NCT06612021

Brief Summary

The aim of study is to evaluate the clinical performance of posterior restorations using HEMA free universal adhesive versus HEMA containing universal adhesive over one year using USPHS criteria.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
64

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jul 2023

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 14, 2023

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

August 25, 2023

Completed
1.1 years until next milestone

First Posted

Study publicly available on registry

September 25, 2024

Completed
19 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 14, 2024

Completed
18 days until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2024

Completed
Last Updated

September 25, 2024

Status Verified

September 1, 2024

Enrollment Period

1.3 years

First QC Date

August 25, 2023

Last Update Submit

September 21, 2024

Conditions

Keywords

HEMA freeHEMA containing adhesiveGiomersGiomerUSPHS criteria

Outcome Measures

Primary Outcomes (1)

  • marginal staining of restoration

    marginal staining using USPHS criteria Alpha: No staining in the margin Bravo: superficial staining on the margin Charlie: deep staining on the margin

    baseline ,6 months & 12 months

Secondary Outcomes (2)

  • caries recurrence

    baseline ,6 months ,12 months

  • marginal adaptation of restoration

    baseline ,6 months and 12 months

Study Arms (2)

HEMA free universal adhesive group

EXPERIMENTAL
Procedure: Beautibond universal adhesive

HEMA containing universal adhesive group

ACTIVE COMPARATOR
Procedure: Tetric N universal bond

Interventions

HEMA free universal adhesive

HEMA free universal adhesive group

HEMA containing universal bond

HEMA containing universal adhesive group

Eligibility Criteria

Age19 Years - 35 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Patients with occlusal caries in molars classified as ICDAS III or IV.
  • years.
  • Males or Females.
  • Co-operative patients approving to participate in the trial.

You may not qualify if:

  • Pregnancy.
  • Disabilities.
  • Systemic disease or severe medical complications.
  • Allergic history concerning methacrylate.
  • Rampant caries.
  • Heavy smoking.
  • Xerostomia.
  • Lack of compliance.
  • Evidence of severe bruxism, clenching, or tempromandibular joint disorders.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of dentistry Cairo university

Cairo, Manyal, 11555, Egypt

Location

MeSH Terms

Conditions

Dental Caries

Condition Hierarchy (Ancestors)

Tooth DemineralizationTooth DiseasesStomatognathic Diseases

Study Officials

  • Alaa F Abdelsalam, phD

    lecturer of conservative dentistry, Cairo university

    PRINCIPAL INVESTIGATOR
  • Hadier M Gad, PhD

    Lecturer of conservative dentistry, Cairo university

    PRINCIPAL INVESTIGATOR
  • Manar A Elmokanen, PhD

    Lecturer of conservative dentistry, Cairo University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
lecturer of conservative dentistry

Study Record Dates

First Submitted

August 25, 2023

First Posted

September 25, 2024

Study Start

July 14, 2023

Primary Completion

October 14, 2024

Study Completion

November 1, 2024

Last Updated

September 25, 2024

Record last verified: 2024-09

Data Sharing

IPD Sharing
Will not share

Locations