Guaranteed Income and Financial Treatment

NCT06611982 | Active Not Recruiting

• 1 other identifier: UPCC # 31921
• Study Type: interventional
• Target: 250
• Locations: 1 country
• Sites: 3

Brief Summary

The goal of this clinical trial is to learn if providing advanced cancer patients with $1000/month for 12 months will improve cancer outcomes. The main questions it aims to answer are: To what extent does receiving $1000/month additional income reduce financial hardship? To what extent does receiving $1000/month additional income improve quality of life? Does receiving $1000/month additional income improve survival outcomes? Participants will: Receive $1000/month for 12 months Complete a survey every 3 months for 12 months If selected, participate in semi-structured interviews about their financial behaviors

Conditions

Cancer; Financial Hardship; Quality of Life

Outcome Measures

Primary Outcomes (2)

• Financial Toxicity

  COmprehensive Score for Financial Toxicity (COST)

  6 and 12 months from enrollment

• Treatment adherence

  Number of missed appointments in last 30 days

  6 and 12 months from enrollment

Secondary Outcomes (3)

• Health-related quality of life

  6 and 12 months from enrollment

• Anxiety and Depression

  6 and 12 months from enrollment

• Health-related quality of life

  6 and 12 months from enrollment

Other Outcomes (1)

• Mortality

  2, 3, and 5 years from enrollment

Study Arms (2)

Intervention arm

EXPERIMENTAL

Participants assigned to the intervention arm receive $1000/month for 12 months

Other: Unconditional cash transfer

Control arm

OTHER

Participants assigned to the control arm receive information on financial toxicity and the contact information for their social workers and financial counselors

Other: Contact information for social worker and financial counselor

Interventions

Contact information for social worker and financial counselor OTHER

Information on financial toxicity and contact information for social worker and financial counselor

Control arm

Unconditional cash transfer OTHER

$1000/month for 12 months

Intervention arm

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age = 18 or older
• Newly diagnosed or recurrent advanced cancer (Stage 3 or 4)
• Receiving chemotherapy or immunotherapy (with or without radiation) at one of the recruitment sites
• Within 12 months of receiving systemic therapy and on surveillance at one of the recruitment sites
• ECOG performance status of 1 - 2
• A Pennsylvania Medicaid beneficiary
• A Pennsylvania resident

You may not qualify if:

• Eligible for hospice (i.e. determined by provider to have a prognosis of 6 months or less) at time of randomization
• Unable to communicate in English, Spanish, or Mandarin

Sponsors & Collaborators

• Mathematica Policy Research, Inc.: collaborator
• Meredith Doherty, PhD, LCSW: lead

Study Sites (3)

Pennsylvania Hospital

Philadelphia, New York, 19107, United States

Location

Penn Presbyterian Medical Center

Philadelphia, Pennsylvania, 19104, United States

Location

Jefferson Health

Philadelphia, Pennsylvania, 19107, United States

Location

MeSH Terms

Conditions

Neoplasms; Financial Stress

Condition Hierarchy (Ancestors)

Stress, Psychological; Behavioral Symptoms; Behavior

Study Officials

• Meredith Doherty

  University of Pennsylvania

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: April 17, 2024
• First Posted: September 25, 2024
• Study Start: April 1, 2023
• Primary Completion: July 30, 2025
• Study Completion (Estimated): July 30, 2026
• Last Updated: March 25, 2026

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

US (3)