Retention Rate And Caries Prevention Of Giomer Based Sealant With And Without Pre-Treatment With Bioactive Glass Air Abrasion In Young Adults

NCT06003452 | Completed

• 1 other identifier: Fissure sealnt
• Study Type: interventional
• Target: 96
• Locations: 1 country
• Sites: 1

Brief Summary

Prevention of oral diseases is preferable to treatment and is the key method of achieving cost effectiveness for oral health improvement programs. Various preventive strategies for dental caries have been tried and are still being developed. The occlusal pits and fissures of posterior teeth are highly susceptible to caries because of the anatomy of pit and fissure surfaces, which favours stagnation of bacteria and substrates. Fissure sealing has been shown to be an evidence-based caries preventive method for protecting the occlusal surfaces against caries. Non- sealed teeth need to be restored approximately 50% more frequently compared to their sealed counterpart. Sealants are effective caries preventive agents as long as they remain bonded to teeth. It has been proposed that sealants should be placed on both sound teeth and incipient non-cavitated carious lesions on permanent teeth of high caries risk patients in order to prevent the onset of caries and its progression. According to the American Dental Association Guidelines for the use of pit and fissure sealants, ICDAS II codes 0, 1 and 2 are recommended for sealant application.A variety of dental materials have been used as sealants using different application techniques. Their effectiveness depends on the formation of a complete seal and is increased by correct technique and moisture control, appropriate follow-up and resealing as necessary. Resin-based conventional sealants are preferred choice, however use of phosphoric acid demineralizes the enamel layer and have elongated treatment time and is more technique sensitive.

Conditions

Dental Caries

Keywords

Fissure sealant; Bio-active glass; caries prevention

Outcome Measures

Primary Outcomes (1)

• Loss of sealant's retention

  Simonsen's criteria Full retention (FR) The material was fully present on the occlusal surfaces Partially lost (PL) The material was present, but as a result of either wear or loss of the material, part of a previously sealed pit or fissure, or both, was exposed \- Totally lost (TL) No trace of the material was detected on the surface.

  6 months

Secondary Outcomes (1)

• Secondary Caries

  6 months

Study Arms (2)

Giomer Based Sealant Without Pre-Treatment With Bioactive Glass Air Abrasion

ACTIVE COMPARATOR

giomer based fissure sealnt will be applied without surface treatment

Procedure: surface treatment with Bioactive Glass Air Abrasion

Giomer Based Sealant With Pre-Treatment With Bioactive Glass Air Abrasion

EXPERIMENTAL

giomer based fissure sealnt will be applied after surface treatment With Bioactive Glass Air Abrasion

Procedure: surface treatment with Bioactive Glass Air Abrasion

Interventions

surface treatment with Bioactive Glass Air Abrasion PROCEDURE

giomer based fissure sealnt will be applied after surface treatment With Bioactive Glass Air Abrasion

Giomer Based Sealant With Pre-Treatment With Bioactive Glass Air Abrasion; Giomer Based Sealant Without Pre-Treatment With Bioactive Glass Air Abrasion

Eligibility Criteria

• Age: 17 Years - 22 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Young adult Patients Aged 17-22.
• Good oral hygiene (plaque index score 0 or 1).
• Absence of abnormal occlusion habits (e.g. bruxism, nail biting, tooth clenching and mouth breathing).
• Patients approving to participate in the study.

You may not qualify if:

• Patients with known allergic or adverse reaction to the tested materials.
• Systematic disease that may affect participation.
• Xerostomic patients.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Dentistry Cairo University

Cairo, Egypt

Location

MeSH Terms

Conditions

Dental Caries

Condition Hierarchy (Ancestors)

Tooth Demineralization; Tooth Diseases; Stomatognathic Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer at faculty of dentistry Cairo university

Study Record Dates

• First Submitted: August 15, 2023
• First Posted: August 22, 2023
• Study Start: January 1, 2024
• Primary Completion: December 1, 2024
• Study Completion: April 1, 2025
• Last Updated: February 3, 2026

Record last verified: 2026-01

Locations

EG (1)