Examining Different Modes of Exercise for Acute Reduction in Blood Pressure
Examining the Effects of Aerobic Exercise, Isometrics, and Stretching on Acute (Post-exercise) Blood Pressure Reduction
1 other identifier
interventional
10
1 country
1
Brief Summary
The purpose of the study is to compared different modes of exercise for eliciting post-exercise hypotension. The study will randomize 10 healthy participants to 30 minutes of either aerobic exercise, isometric exercise, stretching, or rest (control). Blood pressure and heart rate will be assessed before and for one hour post-exercise.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable hypertension
Started Jan 2024
Shorter than P25 for not_applicable hypertension
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 4, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 10, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
April 15, 2024
CompletedFirst Submitted
Initial submission to the registry
October 3, 2024
CompletedFirst Posted
Study publicly available on registry
October 8, 2024
CompletedOctober 8, 2024
October 1, 2024
3 months
October 3, 2024
October 4, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Change in systolic blood pressure (mmHg)
Baseline to 60 minutes after exercise
Change in diastolic blood pressure (mmHg)
Baseline to 60 minutes after exercise
Secondary Outcomes (2)
Change in heart rate (beats per minute)
Baseline to 60 minutes after exercise
Change in rate-pressure product (beats per mintues x systolic blood pressure mmHg)
Change from baseline to 60 minutes after exercise
Study Arms (4)
Aerobic exercise
EXPERIMENTAL30 minutes of moderate-intensity aerobic exercise on a cycle ergometer
Isometric exercise
EXPERIMENTAL30 minutes of isometric exercise (alternating hand-grip with wall-sitting)
Static stretching
EXPERIMENTAL30 minutes of static stretching of major muscle groups
Resting control
ACTIVE COMPARATOR30 minutes of seated rest
Interventions
Eligibility Criteria
You may qualify if:
- Able to safely perform exercise according to the Get Active Questionnaire
You may not qualify if:
- Taking blood pressure medications
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Saskatchewan
Saskatoon, Saskatchewan, S7N5B2, Canada
Related Publications (1)
Keller C, Chilibeck P. Stretching, isometrics, and aerobic exercise for decreasing blood pressure post-exercise: a randomized crossover study. Appl Physiol Nutr Metab. 2025 Jan 1;50:1-6. doi: 10.1139/apnm-2024-0439.
PMID: 39869856DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
October 3, 2024
First Posted
October 8, 2024
Study Start
January 4, 2024
Primary Completion
April 10, 2024
Study Completion
April 15, 2024
Last Updated
October 8, 2024
Record last verified: 2024-10
Data Sharing
- IPD Sharing
- Will not share