NCT06638372

Brief Summary

The purpose of this project is to investigate the effects of caffeine chewing gum on the cognitive functions and special operations capabilities of special forces.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
16

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 5, 2024

Completed
Same day until next milestone

Study Start

First participant enrolled

October 5, 2024

Completed
1 day until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 6, 2024

Completed
9 days until next milestone

First Posted

Study publicly available on registry

October 15, 2024

Completed
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2025

Completed
Last Updated

June 26, 2025

Status Verified

June 1, 2025

Enrollment Period

1 day

First QC Date

October 5, 2024

Last Update Submit

June 24, 2025

Conditions

CaffeinePlacebo

Keywords

exercise performance

Outcome Measures

Primary Outcomes (2)

  • Stroop task

    The color-word Stroop task were conducted using Psych/Lab for Windows. The reaction time (millisecond) were recorded.

    15 minutes after intervention

  • visual search test

    The visual search test were conducted using Psych/Lab for Windows. The reaction time (millisecond) were recorded.

    15 minutes after intervention

Secondary Outcomes (1)

  • anti-terrorist operations

    15 minutes after intervention

Study Arms (2)

caffeine gum

EXPERIMENTAL

Chewing caffeine gum for 10 minutes

Dietary Supplement: caffeine

placebo gum

PLACEBO COMPARATOR

Chewing placebo gum for 10 minutes

Dietary Supplement: caffeine

Interventions

caffeineDIETARY_SUPPLEMENT

The participants chewing either caffeine Gum (CAF trial, containing 3 mg/kg of caffeine) or Placebo Gum (PL) for 10 minutes. After rested for 15 minutes, the participants underwent tests.

caffeine gumplacebo gum

Eligibility Criteria

Age20 Years - 40 Years
Sexmale(Gender-based eligibility)
Gender Eligibility DetailsOnly male subjects
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Active Special Warfare Unit members who have passed the Grade A Special Forces Reserve Training
  • No cardiovascular and joint diseases
  • Adult male over 20 years old

You may not qualify if:

  • Non-active Special Warfare Unit members
  • Have cardiovascular and joint diseases
  • Under age

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Taiwan University of Sport

Taichung, North, 404, Taiwan

Location

MeSH Terms

Interventions

Caffeine

Intervention Hierarchy (Ancestors)

XanthinesAlkaloidsHeterocyclic CompoundsPurinonesPurinesHeterocyclic Compounds, 2-RingHeterocyclic Compounds, Fused-Ring

Study Officials

  • ChihHui Chiu, PhD

    Professor

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

October 5, 2024

First Posted

October 15, 2024

Study Start

October 5, 2024

Primary Completion

October 6, 2024

Study Completion

May 30, 2025

Last Updated

June 26, 2025

Record last verified: 2025-06

Data Sharing

IPD Sharing
Will not share

Locations

TW(1)