Acute Effects of Aerobic Exercise on Cognitive Functions in Patients with Chronic Stroke

NCT06596720 | Completed

• 1 other identifier: 60116787-020/46559
• Study Type: interventional
• Target: 32
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this observational study is to investigate the acute effects of aerobic exercise on cognitive functions in patients with chronic stroke. The primary question addressed is: Does aerobic exercise have an impact on cognitive functions in individuals with chronic stroke? Participants with chronic stroke were divided into two groups: those engaging in aerobic exercise and a control group. Both groups underwent cognitive function assessments at intervals of thirty minutes.

Conditions

Aerobic Exercise; Chronic Stroke; Cognitive Function

Keywords

aerobic exercise; chronic stroke; cognitive function

Outcome Measures

Primary Outcomes (3)

• Stroop tests

  This test is a brief measure of selective or focused attention, specifically assessing the ability to shift from one perceptual state to another and suppress response tendencies.

  10 minutes

• Wechsler Forward Digit Span, Wechsler Backward Digit Span

  This test is used to assess attention and short-term memory.

  10 minutes

• CancellationTest

  This test measures sustained attention, visual scanning, reaction time, and response impulsivity.

  5 minutes

Other Outcomes (3)

• Saturation

  5 minutes

• Pulse values

  5 minutes

• Systolic and diastolic blood pressure

  5 minutes

Study Arms (2)

Study group

EXPERIMENTAL

Cognitive assessments for participants in the study group were conducted using the Standardized Mini-Mental State Test, Stroop Test T-BAG Form, Wechsler Digit Span subtest, and Letter Cancellation Test. Participants underwent a thirty-minute session on a moderate-intensity bicycle ergometer. Subsequently, pulse, oxygen saturation, and blood pressure were measured, and the Stroop Test T-BAG Form, Wechsler Digit Span Tests, and Letter Cancellation Tests were repeated.

Other: Aerobic Exercise

Control group

NO INTERVENTION

Cognitive assessments for participants in the control group were conducted using the Standardized Mini-Mental State Test, Stroop Test T-BAG Form, Wechsler Digit Span subtest, and Letter Cancellation Test. The control group was left in a quiet room for thirty minutes. After this period, pulse, oxygen saturation, and blood pressure were measured, and the Stroop Test T-BAG Form, Wechsler Digit Span Tests, and Letter Cancellation Tests were repeated

Interventions

Aerobic Exercise OTHER

After the initial assessments of the individuals in the study group were completed, the exercise program was implemented. The exercise program consisted of 30 minutes of submaximal cycling using the Karvonen formula. The aerobic exercise program was structured with a 5-minute warm-up, a 5-minute cool-down, and the remaining time dedicated to the exercise phase. Since our study included only a single exercise session, a moderate-intensity training program was applied to the participants.

Study group

Eligibility Criteria

• Age: 25 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Having experienced an ischemic or hemorrhagic stroke
• Having been diagnosed with a stroke at least six months prior
• Having not experienced multiple stroke episodes
• Having no communication difficulties
• Being literate

You may not qualify if:

• Having hearing loss
• Receiving additional treatment beyond rehabilitation
• Using a pacemaker
• Presence of cardio-pulmonary disease
• Having experienced a recent trauma
• Having additional neurological disorders aside from stroke
• Having a psychological disorder
• Having a pre-existing condition that affects cognitive level

Sponsors & Collaborators

• Emre BASKAN: lead

Study Sites (1)

Pamukkale University

Denizli, Denizli, Turkey (Türkiye)

Location

MeSH Terms

Interventions

Exercise

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Associate Proffesor

Model Details: For cognitive assessments of the individuals, the Standardized Mini-Mental State Examination, Stroop Test, T-BAG form, Wechsler Digit Span subtest, and Letter Cancellation Test were used. The individuals with stroke in the study group underwent 30 minutes of moderate-intensity cycling on a cycle ergometer. The individuals with stroke in the control group were left in a quiet room for 30 minutes. After this period, both groups had their pulse, saturation, and blood pressure measured again, and the Stroop Test T-BAG Form, Wechsler Digit Span Tests, and Letter Cancellation Tests were repeated.

Study Record Dates

• First Submitted: August 23, 2024
• First Posted: September 19, 2024
• Study Start: September 15, 2020
• Primary Completion: May 2, 2021
• Study Completion: May 27, 2021
• Last Updated: September 19, 2024

Record last verified: 2024-09

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)