Study of the Prevalence of Osteo-metabolic Complications in Patients With Thyroid Cancer

NCT06627998 | Recruiting

• 1 other identifier: OsteoTIR
• Study Type: observational
• Target: 82
• Locations: 1 country
• Sites: 1

Brief Summary

This is a multicenter retrospective observational study aimed to evaluate the prevalence of osteo-metabolic complications in patients with thyroid cancer.

Conditions

Cancer of Thyroid; Vertebral Fracture; Osteoporosis

Outcome Measures

Primary Outcomes (1)

• To estimate the incidence and prevalence of osteoporosis and vertebral fractures in Patients With Thyroid Cancer

  To estimate the incidence and prevalence of osteoporosis and vertebral fractures detected through DXA scan and vertebral morphometry. The effects on bone complications of the patients' clinical and biochemical characteristics will be investigated.

  1 year

Interventions

Diagnostic (chest x-ray /DXA)and clinical data collected for clinical practice DIAGNOSTIC_TEST

Biochemical, clinical and radiological data performed for clinical practice will be retrospectively collected. Osteoporosis and vertebral fractures will be diagnosed through DXA scan and vertebral morphometry.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with thyroid cancers who have been evaluated at the outpatient clinics of the Endocrinology Unit of the IRCCS San Raffaele Hospital and the Nuclear Medicine Unit of the Spedali Civili di Brescia.

You may qualify if:

• age ≥ 18 years
• Histological diagnosis of Thyroid Carcinoma
• radiological data from chest x-ray in lateral projection in the preoperative evaluation on which the vertebral morphometry
• Signing of the informed consent

You may not qualify if:

• Subjects not falling within the previously described criteria are excluded

Sponsors & Collaborators

• IRCCS San Raffaele: lead
• Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia: collaborator

Study Sites (1)

Andrea Giustina

Milan, 20132, Italy

RECRUITING

MeSH Terms

Conditions

Thyroid Neoplasms; Spinal Fractures; Osteoporosis

Interventions

Diagnosis; Diagnostic Imaging

Condition Hierarchy (Ancestors)

Endocrine Gland Neoplasms; Neoplasms by Site; Neoplasms; Head and Neck Neoplasms; Endocrine System Diseases; Thyroid Diseases; Spinal Injuries; Back Injuries; Wounds and Injuries; Fractures, Bone; Bone Diseases, Metabolic; Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Diagnostic Techniques and Procedures

Central Study Contacts

Luigi Di Filippo, medical doctor

CONTACT

0226435062; difilippo.luigi@hsr.it

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Endocrinology

Study Record Dates

• First Submitted: October 3, 2024
• First Posted: October 4, 2024
• Study Start: April 12, 2023
• Primary Completion: December 1, 2024
• Study Completion: December 1, 2024
• Last Updated: October 4, 2024

Record last verified: 2024-10

Locations

IT (1)