Impact of Body Weight on Outcomes of Patients Undergoing Coronary Artery Bypass Grafting

NCT06614023 | Completed

• 1 other identifier: BNW-1-065/N/3/K
• Study Type: observational
• Target: 6,448
• Locations: 0 countries
• Sites: N/A

Brief Summary

All consecutive patients who underwent isolated coronary artery bypass grafting (CABG) at our institution from 2014 to 2020 were included. Patients were divided into 6 groups according to body mass index (BMI): underweight (BMI \<20.0 kg/m2), normal weight (BMI 20.0-24.9 kg/m2), overweight (BMI, 25-29.9 kg/m2), obesity class I (BMI 30-34.9 kg/m2), obesity class II (BMI 35-39.9 kg/m2) and obesity class III (BMI \>40 kg/m2). The long-term mortality was analyzed as primary end-point. The univariable and multivariable analysis was performed using logistic regression modeling.

Conditions

Obesity; Coronary Artery Disease; Angina Pectoris; Coronary; Ischemic

Keywords

body mass index; coronary artery bypass grafting; obesity; mortality

Outcome Measures

Primary Outcomes (1)

• long-term mortality

  2014-2022

Secondary Outcomes (1)

• sternal wound infection rate

  2014-2022

Study Arms (6)

underweight

BMI \<20.0 kg/m2

Procedure: coronary artery bypass grafting

normal weight

BMI 20.0-24.9 kg/m2

Procedure: coronary artery bypass grafting

overweight

BMI 25-29.9 kg/m2

Procedure: coronary artery bypass grafting

obesity class I

BMI 30-34.9 kg/m2

Procedure: coronary artery bypass grafting

obesity class II

BMI 35-39.9 kg/m2

Procedure: coronary artery bypass grafting

obesity class III

BMI \>40 kg/m2

Procedure: coronary artery bypass grafting

Interventions

coronary artery bypass grafting PROCEDURE

surgical coronary revascularization

normal weight; obesity class I; obesity class II; obesity class III; overweight; underweight

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

all consecutive patients undergoing isolated CABG

You may qualify if:

• patients undergoing isolated CABG

You may not qualify if:

• any concomitant additional surgical procedures

Sponsors & Collaborators

• Medical University of Silesia: lead

MeSH Terms

Conditions

Obesity; Coronary Artery Disease; Angina Pectoris; Ischemia

Interventions

Coronary Artery Bypass

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Coronary Disease; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases; Chest Pain; Pain; Neurologic Manifestations; Pathologic Processes

Intervention Hierarchy (Ancestors)

Myocardial Revascularization; Cardiac Surgical Procedures; Cardiovascular Surgical Procedures; Surgical Procedures, Operative; Vascular Grafting; Vascular Surgical Procedures; Thoracic Surgical Procedures

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 2, 2024
• First Posted: September 26, 2024
• Study Start: January 1, 2014
• Primary Completion: September 30, 2020
• Study Completion: February 1, 2022
• Last Updated: September 26, 2024

Record last verified: 2024-08

Data Sharing

• IPD Sharing: Will not share