NCT06635655

Brief Summary

New generation of lower limb prosthesis provide improved functionalities. They are usually studied in the scope of biomechanics, sometimes PROMs like quality of life. Following users feedback, it is desirable to better understand why and how mental workload is impacted by new technologies or features. This clinical investigation will try to measure a difference between different prosthetic systems, in lab and in daily life.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
9

participants targeted

Target at below P25 for all trials

Timeline
8mo left

Started Feb 2025

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress65%
Feb 2025Dec 2026

First Submitted

Initial submission to the registry

October 4, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 10, 2024

Completed
4 months until next milestone

Study Start

First participant enrolled

February 21, 2025

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2026

Expected
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2026

Last Updated

July 9, 2025

Status Verified

July 1, 2025

Enrollment Period

1.6 years

First QC Date

October 4, 2024

Last Update Submit

July 8, 2025

Conditions

Keywords

microprocessor controlledlower limb prosthesismental workload

Outcome Measures

Primary Outcomes (1)

  • Goal Attainment Scale (GAS)

    Scale from -3 to +2. The higher the better. -3 being a deterioration, -2 being the baseline, 0 the objective, +2 the maximum

    From enrollment to the end of treatment at 8 weeks

Secondary Outcomes (5)

  • L-test and Dual-task L-test

    Initial visit, at 4 weeks, and at 8 weeks

  • Two-minute walk test (2MWT) and 2MWT in divided attention

    Initial visit, at 4 weeks, and at 8 weeks

  • Activity Balance Confidence Scale (ABC-scale)

    at 4 weeks, and at 8 weeks

  • Prosthesis Evaluation Questionnaire (PEQ-A)

    at 4 weeks, and at 8 weeks

  • Stumbles and falls

    at 4 weeks, and at 8 weeks

Eligibility Criteria

Age18 Years - 84 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Population usually living or receiving care around investigation centers

You may qualify if:

  • above-knee lower limb amputation
  • using an above-knee prosthesis with prosthetic knee and foot
  • eligible to use Synsys
  • able to design therapeutic objectives for the GAS
  • having a smartphone

You may not qualify if:

  • protected person
  • pregnant or breast-feeding lady
  • knee-to-ground height lower than 43cm
  • weighting more than 125kg
  • using their prosthesis for less than 2 weeks
  • not covered by health insurance
  • aged less than 18 or more than 84 years old
  • bilateral amputee or hip disarticulated

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Multiple sites

Multiple Locations, France

RECRUITING

MeSH Terms

Conditions

Wounds and Injuries

Study Officials

  • Laurine Calistri, MS

    Proteor Group

    STUDY DIRECTOR
  • Isabelle Loiret, DR

    UGECM Nord-Est, IRR, Centre Louis Pierquin

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
CASE CROSSOVER
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 4, 2024

First Posted

October 10, 2024

Study Start

February 21, 2025

Primary Completion (Estimated)

September 30, 2026

Study Completion (Estimated)

December 31, 2026

Last Updated

July 9, 2025

Record last verified: 2025-07

Locations