Key Insights

Highlights

Success Rate

92% trial completion (above average)

Published Results

137 trials with published results (22%)

Research Maturity

283 completed trials (46% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

3.9%

24 terminated out of 617 trials

Success Rate

92.2%

+5.7% vs benchmark

Late-Stage Pipeline

6%

35 trials in Phase 3/4

Results Transparency

48%

137 of 283 completed with results

Key Signals

137 with results92% success24 terminated

Data Visualizations

Phase Distribution

560Total
Not Applicable (327)
Early P 1 (15)
P 1 (52)
P 2 (131)
P 3 (14)
P 4 (21)

Trial Status

Completed283
Recruiting142
Not Yet Recruiting45
Unknown45
Active Not Recruiting42
Terminated24

Trial Success Rate

92.2%

Benchmark: 86.5%

Based on 283 completed trials

Clinical Trials (617)

Showing 20 of 20 trials
NCT06860607Phase 1RecruitingPrimary

Environment and Alcohol: A Pilot Study

NCT06004830Phase 2Active Not RecruitingPrimary

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 1

NCT06006143Phase 2Active Not RecruitingPrimary

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2

NCT07191561Not Yet RecruitingPrimary

Hepatic Lipid Metabolism-Alcohol Use Disorder

NCT05807139Phase 1RecruitingPrimary

Spironolactone in Alcohol Use Disorder (SAUD)

NCT07218354Phase 3Not Yet RecruitingPrimary

Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial to Evaluate the Efficacy and Safety of a GLP-1 Receptor Agonist Semaglutide in U.S. Veterans With Alcohol Use Disorder

NCT04946851Enrolling By Invitation

Addictions Neuroclinical Assessment (ANA)

NCT06305624Not ApplicableRecruitingPrimary

Implementation of Mobile-based Programs for Alcohol Cessation in Treatment of Alcohol-associated Liver Disease

NCT06304467Not ApplicableActive Not RecruitingPrimary

CM for Patients With ALD After Liver Transplant

NCT07525258Not ApplicableNot Yet RecruitingPrimary

Implementation Facilitation Pilot for Alcohol Use Disorder (AUD) in Alcohol-associated Liver Disease (ALD)

NCT07027839Phase 1RecruitingPrimary

Acute Effects of Alcohol on PET Imaging of Phosphodiesterase-4B (PDE4B)

NCT05594238Not ApplicableActive Not RecruitingPrimary

Leveraging Virtual Care Strategies to Improve Access and Treatment for Individuals With Alcohol Use Disorders

NCT04523922Phase 2Active Not Recruiting

Oxytocin to Enhance Integrated Treatment for AUD and PTSD

NCT07520292Phase 1RecruitingPrimary

Study of NTX-2001 on Alcohol Consumption in Alcohol Use Disorder

NCT07325266Phase 2RecruitingPrimary

Human Laboratory Study of Apremilast for Alcohol Use Disorder

NCT04043442Phase 2Enrolling By InvitationPrimary

rTMS Target Identification for Functional Disability in AUD+mTBI

NCT06015893Phase 2Recruiting

Semaglutide Therapy for Alcohol Reduction (STAR)

NCT07281261Not ApplicableRecruitingPrimary

tAN for Substance Use Disorder

NCT06552741Recruiting

Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP

NCT02231840RecruitingPrimary

NIAAA Natural History Protocol

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Research Network

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