Effect Of The Presence Of Dynapenia On Posture, Spine Muscle Elasticity, Strength And Endurance In Young Adults

NCT06621875 | Not Yet Recruiting

• 1 other identifier: ATU-FTR-AY-01
• Study Type: observational
• Target: 40
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of the present study was to determine the effect of dynapenia on posture, spinal muscle elasticity, strength and endurance in young adults.

Conditions

Dynapenia; Muscle Weakness; Sarcopenia

Keywords

Muscle strength; Sarcopenia; Posture; Muscle elasticity; Muscle endurance; Dynapenia; Hand Grip

Outcome Measures

Primary Outcomes (4)

• Bioelectrical Impedance Analysis

  Bioelectrical impedance analysis is a method used to evaluate body composition \[30\]. Impedance refers to the resistance of tissue to electric current and is inversely proportional to conductivity. For example, components with high specific resistance such as bone and fat tissue make it difficult for electric current to pass, while components with low resistance such as skeletal muscle and visceral organs can easily conduct electric current. This principle forms the basis of bioelectrical impedance analysis \[31,32\]. Values of \< 8.87 kg/m2 in men and \< 6.42 kg/m2 in women were considered low muscle mass \[9\]. The Tanita BC 401 device will be used in the current study. Participants will be informed before the BIA measurement and will be asked not to drink alcohol for up to 48 hours, not to eat or drink 4 hours before, not to consume tea, coffee and cola for 12 hours before, and not to exercise. In addition, women's measurements will be taken outside of the menstrual period \[33,34\].

  two months

• Assessment of Muscle Strength

  Grip strength, will be measured using the JAMAR hand dynamometer and standardized protocol \[37\]. The JAMAR hand dynamometer is a reliable and most widely used measurement tool for measuring static grip strength \[35,38\]. Measurements are based on the principle of compressing two parallel bars. The participant is given a position suitable for holding and grip strength and the evaluation is made \[38,41\]. The needle of the JAMAR Hand Dynamometer can measure up to 90 kg \[37,39,42\]. The person should sit on a seat without arm support, with the arm in adduction and neutral rotation, the elbow in 90-degree flexion and the forearm in a neutral position \[43,44\]. The average of three trials for each hand was used to determine general grip strength. Inadequacy in hand grip strength was determined as less than 20 kg for women and less than 30 kg for men \[45\].

  two months

• Assessment of Muscle Performance: 4-Meter Walk Test(4-MWT)

  4-Meter Walk Test(4-MWT): (4-MWT) is a walking speed test that evaluates functional limitations and physical performance. (4-MWT) is a widely used test due to its simplicity and high test-retest reliability \[46\]. Test walking speed is the most commonly used and practical method for evaluating muscle performance in the clinic. A normal value is approximately 3.57 seconds. Additionally, walking speeds of less than 0.8 m/s have been associated with a risk of falling \[46,49\].

  two months

• Assessment of Muscle Performance: Sit-to-Stand Test(SST)

  Sit-to-Stand Test(SST): The participant is asked to stand up and sit down completely from a chair for one minute with the arms crossed at chest height from a standard chair height of 45 cm. The number of times the person stands up and sits down completely constitutes the total score \[50\]. During the test, the participant is seated upright on a chair with their feet touching the floor. The person's arms are crossed in front of their chest. The test is started with the command and the number of times the person gets up completely within 30 seconds is recorded. Only a chair and a stopwatch are required for the test. In the evaluations made for young adults, while for men, results below 15 repetitions in the 30-second sit-to-stand test can be considered as poor performance, this limit is determined as 12 repetitions for women \[51\].

  two months

Secondary Outcomes (7)

• Assessment of Posture Angles

  two months

• Evaluation of Spinal Muscle Elasticity

  two months

• Evaluation of The Strength And Endurance of The Spine Stabilization Muscles

  two months

• Measurement of The Strength With The Posterior Pelvic Tilt Movement

  two months

• Transversus Abdominis Strength Measurement

  two months

Study Arms (2)

Dynapenia Group

Those with no decrease in muscle mass but decreased muscle strength and/or performance will be included in the 'dynapenia group'.

Control Group

Those with no decrease in muscle mass, muscle function and performance will be included in the 'control group'.

Eligibility Criteria

• Age: 18 Years - 25 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Participants between the ages of 18-25 who agreed to participate in the study

You may qualify if:

• Being between the ages of 18-25
• Filling out all the survey questions

You may not qualify if:

• Presence of chronic diseases that may affect the musculoskeletal system (diabetes, heart disease, neurological disorders)
• Use of medications that may affect muscle functions (corticosteroids, muscle relaxants)
• Presence of serious musculoskeletal injury within the last six months
• Presence of surgery and/or pain related to the musculoskeletal system

Sponsors & Collaborators

• Aynur Ayazzade: lead

Related Publications (22)

• Orsso CE, Tibaes JRB, Oliveira CLP, Rubin DA, Field CJ, Heymsfield SB, Prado CM, Haqq AM. Low muscle mass and strength in pediatrics patients: Why should we care? Clin Nutr. 2019 Oct;38(5):2002-2015. doi: 10.1016/j.clnu.2019.04.012. Epub 2019 Apr 18.

  PMID: 31031136 BACKGROUND

• Clark BC, Manini TM. Functional consequences of sarcopenia and dynapenia in the elderly. Curr Opin Clin Nutr Metab Care. 2010 May;13(3):271-6. doi: 10.1097/MCO.0b013e328337819e.

  PMID: 20154609 BACKGROUND

• Manini TM, Clark BC. Dynapenia and aging: an update. J Gerontol A Biol Sci Med Sci. 2012 Jan;67(1):28-40. doi: 10.1093/gerona/glr010. Epub 2011 Mar 28.

  PMID: 21444359 BACKGROUND

• Newman AB, Kupelian V, Visser M, Simonsick EM, Goodpaster BH, Kritchevsky SB, Tylavsky FA, Rubin SM, Harris TB. Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort. J Gerontol A Biol Sci Med Sci. 2006 Jan;61(1):72-7. doi: 10.1093/gerona/61.1.72.

  PMID: 16456196 BACKGROUND

• Xue QL, Beamer BA, Chaves PH, Guralnik JM, Fried LP. Heterogeneity in rate of decline in grip, hip, and knee strength and the risk of all-cause mortality: the Women's Health and Aging Study II. J Am Geriatr Soc. 2010 Nov;58(11):2076-84. doi: 10.1111/j.1532-5415.2010.03154.x.

  PMID: 21054287 BACKGROUND

• Clark BC, Manini TM. What is dynapenia? Nutrition. 2012 May;28(5):495-503. doi: 10.1016/j.nut.2011.12.002.

  PMID: 22469110 BACKGROUND

• Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, Martin FC, Michel JP, Rolland Y, Schneider SM, Topinkova E, Vandewoude M, Zamboni M; European Working Group on Sarcopenia in Older People. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010 Jul;39(4):412-23. doi: 10.1093/ageing/afq034. Epub 2010 Apr 13.

  PMID: 20392703 BACKGROUND

• Andreo-Lopez MC, Zarco-Martin MT, Contreras-Bolivar V, Fernandez-Soto ML. Prevalence of Sarcopenia and Dynapenia and Related Clinical Outcomes in Patients with Type 1 Diabetes Mellitus. Nutrients. 2023 Nov 24;15(23):4914. doi: 10.3390/nu15234914.

  PMID: 38068772 BACKGROUND

• Ammar A, Brach M, Trabelsi K, Chtourou H, Boukhris O, Masmoudi L, Bouaziz B, Bentlage E, How D, Ahmed M, Muller P, Muller N, Aloui A, Hammouda O, Paineiras-Domingos LL, Braakman-Jansen A, Wrede C, Bastoni S, Pernambuco CS, Mataruna L, Taheri M, Irandoust K, Khacharem A, Bragazzi NL, Chamari K, Glenn JM, Bott NT, Gargouri F, Chaari L, Batatia H, Ali GM, Abdelkarim O, Jarraya M, Abed KE, Souissi N, Van Gemert-Pijnen L, Riemann BL, Riemann L, Moalla W, Gomez-Raja J, Epstein M, Sanderman R, Schulz SV, Jerg A, Al-Horani R, Mansi T, Jmail M, Barbosa F, Ferreira-Santos F, Simunic B, Pisot R, Gaggioli A, Bailey SJ, Steinacker JM, Driss T, Hoekelmann A. Effects of COVID-19 Home Confinement on Eating Behaviour and Physical Activity: Results of the ECLB-COVID19 International Online Survey. Nutrients. 2020 May 28;12(6):1583. doi: 10.3390/nu12061583.

  PMID: 32481594 BACKGROUND

• Faulkner JA, Larkin LM, Claflin DR, Brooks SV. Age-related changes in the structure and function of skeletal muscles. Clin Exp Pharmacol Physiol. 2007 Nov;34(11):1091-6. doi: 10.1111/j.1440-1681.2007.04752.x.

  PMID: 17880359 BACKGROUND

• Wahlstrom J. Ergonomics, musculoskeletal disorders and computer work. Occup Med (Lond). 2005 May;55(3):168-76. doi: 10.1093/occmed/kqi083.

  PMID: 15857896 BACKGROUND

• Callaghan JP, McGill SM. Low back joint loading and kinematics during standing and unsupported sitting. Ergonomics. 2001 Feb 20;44(3):280-94. doi: 10.1080/00140130118276.

  PMID: 11219760 BACKGROUND

• Herzog W. Mechanisms of enhanced force production in lengthening (eccentric) muscle contractions. J Appl Physiol (1985). 2014 Jun 1;116(11):1407-17. doi: 10.1152/japplphysiol.00069.2013. Epub 2013 Feb 21.

  PMID: 23429875 BACKGROUND

• Rassier DE, MacIntosh BR, Herzog W. Length dependence of active force production in skeletal muscle. J Appl Physiol (1985). 1999 May;86(5):1445-57. doi: 10.1152/jappl.1999.86.5.1445.

  PMID: 10233103 BACKGROUND

• Flatters I, Mushtaq F, Hill LJ, Holt RJ, Wilkie RM, Mon-Williams M. The relationship between a child's postural stability and manual dexterity. Exp Brain Res. 2014 Sep;232(9):2907-17. doi: 10.1007/s00221-014-3947-4. Epub 2014 May 14.

  PMID: 24825824 BACKGROUND

• Aird L, Samuel D, Stokes M. Quadriceps muscle tone, elasticity and stiffness in older males: reliability and symmetry using the MyotonPRO. Arch Gerontol Geriatr. 2012 Sep-Oct;55(2):e31-9. doi: 10.1016/j.archger.2012.03.005. Epub 2012 Apr 13.

  PMID: 22503549 BACKGROUND

• Chuang LL, Wu CY, Lin KC. Reliability, validity, and responsiveness of myotonometric measurement of muscle tone, elasticity, and stiffness in patients with stroke. Arch Phys Med Rehabil. 2012 Mar;93(3):532-40. doi: 10.1016/j.apmr.2011.09.014. Epub 2012 Jan 4.

  PMID: 22222143 BACKGROUND

• Conable K, Corneal J, Hambrick T, Marquina N, Zhang J. Investigation of Methods and Styles of Manual Muscle Testing by AK Practitioners. J Chiropr Med. 2005 Winter;4(1):1-10. doi: 10.1016/S0899-3467(07)60106-2.

  PMID: 19674640 BACKGROUND

• von Garnier K, Koveker K, Rackwitz B, Kober U, Wilke S, Ewert T, Stucki G. Reliability of a test measuring transversus abdominis muscle recruitment with a pressure biofeedback unit. Physiotherapy. 2009 Mar;95(1):8-14. doi: 10.1016/j.physio.2008.10.003. Epub 2009 Jan 22.

  PMID: 19627680 BACKGROUND

• Bohannon R, Gajdosik R, LeVeau BF. Contribution of pelvic and lower limb motion to increases in the angle of passive straight leg raising. Phys Ther. 1985 Apr;65(4):474-6. doi: 10.1093/ptj/65.4.474.

  PMID: 3983239 BACKGROUND

• Harris KD, Heer DM, Roy TC, Santos DM, Whitman JM, Wainner RS. Reliability of a measurement of neck flexor muscle endurance. Phys Ther. 2005 Dec;85(12):1349-55.

  PMID: 16305273 BACKGROUND

• McGill SM, Childs A, Liebenson C. Endurance times for low back stabilization exercises: clinical targets for testing and training from a normal database. Arch Phys Med Rehabil. 1999 Aug;80(8):941-4. doi: 10.1016/s0003-9993(99)90087-4.

  PMID: 10453772 BACKGROUND

MeSH Terms

Conditions

Muscle Weakness; Sarcopenia

Condition Hierarchy (Ancestors)

Muscular Diseases; Musculoskeletal Diseases; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Signs and Symptoms; Muscular Atrophy; Atrophy; Pathological Conditions, Anatomical

Central Study Contacts

Aynur Ayazzade

CONTACT

+905010856913; aynurayazzadeh@gmail.com

Yusuf Can Altindaş

CONTACT

+ 905438541716; yusufcanaltindas@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Graduate Student

Study Record Dates

• First Submitted: September 28, 2024
• First Posted: October 1, 2024
• Study Start: November 1, 2024
• Primary Completion: March 1, 2025
• Study Completion: October 1, 2025
• Last Updated: October 16, 2024

Record last verified: 2024-10