Anomia Treatment Predictors

NCT06619756 | Completed

• 1 other identifier: STUDY00008623
• Study Type: interventional
• Target: 2
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this clinical trial is to identify predictors of response to phonological-focused anomia treatment in people with aphasia. The main question it aims to answer is who responds to which type of anomia treatment. Researchers will compare Phonomotor Treatment and Phonological Components Analysis to see which treatment is more beneficial, and for whom. Participants will engage in both treatments over several months.

Conditions

Anomia (Word-Finding Impairment); Aphasia

Keywords

anomia treatment; aphasia treatment

Outcome Measures

Primary Outcomes (1)

• Naming of Trained Words

  Picture naming of trained words

  Pre-treatment and Immediately post-treatment

Secondary Outcomes (3)

• Naming of Untrained Words

  Pre-treatment and Immediately post-treatment

• Standardized Assessment of Phonology in Aphasia (SAPA)

  Pre-treatment and Immediately post-treatment

• Philadelphia Naming Test

  Pre-treatment and Immediately post-treatment

Study Arms (2)

PMT

EXPERIMENTAL

Phonomotor Treatment (PMT) will be administered. This treatment improves anomia by training the sound sequences of words. This is a multimodal treatment approach that includes listening, producing, visualizing, and describing sounds and sound sequences. The participant practices the sound sequence tasks with the clinician.

Behavioral: Phonomotor Treatment (PMT)

PCA

EXPERIMENTAL

Phonological Components Analysis (PCA) will be administered. This treatment improves anomia by identifying phonological features of words. A picture is presented. The participant provides features of the picture name: the first sound of the word, the final sound of the word, the number of syllables of the word, another word that starts with the same sound, and another words that rhymes with the word. The participant attempts to produce the word independently and by repeating after the clinician.

Behavioral: Phonological Components Analysis (PCA)

Interventions

Phonomotor Treatment (PMT) BEHAVIORAL

Anomia treatment focuses on improving word-finding abilities. This intervention targets the phonology of words to improve word-finding.

PMT

Phonological Components Analysis (PCA) BEHAVIORAL

Anomia treatment focuses on improving word-finding abilities. This intervention targets the phonology of words to improve word-finding.

PCA

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Chronic aphasia (6+ months)
• Anomia
• Sufficient auditory comprehension to follow task instructions
• Phonologic impairment

You may not qualify if:

• Progressive neurological illness or disease, including dementia
• Chronic medical illness that interferes with adherence to testing schedule
• Severe, uncorrected vision or hearing impairment that interferes with task completion
• Moderate-severe apraxia of speech or dysarthria that interferes with task completion

Sponsors & Collaborators

• State University of New York at Buffalo: lead

Study Sites (1)

UB Audiology and Speech-Language Pathology Clinic

Buffalo, New York, 14214, United States

Location

MeSH Terms

Conditions

Anomia; Aphasia

Condition Hierarchy (Ancestors)

Language Disorders; Communication Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Speech Disorders

Study Officials

• Nichol Castro, PhD

  SUNY at Buffalo

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: September 27, 2024
• First Posted: October 1, 2024
• Study Start: September 18, 2024
• Primary Completion: October 1, 2025
• Study Completion: October 1, 2025
• Last Updated: November 12, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)