NCT02530723

Brief Summary

Extending quality of life and attenuating functional decline is paramount in older adults. This study investigates the effects of low-intensity power-training in older women and its effects on functional outcomes.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2015

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 17, 2015

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 21, 2015

Completed
11 days until next milestone

Study Start

First participant enrolled

September 1, 2015

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 16, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 16, 2018

Completed
Last Updated

November 9, 2020

Status Verified

November 1, 2020

Enrollment Period

2.9 years

First QC Date

August 17, 2015

Last Update Submit

November 5, 2020

Conditions

Keywords

power traininghigh-speed traininghigh-velocity trainingfunctionolder adultsolder women

Outcome Measures

Primary Outcomes (1)

  • Change in Stair-climb power

    The time needed to ascend a flight of stairs, converted to power (using body-weight and stair height)

    baseline, 6 weeks, 12 weeks

Secondary Outcomes (3)

  • Change in 400-meter walk test

    baseline, 6 weeks, 12 weeks

  • Change in Short Physical Performance Battery

    baseline, 6 weeks, 12 weeks

  • Change in 30-second chair stand test

    baseline, 6 weeks, 12 weeks

Study Arms (4)

Once a week

EXPERIMENTAL

Group 1 will be invited to perform resistance training exercise 1 day/week. After a 2-week familiarization phase, participants will engage in power training (40% of 1-repetition maximum) for 12 weeks. Instructions include telling participants to lift the weight concentrically 'as fast as possible', with a lowering phase (eccentric) of 2-3 seconds. Participants will perform 3 x 12-14 repetitions per exercise per session. Primarily lower body equipment will be used, including leg press, knee extension/flexion, hip extension/flexion, and calf-raises.

Other: power training

Twice a week

EXPERIMENTAL

Group 2 will be invited to perform resistance training exercise 2 days/week. After a 2-week familiarization phase, participants will engage in power training (40% of 1-repetition maximum) for 12 weeks. Instructions include telling participants to lift the weight concentrically 'as fast as possible', with a lowering phase (eccentric) of 2-3 seconds. Participants will perform 3 x 12-14 repetitions per exercise per session. Primarily lower body equipment will be used, including leg press, knee extension/flexion, hip extension/flexion, and calf-raises.

Other: power training

Thrice a week

EXPERIMENTAL

Group 3 will be invited to perform resistance training exercise 3 days/week. After a 2-week familiarization phase, participants will engage in power training (40% of 1-repetition maximum) for 12 weeks. Instructions include telling participants to lift the weight concentrically 'as fast as possible', with a lowering phase (eccentric) of 2-3 seconds. Participants will perform 3 x 12-14 repetitions per exercise per session. Primarily lower body equipment will be used, including leg press, knee extension/flexion, hip extension/flexion, and calf-raises.

Other: power training

wait-control

NO INTERVENTION

Participants in this group will serve as controls prior to participating in power training in 1 of the above treatment groups. The control period will last as long as the exercise period, or 3 months. Controls will participate in the same testing time points as the exercisers (baseline, midpoint, and post-intervention).

Interventions

Resistance training machines with CAM devices will be used for training.

Also known as: resistance training, high-speed training, high-velocity training
Once a weekThrice a weekTwice a week

Eligibility Criteria

Age65 Years+
Sexfemale
Healthy VolunteersYes
Age GroupsOlder Adult (65+)

You may qualify if:

  • females, 65 years of age
  • agree to the study protocol
  • give informed-consent to the proposed research study

You may not qualify if:

  • existing acute illness/disease (last six months)
  • diagnosed with myopathies
  • currently prescribed cardiovascular medications or drugs that may affect muscle mass and/or their response to exercise (thyroid medications, sedatives, beta blockers, some statins)
  • are diabetic
  • have uncontrolled hypertension
  • have been advised against participating in exercise by their doctor

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Athletic Centre; 55 Harbord Street

Toronto, Ontario, M5S 2W6, Canada

Location

Related Publications (13)

  • Fiatarone MA, O'Neill EF, Ryan ND, Clements KM, Solares GR, Nelson ME, Roberts SB, Kehayias JJ, Lipsitz LA, Evans WJ. Exercise training and nutritional supplementation for physical frailty in very elderly people. N Engl J Med. 1994 Jun 23;330(25):1769-75. doi: 10.1056/NEJM199406233302501.

    PMID: 8190152BACKGROUND
  • Hartman MJ, Fields DA, Byrne NM, Hunter GR. Resistance training improves metabolic economy during functional tasks in older adults. J Strength Cond Res. 2007 Feb;21(1):91-5. doi: 10.1519/00124278-200702000-00017.

    PMID: 17313273BACKGROUND
  • Hanson ED, Srivatsan SR, Agrawal S, Menon KS, Delmonico MJ, Wang MQ, Hurley BF. Effects of strength training on physical function: influence of power, strength, and body composition. J Strength Cond Res. 2009 Dec;23(9):2627-37. doi: 10.1519/JSC.0b013e3181b2297b.

    PMID: 19910811BACKGROUND
  • Pojednic RM, Clark DJ, Patten C, Reid K, Phillips EM, Fielding RA. The specific contributions of force and velocity to muscle power in older adults. Exp Gerontol. 2012 Aug;47(8):608-13. doi: 10.1016/j.exger.2012.05.010. Epub 2012 May 22.

    PMID: 22626972BACKGROUND
  • Sayers SP, Guralnik JM, Thombs LA, Fielding RA. Effect of leg muscle contraction velocity on functional performance in older men and women. J Am Geriatr Soc. 2005 Mar;53(3):467-71. doi: 10.1111/j.1532-5415.2005.53166.x.

    PMID: 15743291BACKGROUND
  • Miszko TA, Cress ME, Slade JM, Covey CJ, Agrawal SK, Doerr CE. Effect of strength and power training on physical function in community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2003 Feb;58(2):171-5. doi: 10.1093/gerona/58.2.m171.

    PMID: 12586856BACKGROUND
  • Sayers SP, Gibson K. Effects of high-speed power training on muscle performance and braking speed in older adults. J Aging Res. 2012;2012:426278. doi: 10.1155/2012/426278. Epub 2012 Feb 28.

    PMID: 22500229BACKGROUND
  • Henwood TR, Riek S, Taaffe DR. Strength versus muscle power-specific resistance training in community-dwelling older adults. J Gerontol A Biol Sci Med Sci. 2008 Jan;63(1):83-91. doi: 10.1093/gerona/63.1.83.

    PMID: 18245765BACKGROUND
  • Drey M, Zech A, Freiberger E, Bertsch T, Uter W, Sieber CC, Pfeifer K, Bauer JM. Effects of strength training versus power training on physical performance in prefrail community-dwelling older adults. Gerontology. 2012;58(3):197-204. doi: 10.1159/000332207. Epub 2011 Nov 3.

    PMID: 22056537BACKGROUND
  • Earles DR, Judge JO, Gunnarsson OT. Velocity training induces power-specific adaptations in highly functioning older adults. Arch Phys Med Rehabil. 2001 Jul;82(7):872-8. doi: 10.1053/apmr.2001.23838.

    PMID: 11441371BACKGROUND
  • Bamman MM, Hill VJ, Adams GR, Haddad F, Wetzstein CJ, Gower BA, Ahmed A, Hunter GR. Gender differences in resistance-training-induced myofiber hypertrophy among older adults. J Gerontol A Biol Sci Med Sci. 2003 Feb;58(2):108-16. doi: 10.1093/gerona/58.2.b108.

    PMID: 12586847BACKGROUND
  • Hunter GR, Wetzstein CJ, McLafferty CL Jr, Zuckerman PA, Landers KA, Bamman MM. High-resistance versus variable-resistance training in older adults. Med Sci Sports Exerc. 2001 Oct;33(10):1759-64. doi: 10.1097/00005768-200110000-00022.

    PMID: 11581563BACKGROUND
  • Katsoulis K, Amara CE. The Effects of Power Training Frequency on Muscle Power and Functional Performance in Older Women: A Randomized Controlled Trial. J Strength Cond Res. 2023 Nov 1;37(11):2289-2297. doi: 10.1519/JSC.0000000000004527. Epub 2023 Jun 19.

MeSH Terms

Conditions

SarcopeniaMuscle Weakness

Interventions

Resistance Training

Condition Hierarchy (Ancestors)

Muscular AtrophyNeuromuscular ManifestationsNeurologic ManifestationsNervous System DiseasesAtrophyPathological Conditions, AnatomicalPathological Conditions, Signs and SymptomsSigns and SymptomsMuscular DiseasesMusculoskeletal DiseasesPathologic Processes

Intervention Hierarchy (Ancestors)

Exercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesPhysical Conditioning, HumanExerciseMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Catherine E Amara, Ph.D

    University of Toronto; Faculty of Kinesiology and Physical Education

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Masking Details
Functional testers are masked to what group the participants are in (control, Exercise Group I, II, or III). All testers are masked during baseline testing.
Purpose
TREATMENT
Intervention Model
FACTORIAL
Model Details: With 3 groups and a wait-control group, our general design will include 4 (group) x 2 (baseline and post-study) and 4 (group) x 3 (baseline, midpoint, and post-study) analyses. We may also conduct one-way ANOVA analyses as problems with normality in the data are apparent.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Konstantina Katsoulis

Study Record Dates

First Submitted

August 17, 2015

First Posted

August 21, 2015

Study Start

September 1, 2015

Primary Completion

July 16, 2018

Study Completion

July 16, 2018

Last Updated

November 9, 2020

Record last verified: 2020-11

Locations