Whole Body Vibration Training Applied with Different Frequencies in Hypertensive Patients

NCT05768555 | Completed

• 1 other identifier: DokuzEU-HT-001
• Study Type: interventional
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

At least 36 volunteers with a diagnosis of hypertension in the Department of Cardiology of Dokuz Eylul University and who meet the criteria for follow-up and inclusion will participate in the study. The aim of this study is to compare the acute effects on atherosclerosis, heart rate variability, blood pressure, perceived exertion, energy expenditure, and muscle strength of using different frequencies in whole body vibration training (WBVT) in hypertensive patients. Individuals will perform; static squat, dynamic toe raise, static abduction and dynamic squat exercises in both hips on a vibrating platform. In each session, a different frequency (0,25 and 40 Hz) will be applied. 0 Hz, 25 Hz and 40 Hz sessions will be randomized to last 15 minutes. Demographic and clinical information of the participants will be questioned.Before and after the sessions; hemodynamic and pulmonary responses, vascular responses, heart rate variability and quadriceps femoris muscle strength will be measured. In addition, energy expenditure will be recorded during the sessions.

Conditions

Hypertension

Keywords

hypertension; whole body vibration

Outcome Measures

Primary Outcomes (3)

• Arterial stiffness

  Arterial stiffness will be measured with a noninvasive method with the help of the SphygmocorXCEL device, which can automatically measure with the cuff. The patient's age(years), gender(male), blood pressure(mmHg), height(cm), weight(kg), carotid-sternal notch distance between the artery, carotid-femoral artery as the distance between the entered data to the computer after increasing pressure over the brachial artery through a transducer (augmentation index) and again, carotid-femoral pulse wave velocity via the artery (pulse wave velocity) measurements will be made.

  Change from the baseline to the first minutes after the intervention

• Heart rate variability

  Heart rate variability will be assessed by heart rate variability (HRV), a non-invasive measurement. Sympathetic and parasympathetic autonomic function will be evaluated with HRV software. HRV provides time and frequency domain parameters associated with autonomic function.

  Change from the baseline to the first minutes after the intervention

• Blood pressure

  Systolic and diastolic blood pressure will be measured with a sphygmomanometer.

  Change from the baseline to the first minutes after the intervention

Secondary Outcomes (5)

• Muscle strength

  Change from the baseline to the first minutes after the intervention

• Energy expenditure

  During exercise intervention, average 15 minutes

• Heart rate

  Change from the baseline to the first minutes after the intervention

• Perceived effort

  Change from the baseline to the first minutes after the intervention

• Respiratory frequency

  Change from the baseline to the first minutes after the intervention

Study Arms (3)

Whole body vibration intervention at 40 Hz

ACTIVE COMPARATOR

40 Hz frequency WBVT

Other: Whole body vibration intervention at 40 Hz

Whole body vibration intervention at 25 Hz

ACTIVE COMPARATOR

25 Hz frequency WBVT

Other: Whole body vibration intervention at 25 Hz

Whole body vibration intervention at 0 Hz

ACTIVE COMPARATOR

0 Hz frequency WBVT

Other: Whole body vibration intervention at 0 Hz

Interventions

Whole body vibration intervention at 40 Hz OTHER

Whole body vibration intervention will be performed with the Power Plate Pro 5 device (Power Plate International, London, UK). Whole body vibration training will be performed at a frequency of 40 Hz. Individuals will perform; static squat, dynamic toe raise, static abduction and dynamic squat exercises in both hips on a vibrating platform. All exercises will consist of 45 seconds of vibration and 15 seconds of rest. Each exercise will be repeated three times. Total intervention time will be 15 minutes.

Whole body vibration intervention at 40 Hz

Whole body vibration intervention at 25 Hz OTHER

Whole body vibration intervention will be performed with the Power Plate Pro 5 device (Power Plate International, London, UK). Whole body vibration training will be performed at a frequency of 25 Hz. Individuals will perform; static squat, dynamic toe raise, static abduction and dynamic squat exercises in both hips on a vibrating platform. All exercises will consist of 45 seconds of vibration and 15 seconds of rest. Each exercise will be repeated three times. Total intervention time will be 15 minutes.

Whole body vibration intervention at 25 Hz

Whole body vibration intervention at 0 Hz OTHER

Whole body vibration intervention will be performed with the Power Plate Pro 5 device (Power Plate International, London, UK). Whole body vibration training will be performed at a frequency of 0 Hz. Individuals will perform; static squat, dynamic toe raise, static abduction and dynamic squat exercises in both hips on a vibrating platform. All exercises will consist of 45 seconds of vibration and 15 seconds of rest. Each exercise will be repeated three times. Total intervention time will be 15 minutes.

Whole body vibration intervention at 0 Hz

Eligibility Criteria

• Age: 40 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Being diagnosed with hypertension
• Being clinically stable
• Becoming a volunteer
• Walking independently
• Not taking medication or hormone therapy in the year before the study
• Lack of regular exercise habit (\<60 minutes/week of exercise)

You may not qualify if:

• Having a serious cardiovascular/pulmonary condition
• Having an operation in the last 6 months
• Presence of acute thrombosis
• Presence of arrhythmia
• Presence of unstable angina
• Recent decompensated heart failure
• Recent myocardial infarction
• Using an assistive device to walk
• Neurological disorders (such as stroke, Parkinson's)
• Being diagnosed with vertigo
• Being diagnosed with epilepsy
• Kidney failure and history of kidney stones
• Hip or knee implants
• Recent fractures or injuries (\<6 months).
• Using a prosthesis

Sponsors & Collaborators

• Dokuz Eylul University: lead

Study Sites (1)

Dokuz Eylül University

Izmir, Balçova, 35140, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Hypertension

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Study Officials

• Sema Savcı

  Dokuz Eylul University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Master of Science

Study Record Dates

• First Submitted: February 23, 2023
• First Posted: March 14, 2023
• Study Start: October 14, 2022
• Primary Completion: June 13, 2023
• Study Completion: June 21, 2023
• Last Updated: November 20, 2024

Record last verified: 2023-05

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)