Caffeine & Bodybuilding Dehydration Ability

NCT06431035 | Completed

• 1 other identifier: 113-3
• Study Type: interventional
• Target: 14
• Locations: 1 country
• Sites: 1

Brief Summary

15-20 trained bodybuilding athletes were divided into caffeine gum trial (CAF) and placebo trial (PL) with a randomized, double-blind study design. The participants chewing either caffeine Gum (CAF trial, containing 5 mg/kg of caffeine) or placebo gum (PL) for 10 minutes. After rested for 15 minutes, Participants used the bicycle to adjust the pedal resistance and speed according to their own feelings until they were dehydrated to 2% of their original body weight.

Conditions

Caffeine; Placebo

Outcome Measures

Primary Outcomes (1)

• dehydration speed

  The participants start dehydration until dehydrated to 2% of their original body weight.

  15 minutes after intervention

Secondary Outcomes (1)

• energy expenditure

  15 minutes after intervention

Study Arms (2)

caffeine gum

EXPERIMENTAL

Chewing caffeine Gum (CAF trial, containing 5 mg/kg of caffeine) for 10 minutes before test.

Dietary Supplement: caffeine

placebo

PLACEBO COMPARATOR

Chewing placebo gum (without caffeine) for 10 minutes before test.

Dietary Supplement: caffeine

Interventions

caffeine DIETARY_SUPPLEMENT

The participants chewed either caffeine gum (5 mg/kg for 10 minutes per chew) or a placebo (10 minutes per chew, using regular gum).

Also known as: plocabo gum

caffeine gum; placebo

Eligibility Criteria

• Age: 20 Years - 40 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• having won the top 8 places in a national competition,
• having no cardiovascular or joint diseases
• being an adult male

You may not qualify if:

• no top 8 finishes at national level
• cardiovascular or joint disease, or any other condition that could be impaired by exercise
• female and underage participants
• previous caffeine allergy

Sponsors & Collaborators

• Chih-Hui Chiu: lead

Study Sites (1)

National Taiwan University of Sport

Taichung, 404, Taiwan

Location

Related Publications (1)

• Liu HS, Okada T, Mitsuya H, Hsieh MH, Hou CW, Chang CC, Chiu CH. Effects of caffeinated chewing gum-induced sympathetic activation and diuretic effect on the rapid rate of weight loss in bodybuilders: a double-blind crossover study. BMC Sports Sci Med Rehabil. 2025 Apr 26;17(1):98. doi: 10.1186/s13102-025-01144-z.

  PMID: 40287780 DERIVED

MeSH Terms

Interventions

Caffeine

Intervention Hierarchy (Ancestors)

Xanthines; Alkaloids; Heterocyclic Compounds; Purinones; Purines; Heterocyclic Compounds, 2-Ring; Heterocyclic Compounds, Fused-Ring

Study Officials

• ChihHui Chiu, PhD

  National Taiwan University of Sport

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Masking Details: Using placebo chewing gum
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Professor

Model Details: The participants were divided into caffeine gum trial (CAF) and placebo trial (PL) with a randomized, double-blind study design.

Study Record Dates

• First Submitted: April 8, 2024
• First Posted: May 28, 2024
• Study Start: April 8, 2024
• Primary Completion: June 30, 2024
• Study Completion: June 30, 2024
• Last Updated: July 24, 2024

Record last verified: 2024-07

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)