Enhancing Communication on Relationship Preservation, Safer Conception and PrEP to Promote HIV Testing in Uganda

NCT06647797 | Completed

• 2 other identifiers: STUDY000024005R34MH132473
• Study Type: interventional
• Target: 7,666
• Locations: 1 country
• Sites: 2

Brief Summary

Our novel communication strategy aims to promote HIV testing in Uganda with reassuring messages about the ability to have stable relationships and healthy families with the increased availability of pre-exposure prophylaxis (PrEP). We will evaluate the feasibility and acceptability of this communication strategy among clients and partners within assisted partner notification and antenatal care programs in two hospitals and evaluate preliminary effects.

Conditions

HIV; Antenatal Care; Pre-Exposure Prophylaxis; Antiretroviral Therapy

Keywords

Antiretroviral medication

Outcome Measures

Primary Outcomes (2)

• Change in rate of partner HIV testing (antenatal care)

  7 month baseline period and 7 month intervention period

• Change in rate of partner HIV testing (assisted partner notification)

  7 month baseline period and 7 month intervention period

Secondary Outcomes (3)

• Change overall facility-level HIV testing

  7 month baseline period and 7 month intervention period

• Change in PrEP uptake among eligible HIV negative partners

  7 month baseline period and 7 month intervention period

• Change in ART uptake among eligible HIV positive partners

  7 month baseline period and 7 month intervention period

Study Arms (2)

Communication intervention "HOPE"

EXPERIMENTAL

* Patient-facing education materials * Provider counseling job aid and training

Behavioral: HOPE Clinical Communication Campaign

Usual care

NO INTERVENTION

Usual care

Interventions

HOPE Clinical Communication Campaign BEHAVIORAL

* Patient-facing educational materials * Provider counseling training and job aid

Communication intervention "HOPE"

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Client or partner of client receiving antenatal or assisted partner notification services at one of two study hospitals (Gombe Hospital or Mityana Hospital)

You may not qualify if:

• Individuals under the age of 18 years (for interviews and surveys only)

Sponsors & Collaborators

• Makerere University: collaborator
• Children's Mercy Hospital Kansas City: lead
• National Institute of Mental Health (NIMH): collaborator

Study Sites (2)

Gombe Hospital

Gombe, Uganda

Location

Mityana Hospital

Mityana, Uganda

Location

Study Officials

• Emily Hurley, PhD

  Children's Mercy Kansas City

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctoral Research Faculty

Model Details: Two hospital sites. One randomized to implement the communication intervention, the other continuing with usual care

Study Record Dates

• First Submitted: October 16, 2024
• First Posted: October 18, 2024
• Study Start: September 15, 2024
• Primary Completion: July 4, 2025
• Study Completion: October 1, 2025
• Last Updated: January 16, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will share

Locations

UG (2)