Major Depressive Disorder (MDD)
192
67
75
58
Key Insights
Highlights
Success Rate
91% trial completion (above average)
Published Results
15 trials with published results (8%)
Research Maturity
58 completed trials (30% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 40/100
3.1%
6 terminated out of 192 trials
90.6%
+4.1% vs benchmark
17%
32 trials in Phase 3/4
26%
15 of 58 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 58 completed trials
Clinical Trials (192)
Effectiveness of Clustered Versus Tapered Repetitive Transcranial Magnetic Stimulation (rTMS) as Maintenance Therapy Following Successful Acute rTMS Treatment in Patients With Depressive Syndrome
Probiotic IBNI617 for Moderate to Severe Depression: A Randomized Controlled Trial
Temporal Interference Transcranial Alternating Current Stimulation for Major Depressive Disorder and Generalized Anxiety Disorder
Investigating Functional Changes in the Frontotemporal Cortex of Patients With Major Depressive Disorder Following Electroconvulsive Therapy or Magnetic Seizure Therapy Using Functional Near-infrared Spectroscopy (fNIRS)
A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression
ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
Pattern Separation in Major Depressive Disorder
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
An Open-Label Extension Study to Evaluate the Safety and Tolerability of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 OLE Study)
Imaging- vs. Scalp-Targeted Accelerated TMS for Depression: The Number Needed to Scan Trial
Inhaled DMT for Major Depressive Disorder
Cannabidiol Oil for Treatment-Resistant Major Depression
Predictors of Relapse in Major Depressive Disorder (PERFORM-D)
6 Weeks Right-Amygdala TIS for Depression
Repeated Real-time Biofeedback With 7-Tesla MRI for Treatment of Depression
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
Efficacy of kTMP, a Novel Non-invasive Brain Stimulation Method, for the Treatment of Anhedonia
A Study of ONO-1110 in Patients With Major Depressive Disorder
Pregnenolone for Cannabis Use Disorder and Depression
A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression