Peer Support in Alcohol Dependence
PEERSIAD
Contribution of Addiction Peer Support on Adherence to Care and Clinical Outcomes in Alcohol Dependence: a Prospective Controlled Trial With Medico-economic Component
1 other identifier
interventional
626
1 country
5
Brief Summary
Alcohol use disorder (AUD) affects between 4% and 6% of French adults, and requires appropriate medical treatment. However, 20-40% of patients with AUD are lost to follow-up at an early stage. Consequently, it is important for addiction departments to implement and evaluate innovative tools and interventions, including the involvement of peer support, to help patients remain in care, and to assess whether peer support has a positive impact on their clinical outcome. Addiction peer support specialists (APSSs) are individuals who have personally experienced addiction, and who have decided to use their experience to assist other people going through a similar situation, after completing a specific official graduation. Compared to other caregivers, APSSs may induce in patients a sense of identification which could improve the patient motivation to engage and remain in care. This is the main hypothesis and the main scientific objective of the PEERSIAD study, which will aim to confirm that accompanying patients with AUD using APSSs after alcohol detoxification, reduces the rate of lost-to-follow-up and improves the overall clinical outcome.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Oct 2024
Longer than P75 for not_applicable
5 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 2, 2024
CompletedFirst Posted
Study publicly available on registry
April 24, 2024
CompletedStudy Start
First participant enrolled
October 1, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2028
ExpectedStudy Completion
Last participant's last visit for all outcomes
April 1, 2028
June 11, 2024
April 1, 2024
3.5 years
April 2, 2024
June 10, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Unplanned cessation of care at 6 months
The unplanned cessation of care at 6 months, excluding consultations with an APSS, with no further contact in the following month, is defined as having had a last planned consultation that was not fulfilled between M0 and M6
At 6 months after inclusion
Secondary Outcomes (23)
Number of unfulfilled consultations
6 months after inclusion
Euroqol-5D-5L questionnaire score
At inclusion, 3 and 6 months after inclusion
Difference in costs (in euros)
At 1, 2 and 3 years after the beginning of implementation on French territory
Number of AUD criteria according to Diagnostic and Statistical Manual of Mental Disorders (DSM-5)
At inclusion, 3 and 6 months after inclusion
Alcohol Use Disorders Identification Test-Consumption (AUDIT-C) score
At inclusion, 3 and 6 months after inclusion
- +18 more secondary outcomes
Study Arms (2)
Peer support Group
EXPERIMENTAL313 patients will be recruited over 3 years in the peer support group. Patients will be accompanied by an addiction peer support specialist, as part of an "add-on" follow-up compared with conventional follow-up (same management as in the control group).
Control Group
ACTIVE COMPARATOR313 patients will be recruited over 3 years in the control group. Patients will receive "as usual" outpatient abstinence-maintenance follow-up, with consultations of all kinds (medical, psychological, nursing, group, etc.)
Interventions
Quality life questionnaire AQoLS will be completed by patients of both arms at inclusion, three and six months after inclusion
Quality life questionnaire Euroqol EQ-5D-5L will be completed by patients of both arms at inclusion, three and six months after inclusion
For patients included in the Peer support group, eight mandatory consultations with a peer support specialist will be performed between the inclusion visit and during the three following months. Patients can request additional consultations with the peer support specialist during the 6 first months of follow-up
Eligibility Criteria
You may qualify if:
- Aged ≥ 18
- Socially insured
- Meeting DSM-5 criteria for alcohol use disorder (AUD)
- Abstinent from alcohol and involved in supervised alcohol withdrawal for at least 5 days and no more than 21 days (outpatient or inpatient)
- Starting a post-detoxification outpatient program
You may not qualify if:
- Other severe substance use disorder, i.e. DSM-5 criteria ≥ 6 (excluding tobacco)
- Patient under protective measure (safeguard measure, guardianship) or deprived of liberty or in ordered care and hospitalization measures without consent.
- Inability to communicate and express oneself orally in French, compromising the possibility of exchanges between the Peer support and the patient.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (5)
CH Le Vinatier
Bron, 69500, France
Hôpital Beaujon
Clichy, 92110, France
GH Nord, Hospices Civils de Lyon
Lyon, 69004, France
CHS St Anne
Paris, 75014, France
Bichat Hospital
Paris, 75018, France
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Benjamin ROLLAND
Hopsices Civils de Lyon
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- HEALTH SERVICES RESEARCH
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 2, 2024
First Posted
April 24, 2024
Study Start
October 1, 2024
Primary Completion (Estimated)
April 1, 2028
Study Completion (Estimated)
April 1, 2028
Last Updated
June 11, 2024
Record last verified: 2024-04
Data Sharing
- IPD Sharing
- Will not share