcium Deficiency
• Osteoarthritis in mild and moderate stage not in the acute stage
• The subjects were chosen from both genders

You may not qualify if:

• Deep Vein Thrombosis
• Fractures
• Gangrena Patient
• Osteopenic Patient
• Lactating or pregnant women
• Cancer
• Neurological conditions.
• Patients with injury including; (lesions, sprain, open wounds, foot ulcer and or burn of the lower extremities), hemorrhage, epilepsy, irregular heartbeat.
• Vascular (Anticoagulant Therapy, Aortic Aneurysm)
• Neurological Deficits (multilevel PIVD, Cervical Myelopathy)
• Psychological Disorders.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Cairo University

Cairo, Egypt

Location

Related Publications (2)

• Bakir E, Baglama SS. The Effect of Foot Reflexology and Knee Massage With Black Cumin Seed Oil on Knee Osteoarthritis Symptoms. Holist Nurs Pract. 2026 Jan-Feb 01;40(1):56-65. doi: 10.1097/HNP.0000000000000714. Epub 2025 Nov 11.

  PMID: 39642267 BACKGROUND

• Bhagat M, Neelapala YVR, Gangavelli R. Immediate effects of Mulligan's techniques on pain and functional mobility in individuals with knee osteoarthritis: A randomized control trial. Physiother Res Int. 2020 Jan;25(1):e1812. doi: 10.1002/pri.1812. Epub 2019 Sep 10.

  PMID: 31502354 BACKGROUND

MeSH Terms

Conditions

Osteoarthritis, Knee

Interventions

Congresses as Topic; Musculoskeletal Manipulations

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Intervention Hierarchy (Ancestors)

Organizations; Health Care Economics and Organizations; Complementary Therapies; Therapeutics; Physical Therapy Modalities; Rehabilitation

Study Officials

• Noran A Elbehary, Professor of physical Therapy

  basic science department, faculty of physical therapy cairo university

  PRINCIPAL INVESTIGATOR

• Mariam O Grase, lecturer physical therapy

  basic science department, faculty of physical therapy cairo university

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Rania a nassar, master

CONTACT

01010618797; raniaanassar@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: demonstrator physical therapy

Study Record Dates

• First Submitted: February 3, 2025
• First Posted: February 7, 2025
• Study Start: February 20, 2025
• Primary Completion: February 20, 2026
• Study Completion: April 20, 2026
• Last Updated: February 7, 2025

Record last verified: 2025-02

Locations

EG (1)