Combined Effects of Isometric Wall Squats and High Intensity Interval Training on Rate Pressure Product in Normotensive and Pre-hypertensive Sedentary Adults

NCT06610006 | Active Not Recruiting

• 1 other identifier: FUI/CTR/2024/34
• Study Type: interventional
• Target: 44
• Locations: 1 country
• Sites: 1

Brief Summary

Hypertension is leading yet preventable risk factor for cardiovascular disease and all-cause mortality worldwide. Prehypertension identifies those at high risk of developing HTN, prompting intervention to prevent or delay the onset of the disease. High intensity interval training (HIIT) is a time efficient mode of training with established benefits, while Isometric wall squats (IWS) also provide a range of proven benefits and advantages, but their combined effect on BP measures is yet to be determined.Hence the objective of this study is to compare the effects of isometric wall squats along with high intensity interval training versus high intensity interval training alone on rate pressure product, SBP and DBP, heart rate and anthropometric measures in normotensive and pre-hypertensive sedentary adults

Conditions

Pre Hypertension

Outcome Measures

Primary Outcomes (7)

• Rate Pressure Product

  Measured by multiplying Heart Rate and Systolic Blood Pressure

  5 weeks

• Blood Pressure(SBP and DBP)

  Evaluation will be done using sphygmomanometer

  5 weeks

• Heart rate

  Heart Rate will be measured using pulse oximeter.

  5 weeks

• Anthropometric Measures Waist circumference

  Measuring Tape will be used to measure Waist circumference

  5 weeks

• Anthropometric Measures hip circumference

  Measuring Tape will be used to measure hip circumference

  5 weeks

• Anthropometric Measures Waist to hip ratio

  Ratio of waist circumference and hip circumference

  5 weeks

• BMI

  Body mass index ratio of weight and height

  5 weeks

Study Arms (2)

High Intensity Interval Training

ACTIVE COMPARATOR

Participants will begin with warm-up exercises for 5-7 mins before the session. Then they will begin high intensity interval training on treadmill with moderate intensity (40-60%HRR) in week 1 to achieve the baseline fitness level and from week 2 to 5 they will progress to high intensity with setting the lower target HR 40-60%HRR and upper target HR 80-85%HRR with 1:4 work to rest ratio followed by 5-7 min of cool-down period.A total of 15 sessions for thrice a week on alternative days for 5 consecutive weeks will be given

Procedure: High Intensity Interval Training (HIIT)

High Intensity Interval Training (HIIT) and Isometric Wall Squat

EXPERIMENTAL

High intensity interval training on treadmill with moderate intensity (40-60%HRR) in week 1 to achieve the baseline fitness level and from week 2 to 5 they will progress to high intensity with setting the lower target HR 40-60%HRR and upper target HR 80-85%HRR with 1:4 work to rest ratio. For isometric wall squat, each training session will be composed of 4 × 2-min bouts of IWS followed by 2-min rest periods At the end of each bout, participants will be given an RPE score. This score will then be compared to a target RPE value and zone for each bout, There will be total 15 sessions thrice a week for 5 weeks.

Procedure: High Intensity Interval Training (HIIT); Procedure: Isometric Wall Squat

Interventions

High Intensity Interval Training (HIIT) PROCEDURE

High intensity interval training on treadmill with moderate intensity (40-60%HRR) in week 1 to achieve the baseline fitness level and from week 2 to 5 they will progress to high intensity with setting the lower target HR 40-60%HRR and upper target HR 80-85%HRR with 1:4 work to rest ratio followed by 5-7 min of cool-down period..A total of 15 sessions of high intensity interval training alone , for thrice a week on alternative days for 5 consecutive weeks will be given. Warm-up session consisting of stretching exercises prior to intervention and cool down session after intervention will also be done and vitals before and after the session will be taken.

High Intensity Interval Training; High Intensity Interval Training (HIIT) and Isometric Wall Squat

Isometric Wall Squat PROCEDURE

For isometric wall squat, each training session will be composed of 4 × 2-min bouts of IWS followed by 2-min rest periods. In first week, participants will do squat training or there will be a protocol for selecting exercise intensity in which participants will be given 30-s to perform a wall squat to select a position that they predict would elicit an target RPE score by varying the squat height. Based on the final squat height and RPE score, after bout 4, participants will be given a starting squat height for training session 1 and will then be progressed in each week

High Intensity Interval Training (HIIT) and Isometric Wall Squat

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Both male and female adults aged 18-45 years.
• Participants lying in Low PA (inactive) category on basis of IPAQ.
• Pre-hypertensive adults:
• SBP- 120 mmHg or more and \<140 mmHg
• DBP of 80 mmHg or more and \< 90 mmHg.

You may not qualify if:

• Diagnosed with any current infections.
• Subjects with any diagnosed cardiovascular or respiratory conditions.
• Subjects with diagnosed musculoskeletal or neurological conditions which hinder participation in physical activity program.
• Active Smokers
• Those with any contraindication to exercise testing or training.
• Pregnant females

Sponsors & Collaborators

• Foundation University Islamabad: lead

Study Sites (1)

Foundation University College of Physical Therapy

Rawalpindi, Punjab Province, 46000, Pakistan

Location

MeSH Terms

Conditions

Prehypertension

Interventions

High-Intensity Interval Training

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: This is a randomized controlled trial having two groups. One group(interventional group) will be doing High Intensity Training (HIIT) and Isometric Wall Squat and the other group (control group) will be doing High intensity Interval Training (HIIT).

Study Record Dates

• First Submitted: September 20, 2024
• First Posted: September 24, 2024
• Study Start: June 10, 2024
• Primary Completion: December 10, 2024
• Study Completion: December 15, 2024
• Last Updated: September 24, 2024

Record last verified: 2024-09

Locations

PA (1)