Impact of Anxiety and Depression on Implicit and Explicit Memory Performance

NCT06663423 | Completed

• 1 other identifier: SDU-MEMORY-2024
• Study Type: observational
• Target: 27
• Locations: 1 country
• Sites: 1

Brief Summary

This study examines the effect of anxiety and depression on memory processes, focusing on implicit and explicit memory. Implicit memory involves unconscious recall, such as recognizing familiar words without effort, while explicit memory requires conscious recollection of specific information. The study aims to investigate whether individuals with depression and anxiety show differences in these types of memory, which may contribute to biases related to their emotional states. Participants were divided into three groups: individuals with depressive disorder, individuals with generalized anxiety disorder, and a control group with no emotional disorders. Each group was assessed using tasks designed to measure both implicit and explicit memory performance. The goal is to enhance understanding of memory biases in individuals with depression and anxiety, potentially supporting more targeted interventions.

Conditions

Major Depressive Disorder (MDD); Generalized Anxiety Disorder (GAD); Memory Bias; Implicit Memory; Explicit Memory

Keywords

Anxiety; Depression; Cognitive Bias; Memory Processing; Emotional Influence on Memory; Word Recognition Task; Mood-Congruent Memory; Psychological Disorders

Outcome Measures

Primary Outcomes (1)

• Explicit Memory Bias

  The primary outcome is to assess explicit memory bias by measuring word recognition in participants with depressive disorder, generalized anxiety disorder, and a control group. Word recognition accuracy and response times are evaluated to determine mood-congruent biases specific to each group.

  At a single time point during the experimental session, approximately 1 day

Secondary Outcomes (1)

• Implicit Memory Bias

  At a single time point during the experimental session, approximately 1 hour

Other Outcomes (1)

• Mood Congruence in Recognition Performance

  At a single time point during the experimental session, approximately 1 hour

Study Arms (3)

Group 1

Depressive Disorder group - 9 participants.

Group 2

Generalized Anxiety Disorder group - 9 participants.

Group 3

Control group - 9 participants.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

A sample of individuals from Tehran Institute of Psychiatry and Shahid Esmaili Clinic, including patients with depressive disorder, generalized anxiety disorder, and a control group of healthy individuals with no history of emotional disorders.

You may qualify if:

• Adults aged 18 years or older
• Individuals diagnosed with major depressive disorder (Group 1)
• Individuals diagnosed with generalized anxiety disorder (Group 2)
• Healthy individuals with no history of emotional disorders (Group 3)

You may not qualify if:

• History of neurological disorders
• Visual impairments
• Substance abuse or drug addiction
• Psychiatric hospitalizations unrelated to primary diagnosis (for Groups 1 and 2)

Sponsors & Collaborators

• Islamic Azad University, Sanandaj: lead

Study Sites (1)

Tehran Institute of Psychiatry and/or Shahid Esmaili Clinic.

Tehran, Tehran Province, 14176, Iran

Location

MeSH Terms

Conditions

Depressive Disorder, Major; Generalized Anxiety Disorder; Anxiety Disorders; Depression; Mental Disorders

Condition Hierarchy (Ancestors)

Depressive Disorder; Mood Disorders; Behavioral Symptoms; Behavior

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator, Department of Psychiatry, Tehran Institute of Psychiatry

Study Record Dates

• First Submitted: October 25, 2024
• First Posted: October 29, 2024
• Study Start: August 10, 2024
• Primary Completion: August 30, 2024
• Study Completion: September 30, 2024
• Last Updated: October 31, 2024

Record last verified: 2024-10

Locations

IR (1)