Motivational Interviews Post Hospitalisation on Maintaining AbstiNence for 1 Year après le Sevrage en Alcool

NCT06618755 | Recruiting

• 1 other identifier: RECHMPL22_0564
• Study Type: interventional
• Target: 104
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this clinical study is to evaluate the efficacy of reinforced inpatient aftercare versus usual care on the percentage of days of abstinence during the first year following withdrawal in adults with alcohol use disorders undergoing inpatient withdrawal. The hypothesis is that reinforced post-withdrawal follow-up, of the motivational interview type, during the first 4 months following hospitalisation, in addition to the usual care, would allow :

• Increase the percentage of days of abstinence in the year following withdrawal.
• Reduce the rate of relapse in the year following withdrawal.
• An increase in the cumulative and maximum duration of abstinence, an increase in motivation to maintain the change initiated and a reduction in the use of other substances in the year following withdrawal.
• A reduction in the impact of risk factors involved in the relapse process in the year following withdrawal. All participants will have assessments to monitor their abstinence and consumption. In addition to their assessments, the experimental group will have motivational talks once every 15 days.

Conditions

Alcohol Use Disorder; Addiction; Alcohol Withdrawal; Motivational Interviews; Relapse

Outcome Measures

Primary Outcomes (1)

• Percentage of days of abstinence over the 12 months following hospitalization for alcohol

  The measures used for our main criterion will be declarative and collected on paper and by telephone every month in terms of the number of drinks per day. To facilitate data collection, the Timeline Follow Back method \[30\], developed by Sobell and also validated by telephone, will be used. This tool enables estimates of daily consumption of standard glasses to be collected retrospectively (for up to 12 months). The advantage of this method is that it reduces recall bias, since the participant can fill in a calendar from day to day and the data are collected every month.

  From inclusion,once a month for 1 year

Secondary Outcomes (8)

• Relapse rates at 5 and 12 months

  From inclusion,once a month for 1 year

• Cumulative duration (in days) and maximum duration of abstinence over 5 and 12 months

  Assessed 5 months after inclusion and 12 months after inclusion

• Motivation to maintain abstinence

  Assessed 0 month, 5 months and 12 months after inclusion

• Craving felt

  Assessed 0 month, 5 months and 12 months after inclusion

• Effectiveness of coping strategies

  Assessed 0 month, 5 months and 12 months after inclusion

Study Arms (2)

Experimental group : PSH (usual care) with motivational interviewing

EXPERIMENTAL

People randomised to the experimental group will have scheduled appointments to collect study data (monthly assessment). They will take part in an initial motivational interview to lay the foundations for the work that will be carried out throughout the follow-up period. Then, for 4 and a half months, a motivational interview will be scheduled every 14 days.

Other: Experimental group : PSH (usual care) with motivational interviewing

Control group : PSH (usual care)

NO INTERVENTION

People randomised to the control group will have scheduled appointments for study-related data collection (monthly assessment), in addition to their routine care.

Interventions

Experimental group : PSH (usual care) with motivational interviewing OTHER

The experimental group will begin follow-up after the 1st inclusion visit, during hospitalisation for withdrawal. The first motivational interview will take place 1 to 4 days before discharge from full hospitalisation. The following 10 motivational interviews will be held 2 weeks apart and will follow a framework based on the following objectives: to create a relationship of trust and an effective and lasting therapeutic alliance from the first interview; to create personalised objectives for the user, in line with their addictive pathology; to support the user as they modify, 'fail' and 'succeed' in achieving these objectives; to encourage the emergence and maintenance of the user's desire to change.

Experimental group : PSH (usual care) with motivational interviewing

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• With alcohol use disorders defined by at least 2 DSM-V criteria for at least 12 months).
• Being treated for withdrawal in hospital.
• With a goal of complete abstinence.
• With a means of communication (telephone).

You may not qualify if:

• Lack of understanding (written and spoken) of the French language.
• Breach of HC withdrawal contract, following failure to comply with the rules of the addictology service and somatic complications of addiction.
• Eviction from the department, discharge against medical advice during hospitalisation for withdrawal.
• Proven cognitive problems compromising understanding of the implications of the study and the proposed follow-up. proposed follow-up.
• Serious decompensated somatic pathology.
• Non-membership or non-beneficiaries of a national health insurance scheme.
• Person protected by law, under guardianship or curatorship.
• Not having signed free and informed consent to participate in the research.
• Simultaneous participation in another clinical trial.

Sponsors & Collaborators

• University Hospital, Montpellier: lead

Study Sites (1)

Thomas RISDORFER DE ISSDENTZI

Montpellier, 3400, France

RECRUITING

MeSH Terms

Conditions

Alcoholism; Behavior, Addictive; Recurrence

Condition Hierarchy (Ancestors)

Alcohol-Related Disorders; Substance-Related Disorders; Chemically-Induced Disorders; Mental Disorders; Compulsive Behavior; Impulsive Behavior; Behavior; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Thomas RISDORFER DE ISSDENTZI

CONTACT

04 67 33 70 20; t-risdorferdeissdentzi@chu-montpellier.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 24, 2024
• First Posted: October 1, 2024
• Study Start: December 18, 2024
• Primary Completion (Estimated): January 13, 2028
• Study Completion (Estimated): January 13, 2028
• Last Updated: June 18, 2026

Record last verified: 2026-06

Locations

FR (1)